WDNA vs. GERM

Last updated Jun 5, 2026

WDNA (WisdomTree BioRevolution Fund) and GERM (Amplify Treatments, Testing and Advancements ETF) are both Health & Biotech Equities funds - WDNA tracks the WisdomTree BioRevolution Index while GERM tracks the Prime Treatments, Testing and Advancements Index. Both are passively managed. Over the past year, WDNA returned 50.50% vs 0.00% for GERM. WDNA charges 0.45%/yr vs 0.68%/yr for GERM.

Performance

WDNA vs. GERM - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in WisdomTree BioRevolution Fund (WDNA) and Amplify Treatments, Testing and Advancements ETF (GERM). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

WDNA

• 1D: 2.94%
• 1M: 2.56%
• YTD: 8.96%
• 6M: 10.44%
• 1Y: 50.50%
• 3Y*: 3.54%
• 5Y*: -4.78%
• 10Y*: —

GERM

• 1D: 0.00%
• 1M: 0.00%
• YTD: 0.00%
• 6M: 0.00%
• 1Y: 0.00%
• 3Y*: —
• 5Y*: —
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

WDNA vs. GERM - Yearly Performance Comparison

	2026 (YTD)	2025	2024
WDNA WisdomTree BioRevolution Fund	8.96%	22.68%	-10.00%
GERM Amplify Treatments, Testing and Advancements ETF	0.00%	0.00%	0.00%

WDNA vs. GERM - Sectors Allocation Comparison

Sectors	WDNA	GERM
Healthcare	85.0%	99.3%
Basic Materials	6.5%	-
Consumer Defensive	3.0%	-
Energy	1.1%	-
Communication Services	-	-
Consumer Cyclical	-	-
Financial Services	-	0.4%
Industrials	-	-
Real Estate	-	-
Technology	-	-
Utilities	-	-

Return for Risk

WDNA vs. GERM — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

WDNA

WDNA Risk / Return Rank: 63
WDNA Sharpe Ratio Rank: 59
WDNA Sortino Ratio Rank: 62
WDNA Omega Ratio Rank: 53
WDNA Calmar Ratio Rank: 83
WDNA Martin Ratio Rank: 57

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

WDNA vs. GERM - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for WisdomTree BioRevolution Fund (WDNA) and Amplify Treatments, Testing and Advancements ETF (GERM). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	WDNA	GERM	Difference
Sharpe ratio: Return per unit of total volatility	1.98	—	—
Sortino ratio: Return per unit of downside risk	2.85	—	—
Omega ratio: Gain probability vs. loss probability	1.32	—	—
Calmar ratio: Return relative to maximum drawdown	4.34	—	—
Martin ratio: Return relative to average drawdown	9.85	—	—
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

Sharpe Ratios by Period

	WDNA	GERM	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	1.98	—	—
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	-0.19	—	—
Sharpe Ratio (All Time) Calculated using the full available price history	-0.19	—	—

Drawdowns

WDNA vs. GERM - Drawdown Comparison

The maximum WDNA drawdown since its inception was -58.87%, which is greater than GERM's maximum drawdown of 0.00%. Use the drawdown chart below to compare losses from any high point for WDNA and GERM.

Drawdown Indicators

	WDNA	GERM	Difference
Max Drawdown Largest peak-to-trough decline	-58.87%	0.00%	-58.87%
Max Drawdown (1Y) Largest decline over 1 year	-11.70%	0.00%	-11.70%
Max Drawdown (3Y) Largest decline over 3 years	-38.25%	—	—
Max Drawdown (5Y) Largest decline over 5 years	-58.87%	—	—
Current Drawdown Current decline from peak	-29.86%	0.00%	-29.86%
Average Drawdown Average peak-to-trough decline	-35.64%	0.00%	-35.64%
Ulcer Index Depth and duration of drawdowns from previous peaks	5.14%	0.00%	+5.14%

Volatility

WDNA vs. GERM - Volatility Comparison

WisdomTree BioRevolution Fund (WDNA) has a higher volatility of 7.35% compared to Amplify Treatments, Testing and Advancements ETF (GERM) at 0.00%. This indicates that WDNA's price experiences larger fluctuations and is considered to be riskier than GERM based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	WDNA	GERM	Difference
Volatility (1M) Calculated over the trailing 1-month period	7.35%	0.00%	+7.35%
Volatility (6M) Calculated over the trailing 6-month period	16.59%	0.00%	+16.59%
Volatility (1Y) Calculated over the trailing 1-year period	25.66%	0.00%	+25.66%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	25.08%	0.00%	+25.08%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	25.07%	0.00%	+25.07%

WDNA vs. GERM - Expense Ratio Comparison

WDNA has a 0.45% expense ratio, which is lower than GERM's 0.68% expense ratio.

Dividends

WDNA vs. GERM - Dividend Comparison

WDNA's dividend yield for the trailing twelve months is around 4.19%, while GERM has not paid dividends to shareholders.

Position	TTM	2025	2024	2023	2022	2021
GERM Amplify Treatments, Testing and Advancements ETF	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%
WDNA WisdomTree BioRevolution Fund	4.19%	4.57%	0.75%	0.80%	0.38%	0.10%

Frequently Asked Questions

Which is riskier, WDNA or GERM?

WDNA has higher volatility (7.35%) compared to GERM (0.00%). In terms of maximum drawdown, WDNA dropped -58.87% vs GERM's 0.00%.

Which ETF is better, WDNA or GERM?

On 1-year performance, WDNA leads with 50.50% vs 0.00% for GERM. On fees, WDNA is cheaper at 0.45% per year. On volatility, GERM has been the lower-risk option at 0.00%. The better choice depends on whether you care most about return, fees, risk, or income.

Which ETF has performed better, WDNA or GERM?

Over the 1-year period, WDNA has performed better with a 50.50% return vs 0.00%. Past performance does not guarantee future results, so compare this with risk, fees, and fund exposure.

Which ETF is cheaper, WDNA or GERM?

WDNA is cheaper with a 0.45% expense ratio, compared with 0.68% for GERM.

Which ETF pays a higher dividend yield, WDNA or GERM?

WDNA has the higher dividend yield at 4.19%, compared with 0.00% for GERM.

What is the main difference between WDNA and GERM?

WDNA tracks WisdomTree BioRevolution Index, while GERM tracks Prime Treatments, Testing and Advancements Index. They also come from different issuers: WisdomTree and Amplify. Their fees differ too: 0.45% for WDNA and 0.68% for GERM.