WDNA vs. IHE
Compare and contrast key facts about WisdomTree BioRevolution Fund (WDNA) and iShares U.S. Pharmaceuticals ETF (IHE).
WDNA and IHE are both exchange-traded funds (ETFs), meaning they are traded on stock exchanges and can be bought and sold throughout the day. WDNA is a passively managed fund by WisdomTree that tracks the performance of the WisdomTree BioRevolution Index. It was launched on Jun 3, 2021. IHE is a passively managed fund by iShares that tracks the performance of the Dow Jones U.S. Select Pharmaceuticals Index. It was launched on May 5, 2006. Both WDNA and IHE are passive ETFs, meaning that they are not actively managed but aim to replicate the performance of the underlying index as closely as possible.
Performance
WDNA vs. IHE - Performance Comparison
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WDNA vs. IHE - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | |
|---|---|---|---|---|---|---|
WDNA WisdomTree BioRevolution Fund | 2.99% | 22.68% | -14.18% | -2.07% | -26.29% | -5.27% |
IHE iShares U.S. Pharmaceuticals ETF | 2.52% | 31.69% | 8.13% | 1.06% | -4.87% | 10.42% |
Returns By Period
In the year-to-date period, WDNA achieves a 2.99% return, which is significantly higher than IHE's 2.52% return.
WDNA
- 1D
- 4.08%
- 1M
- -4.89%
- YTD
- 2.99%
- 6M
- 14.31%
- 1Y
- 41.33%
- 3Y*
- 2.41%
- 5Y*
- —
- 10Y*
- —
IHE
- 1D
- 2.95%
- 1M
- -5.31%
- YTD
- 2.52%
- 6M
- 20.67%
- 1Y
- 25.22%
- 3Y*
- 15.99%
- 5Y*
- 9.92%
- 10Y*
- 8.08%
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WDNA vs. IHE - Expense Ratio Comparison
WDNA has a 0.45% expense ratio, which is higher than IHE's 0.42% expense ratio.
Return for Risk
WDNA vs. IHE — Risk / Return Rank
WDNA
IHE
WDNA vs. IHE - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for WisdomTree BioRevolution Fund (WDNA) and iShares U.S. Pharmaceuticals ETF (IHE). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
| WDNA | IHE | Difference | |
|---|---|---|---|
Sharpe ratioReturn per unit of total volatility | 1.40 | 1.23 | +0.18 |
Sortino ratioReturn per unit of downside risk | 2.06 | 1.73 | +0.33 |
Omega ratioGain probability vs. loss probability | 1.25 | 1.23 | +0.02 |
Calmar ratioReturn relative to maximum drawdown | 3.20 | 2.13 | +1.07 |
Martin ratioReturn relative to average drawdown | 7.58 | 6.10 | +1.47 |
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month. | |||
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Sharpe Ratios by Period
| WDNA | IHE | Difference | |
|---|---|---|---|
Sharpe Ratio (1Y)Calculated over the trailing 1-year period | 1.40 | 1.23 | +0.18 |
Sharpe Ratio (5Y)Calculated over the trailing 5-year period | — | 0.63 | — |
Sharpe Ratio (10Y)Calculated over the trailing 10-year period | — | 0.45 | — |
Sharpe Ratio (All Time)Calculated using the full available price history | -0.24 | 0.50 | -0.74 |
Correlation
The correlation between WDNA and IHE is 0.63, which is considered to be moderate. This suggests that the two assets have some degree of positive relationship in their price movements. Moderate correlation can be acceptable for portfolio diversification, offering a balance between risk and potential returns.
Dividends
WDNA vs. IHE - Dividend Comparison
WDNA's dividend yield for the trailing twelve months is around 4.43%, more than IHE's 1.72% yield.
| TTM | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
WDNA WisdomTree BioRevolution Fund | 4.43% | 4.57% | 0.75% | 0.80% | 0.38% | 0.10% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% |
IHE iShares U.S. Pharmaceuticals ETF | 1.72% | 1.76% | 1.73% | 1.39% | 2.01% | 1.49% | 1.19% | 1.40% | 1.25% | 1.36% | 0.92% | 1.93% |
Drawdowns
WDNA vs. IHE - Drawdown Comparison
The maximum WDNA drawdown since its inception was -58.87%, which is greater than IHE's maximum drawdown of -38.20%. Use the drawdown chart below to compare losses from any high point for WDNA and IHE.
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Drawdown Indicators
| WDNA | IHE | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -58.87% | -38.20% | -20.67% |
Max Drawdown (1Y)Largest decline over 1 year | -11.70% | -10.58% | -1.12% |
Max Drawdown (5Y)Largest decline over 5 years | — | -16.03% | — |
Max Drawdown (10Y)Largest decline over 10 years | — | -29.59% | — |
Current DrawdownCurrent decline from peak | -33.71% | -5.31% | -28.40% |
Average DrawdownAverage peak-to-trough decline | -35.79% | -7.95% | -27.84% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 5.20% | 4.73% | +0.47% |
Volatility
WDNA vs. IHE - Volatility Comparison
WisdomTree BioRevolution Fund (WDNA) has a higher volatility of 8.88% compared to iShares U.S. Pharmaceuticals ETF (IHE) at 5.99%. This indicates that WDNA's price experiences larger fluctuations and is considered to be riskier than IHE based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| WDNA | IHE | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 8.88% | 5.99% | +2.89% |
Volatility (6M)Calculated over the trailing 6-month period | 18.59% | 12.34% | +6.25% |
Volatility (1Y)Calculated over the trailing 1-year period | 29.63% | 20.86% | +8.77% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 25.17% | 15.95% | +9.22% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 25.17% | 18.11% | +7.06% |