WDNA vs. AGNG

Last updated Jun 23, 2026

WDNA (WisdomTree BioRevolution Fund) and AGNG (Global X Aging Population ETF) are both Health & Biotech Equities funds - WDNA tracks the WisdomTree BioRevolution Index while AGNG tracks the Indxx Aging Population Thematic Index. Both are passively managed. Over the past 5 years, WDNA returned -4.94%/yr vs 3.32%/yr for AGNG. A 0.70 correlation means they provide meaningful diversification when combined. WDNA charges 0.45%/yr vs 0.50%/yr for AGNG.

Performance

WDNA vs. AGNG - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in WisdomTree BioRevolution Fund (WDNA) and Global X Aging Population ETF (AGNG). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, WDNA achieves a 12.77% return, which is significantly higher than AGNG's -3.52% return.

WDNA

• 1D: 0.90%
• 1M: 8.40%
• YTD: 12.77%
• 6M: 10.12%
• 1Y: 49.11%
• 3Y*: 5.29%
• 5Y*: -4.94%
• 10Y*: —

AGNG

• 1D: 0.48%
• 1M: -3.32%
• YTD: -3.52%
• 6M: -4.27%
• 1Y: 12.25%
• 3Y*: 8.61%
• 5Y*: 3.32%
• 10Y*: 9.27%

*Multi-year figures are annualized to reflect compound growth (CAGR)

WDNA vs. AGNG - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021
WDNA WisdomTree BioRevolution Fund	12.77%	22.68%	-14.18%	-2.07%	-26.29%	-4.92%
AGNG Global X Aging Population ETF	-3.52%	20.01%	7.03%	9.65%	-8.61%	0.16%

Correlation

The correlation between WDNA and AGNG is 0.60, which is moderate. They share some common price drivers but move independently often enough to provide real diversification benefit when combined.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.60
Correlation (3Y) Calculated over the trailing 3-year period	0.63
Correlation (5Y) Calculated over the trailing 5-year period	0.71
Correlation (All Time) Calculated using the full available price history since Jun 3, 2021	0.70

The correlation between WDNA and AGNG shifts across timeframes, from 0.60 (1 year) to 0.70 (5 years), reflecting how their relationship changes across market environments.

WDNA vs. AGNG - Sectors Allocation Comparison

Sectors	WDNA	AGNG
Healthcare	85.0%	91.2%
Basic Materials	6.5%	-
Consumer Defensive	3.0%	-
Energy	1.1%	-
Communication Services	-	-
Consumer Cyclical	-	-
Financial Services	-	-
Industrials	-	-
Real Estate	-	8.9%
Technology	-	-
Utilities	-	-

Return for Risk

WDNA vs. AGNG — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

WDNA

WDNA Risk / Return Rank: 61
WDNA Sharpe Ratio Rank: 58
WDNA Sortino Ratio Rank: 60
WDNA Omega Ratio Rank: 51
WDNA Calmar Ratio Rank: 82
WDNA Martin Ratio Rank: 56

AGNG

AGNG Risk / Return Rank: 24
AGNG Sharpe Ratio Rank: 26
AGNG Sortino Ratio Rank: 26
AGNG Omega Ratio Rank: 24
AGNG Calmar Ratio Rank: 23
AGNG Martin Ratio Rank: 22

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

WDNA vs. AGNG - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for WisdomTree BioRevolution Fund (WDNA) and Global X Aging Population ETF (AGNG). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.

	WDNA	AGNG	Difference
Sharpe ratio: Return per unit of total volatility	1.91	0.90	+1.01
Sortino ratio: Return per unit of downside risk	2.73	1.38	+1.35
Omega ratio: Gain probability vs. loss probability	1.31	1.16	+0.15
Calmar ratio: Return relative to maximum drawdown	4.22	1.07	+3.14
Martin ratio: Return relative to average drawdown	9.45	2.64	+6.81

WDNA vs. AGNG - Sharpe Ratio Comparison

The current WDNA Sharpe Ratio is 1.91, which is higher than the AGNG Sharpe Ratio of 0.90. The chart below compares the historical Sharpe Ratios of WDNA and AGNG, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Drawdowns

WDNA vs. AGNG - Drawdown Comparison

The maximum WDNA drawdown since its inception was -58.87%, which is greater than AGNG's maximum drawdown of -30.58%. Use the drawdown chart below to compare losses from any high point for WDNA and AGNG.

Drawdown Indicators

	WDNA	AGNG	Difference
Max Drawdown Largest peak-to-trough decline	-58.87%	-30.58%	-28.29%
Max Drawdown (1Y) Largest decline over 1 year	-11.70%	-11.45%	-0.25%
Max Drawdown (3Y) Largest decline over 3 years	-38.25%	-14.48%	-23.77%
Max Drawdown (5Y) Largest decline over 5 years	-58.87%	-25.66%	-33.21%
Max Drawdown (10Y) Largest decline over 10 years	—	-30.58%	—
Current Drawdown Current decline from peak	-27.41%	-9.90%	-17.51%
Average Drawdown Average peak-to-trough decline	-35.57%	-5.97%	-29.60%
Ulcer Index Depth and duration of drawdowns from previous peaks	5.21%	4.65%	+0.56%

Volatility

WDNA vs. AGNG - Volatility Comparison

WisdomTree BioRevolution Fund (WDNA) has a higher volatility of 7.42% compared to Global X Aging Population ETF (AGNG) at 4.28%. This indicates that WDNA's price experiences larger fluctuations and is considered to be riskier than AGNG based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	WDNA	AGNG	Difference
Volatility (1M) Calculated over the trailing 1-month period	7.42%	4.28%	+3.14%
Volatility (6M) Calculated over the trailing 6-month period	16.98%	10.27%	+6.71%
Volatility (1Y) Calculated over the trailing 1-year period	25.95%	13.70%	+12.25%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	25.14%	15.22%	+9.92%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	25.07%	17.14%	+7.93%

WDNA vs. AGNG - Expense Ratio Comparison

WDNA has a 0.45% expense ratio, which is lower than AGNG's 0.50% expense ratio.

Dividends

WDNA vs. AGNG - Dividend Comparison

WDNA's dividend yield for the trailing twelve months is around 4.05%, more than AGNG's 0.91% yield.

Position	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016
AGNG Global X Aging Population ETF	0.91%	0.88%	0.83%	0.96%	0.49%	0.72%	0.36%	0.83%	1.00%	1.04%	0.45%
WDNA WisdomTree BioRevolution Fund	4.05%	4.57%	0.75%	0.80%	0.38%	0.10%	0.00%	0.00%	0.00%	0.00%	0.00%

Frequently Asked Questions

Can I hold both WDNA and AGNG in my portfolio?

WDNA and AGNG have a correlation of 0.60, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, WDNA or AGNG?

WDNA has higher volatility (7.42%) compared to AGNG (4.28%). In terms of maximum drawdown, WDNA dropped -58.87% vs AGNG's -30.58%.

Which ETF is better, WDNA or AGNG?

On 5-year performance, AGNG leads with 3.32% vs -4.94% for WDNA. On fees, WDNA is cheaper at 0.45% per year. On volatility, AGNG has been the lower-risk option at 4.28%. The better choice depends on whether you care most about return, fees, risk, or income.

Which ETF has performed better, WDNA or AGNG?

Over the 5-year period, AGNG has performed better with a 3.32% return vs -4.94%. Past performance does not guarantee future results, so compare this with risk, fees, and fund exposure.

Which ETF is cheaper, WDNA or AGNG?

WDNA is cheaper with a 0.45% expense ratio, compared with 0.50% for AGNG.

Which ETF pays a higher dividend yield, WDNA or AGNG?

WDNA has the higher dividend yield at 4.05%, compared with 0.91% for AGNG.

What is the main difference between WDNA and AGNG?

WDNA tracks WisdomTree BioRevolution Index, while AGNG tracks Indxx Aging Population Thematic Index. They also come from different issuers: WisdomTree and Global X. Their fees differ too: 0.45% for WDNA and 0.50% for AGNG.

Which has better risk-adjusted returns?

WDNA currently has the higher Sharpe Ratio (1.91 vs 0.90), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.