WDNA vs. QGRW

Last updated Aug 2, 2026

WDNA (WisdomTree BioRevolution Fund) and QGRW (WisdomTree U.S. Quality Growth Fund) are both exchange-traded funds - WDNA is a Health & Biotech Equities fund tracking the WisdomTree BioRevolution Index, while QGRW is a Quality Factor fund tracking the WisdomTree U.S. Quality Growth Index. Both are passively managed. Over the past 3 years, WDNA returned 4.46%/yr vs 24.09%/yr for QGRW. Their 0.48 correlation means their historical movements had little consistent relationship. WDNA charges 0.45%/yr vs 0.28%/yr for QGRW.

Performance

WDNA vs. QGRW - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in WisdomTree BioRevolution Fund (WDNA) and WisdomTree U.S. Quality Growth Fund (QGRW). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, WDNA achieves a 15.26% return, which is significantly higher than QGRW's 10.91% return.

WDNA

• 1D: -2.29%
• 1M: -7.98%
• 6M: 8.18%
• YTD: 15.26%
• 1Y: 47.46%
• 3Y*: 4.46%
• 5Y*: -4.37%
• 10Y*: —
• ALL TIME*: -3.49%

QGRW

• 1D: 2.15%
• 1M: -0.09%
• 6M: 10.31%
• YTD: 10.91%
• 1Y: 22.76%
• 3Y*: 24.09%
• 5Y*: —
• 10Y*: —
• ALL TIME*: 31.48%

*Multi-year figures are annualized to reflect compound growth (CAGR)

Liquidity Comparison

Position	Avg. Volume Value (2W)	Avg. Volume Value (1M)	Avg. Volume Value (3M)
QGRW WisdomTree U.S. Quality Growth Fund	$11.15M	$14.16M	$19.72M
WDNA WisdomTree BioRevolution Fund	$25.97K	$30.05K	$24.07K

WDNA vs. QGRW - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022
WDNA WisdomTree BioRevolution Fund	15.26%	22.68%	-14.18%	-2.07%	-4.83%
QGRW WisdomTree U.S. Quality Growth Fund	10.91%	19.20%	34.85%	56.05%	-3.07%

Correlation

The correlation between WDNA and QGRW is 0.41, which is low. Their historical price movements had little consistent relationship.

	Correlation
Correlation (1Y) Focuses on recent behavior, but can change the most.	0.41
Correlation (3Y) Balances recent behavior with more history.	0.46
Correlation (All Time) Calculated using the full available price history since Dec 15, 2022	0.48

WDNA vs. QGRW - Sectors Allocation Comparison

Sectors	WDNA	QGRW
Healthcare	90.0%	5.5%
Basic Materials	6.3%	-
Consumer Defensive	3.7%	0.5%
Energy	1.1%	0.5%
Communication Services	-	15.4%
Consumer Cyclical	-	13.4%
Financial Services	-	3.7%
Industrials	-	9.3%
Real Estate	-	-
Technology	-	50.7%
Utilities	-	0.9%

Return for Risk

WDNA vs. QGRW — Risk / Return Rank

Compare historical risk-adjusted metric ranks over the past 12 months.

WDNA

WDNA Risk / Return Rank: 80
WDNA Sharpe Ratio Rank: 80
WDNA Sortino Ratio Rank: 80
WDNA Omega Ratio Rank: 72
WDNA Calmar Ratio Rank: 91
WDNA Martin Ratio Rank: 74

QGRW

QGRW Risk / Return Rank: 40
QGRW Sharpe Ratio Rank: 42
QGRW Sortino Ratio Rank: 41
QGRW Omega Ratio Rank: 39
QGRW Calmar Ratio Rank: 38
QGRW Martin Ratio Rank: 41

The rank (0–100) uses a weighted average of the Sharpe, Sortino, Omega, Calmar, and Martin percentile ranks for the trailing 12 months. Higher means stronger historical risk-adjusted performance within the peer group.

WDNA vs. QGRW - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for WisdomTree BioRevolution Fund (WDNA) and WisdomTree U.S. Quality Growth Fund (QGRW). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.

	WDNA	QGRW	Difference
Sharpe ratio: Return per unit of total volatility	1.84	1.03	+0.81
Sortino ratio: Return per unit of downside risk	2.61	1.50	+1.11
Omega ratio: Gain probability vs. loss probability	1.30	1.19	+0.12
Calmar ratio: Return relative to maximum drawdown	4.00	1.30	+2.71
Martin ratio: Return relative to average drawdown	9.29	4.44	+4.85

WDNA vs. QGRW - Sharpe Ratio Comparison

The current WDNA Sharpe Ratio is 1.84, which is higher than the QGRW Sharpe Ratio of 1.03. The chart below compares the historical Sharpe Ratios of WDNA and QGRW, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Drawdowns

WDNA vs. QGRW - Drawdown Comparison

The maximum WDNA drawdown since its inception was -58.87%, which is greater than QGRW's maximum drawdown of -24.40%. Use the drawdown chart below to compare losses from any high point for WDNA and QGRW.

Drawdown Indicators

	WDNA	QGRW	Difference
Max Drawdown Largest peak-to-trough decline	-58.87%	-24.40%	-34.47%
Max Drawdown (1Y) Largest decline over 1 year	-11.70%	-15.44%	+3.74%
Max Drawdown (3Y) Largest decline over 3 years	-36.65%	-24.40%	-12.25%
Max Drawdown (5Y) Largest decline over 5 years	-58.87%	—	—
Current Drawdown Current decline from peak	-25.81%	-5.19%	-20.62%
Average Drawdown Average peak-to-trough decline	-35.30%	-3.34%	-31.96%
Ulcer Index Depth and duration of drawdowns from previous peaks	5.03%	4.51%	+0.52%

Volatility

WDNA vs. QGRW - Volatility Comparison

WisdomTree BioRevolution Fund (WDNA) has a higher volatility of 7.04% compared to WisdomTree U.S. Quality Growth Fund (QGRW) at 5.89%. This indicates that WDNA's price experiences larger fluctuations and is considered to be riskier than QGRW based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	WDNA	QGRW	Difference
Volatility (1M) Calculated over the trailing 1-month period	7.04%	5.89%	+1.15%
Volatility (6M) Calculated over the trailing 6-month period	17.23%	15.87%	+1.36%
Volatility (1Y) Calculated over the trailing 1-year period	25.54%	19.49%	+6.05%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	25.26%	21.24%	+4.02%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	25.04%	21.24%	+3.80%

WDNA vs. QGRW - Expense Ratio Comparison

WDNA has a 0.45% expense ratio, which is higher than QGRW's 0.28% expense ratio.

Dividends

WDNA vs. QGRW - Dividend Comparison

WDNA's dividend yield for the trailing twelve months is around 3.96%, more than QGRW's 0.08% yield.

Position	TTM	2025	2024	2023	2022	2021
QGRW WisdomTree U.S. Quality Growth Fund	0.08%	0.09%	0.14%	0.11%	0.00%	0.00%
WDNA WisdomTree BioRevolution Fund	3.96%	4.57%	0.75%	0.80%	0.38%	0.10%

Frequently Asked Questions

Can I hold both WDNA and QGRW in my portfolio?

WDNA and QGRW have a correlation of 0.41, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, WDNA or QGRW?

WDNA has higher volatility (7.04%) compared to QGRW (5.89%). In terms of maximum drawdown, WDNA dropped -58.87% vs QGRW's -24.40%.

Which ETF is better, WDNA or QGRW?

On 3-year performance, QGRW leads with 24.09% vs 4.46% for WDNA. On fees, QGRW is cheaper at 0.28% per year. On volatility, QGRW has been the lower-risk option at 5.89%. The better choice depends on whether you care most about return, fees, risk, or income.

Which ETF has performed better, WDNA or QGRW?

Over the 3-year period, QGRW has performed better with a 24.09% return vs 4.46%. Past performance does not guarantee future results, so compare this with risk, fees, and fund exposure.

Which ETF is cheaper, WDNA or QGRW?

QGRW is cheaper with a 0.28% expense ratio, compared with 0.45% for WDNA.

Which ETF pays a higher dividend yield, WDNA or QGRW?

WDNA has the higher dividend yield at 3.96%, compared with 0.08% for QGRW.

What is the main difference between WDNA and QGRW?

WDNA is categorized as Health & Biotech Equities, while QGRW is Quality Factor. WDNA tracks WisdomTree BioRevolution Index, while QGRW tracks WisdomTree U.S. Quality Growth Index. Their fees differ too: 0.45% for WDNA and 0.28% for QGRW.

Which has better risk-adjusted returns?

WDNA currently has the higher Sharpe Ratio (1.84 vs 1.03), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.