WisdomTree BioRevolution Fund (WDNA) belongs to the Health & Biotech Equities category. Below you'll find alternative ETFs from the same category, ranked by key criteria, plus funds that investors commonly compare with WDNA. Use the tables to find lower-cost options, better risk-adjusted returns, or a closer substitute for your current allocation.
Cheapest Alternatives to WDNA
WDNA charges 0.45% annually. There are 22 ETFs in the Health & Biotech Equities category with lower expense ratios, going as low as 0.08%.
| Symbol | Name | Expense Ratio | AUM | Inception | |
|---|---|---|---|---|---|
| Fidelity MSCI Health Care Index ETF | 0.08% | 3.22B | Oct 2013 | WDNA vs FHLC | |
| State Street Health Care Select Sector SPDR ETF | 0.08% | 42.10B | Dec 1998 | WDNA vs XLV | |
| Vanguard Health Care ETF | 0.09% | 20.40B | Jan 2004 | WDNA vs VHT | |
| VanEck Healthcare TruSector ETF | 0.10% | 850.50K | Apr 2026 | WDNA vs TRUH | |
| Portfolio Building Block World Pharma and Biotech ... | 0.13% | 933.15M | Nov 2025 | WDNA vs PBPH |
Best Risk-Adjusted Alternatives to WDNA
WDNA has a PortfoliosLab risk / return rank of 80. There are 22 ETFs in the Health & Biotech Equities category with higher risk-adjusted ranks, going as high as 96.
| Symbol | Name | Risk / Return Rank | AUM | Inception | |
|---|---|---|---|---|---|
| iShares U.S. Pharmaceuticals ETF | 96 | 1.65B | May 2006 | WDNA vs IHE | |
| First Trust Nasdaq Pharmaceuticals ETF | 96 | 911.09M | Sep 2016 | WDNA vs FTXH | |
| Virtus LifeSci Biotech Clinical Trials ETF | 96 | 47.80M | Dec 2014 | WDNA vs BBC | |
| Invesco Dynamic Pharmaceuticals ETF | 95 | 472.10M | Jun 2005 | WDNA vs PJP | |
| ALPS Medical Breakthroughs ETF | 95 | 201.57M | Dec 2014 | WDNA vs SBIO |
Top Performing WDNA Alternatives (YTD)
WDNA is at 15.26% YTD. There are 21 ETFs in the Health & Biotech Equities category with higher YTD returns, going as high as 36.87%.
| Symbol | Name | YTD Return | AUM | Inception | |
|---|---|---|---|---|---|
| AdvisorShares Psychedelics ETF | 36.87% | 48.53M | Sep 2021 | WDNA vs PSIL | |
| ARK Genomic Revolution Multi-Sector ETF | 33.10% | 1.73B | Oct 2014 | WDNA vs ARKG | |
| Roundhill UNH WeeklyPay ETF | 28.78% | 7.27M | Dec 2025 | WDNA vs UNHW | |
| Virtus LifeSci Biotech Clinical Trials ETF | 26.39% | 47.80M | Dec 2014 | WDNA vs BBC | |
| F/m Emerald Life Sciences Innovation ETF | 24.40% | 74.65M | Oct 2024 | WDNA vs LFSC |
Lowest Volatility Alternatives to WDNA
WDNA has 25.54% 1-year volatility. There are 54 ETFs in the Health & Biotech Equities category with lower 1-year volatility, going as low as 0.00%.
| Symbol | Name | Volatility 1Y | AUM | Inception | |
|---|---|---|---|---|---|
| Loncar Cancer Immunotherapy ETF | 0.00% | 12.73M | Oct 2015 | WDNA vs CNCR | |
| Amplify Treatments, Testing and Advancements ETF | 0.00% | 9.68M | Jun 2020 | WDNA vs GERM | |
| Horizon Kinetics SPAC Active ETF | 8.65% | 10.09M | Jun 2007 | WDNA vs SPAQ | |
| Milliman Healthcare Inflation Plus ETF | 10.97% | 982.35K | Apr 2026 | WDNA vs MHIP | |
| State Street Health Care Select Sector SPDR Premiu... | 11.07% | 21.55M | Jul 2025 | WDNA vs XLVI |
Lowest Drawdown Alternatives to WDNA
WDNA has a 1-year max drawdown of -11.70%. There are 26 ETFs in the Health & Biotech Equities category with shallower 1-year drawdowns, going as shallow as 0.00%.
| Symbol | Name | Max Drawdown 1Y | AUM | Inception | |
|---|---|---|---|---|---|
| Amplify Treatments, Testing and Advancements ETF | 0.00% | 9.68M | Jun 2020 | WDNA vs GERM | |
| Horizon Kinetics SPAC Active ETF | -4.20% | 10.09M | Jun 2007 | WDNA vs SPAQ | |
| First Trust Nasdaq Pharmaceuticals ETF | -7.47% | 911.09M | Sep 2016 | WDNA vs FTXH | |
| State Street Health Care Select Sector SPDR Premiu... | -8.14% | 21.55M | Jul 2025 | WDNA vs XLVI | |
| Invesco Nasdaq Biotechnology ETF | -8.34% | 75.06M | Jun 2021 | WDNA vs IBBQ |
Other ETFs from WisdomTree
The 10 most viewed WisdomTree ETFs shown here include USFR, DGRW, GDE and span 15 categories. AUM among these funds goes as high as $18B.
Often Compared With WDNA
Investors most often compare WDNA with AGNG, BBP, HELX. These 20 comparison targets span 3 categories, based on PortfoliosLab usage data.
Compare WDNA with Any Fund or Stock
Compare WDNA with any ETF, mutual fund, or stock using PortfoliosLab's comparison tool.
Pair WDNA with funds that move differently
WisdomTree BioRevolution Fund alternatives help with substitution. Diversifiers are the next step when you want funds with lower historical correlation to WDNA.
Explore WDNA Diversifiers