WDNA vs. FBIOX

Last updated Jun 24, 2026

WDNA (WisdomTree BioRevolution Fund) and FBIOX (Fidelity Select Biotechnology Portfolio) are both Health & Biotech Equities funds. Over the past 5 years, WDNA returned -5.03%/yr vs 6.76%/yr for FBIOX. Their correlation of 0.87 suggests significant overlap in exposure. WDNA charges 0.45%/yr vs 0.69%/yr for FBIOX.

Performance

WDNA vs. FBIOX - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in WisdomTree BioRevolution Fund (WDNA) and Fidelity Select Biotechnology Portfolio (FBIOX). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, WDNA achieves a 13.32% return, which is significantly higher than FBIOX's 11.03% return.

WDNA

• 1D: 0.49%
• 1M: 8.93%
• YTD: 13.32%
• 6M: 11.11%
• 1Y: 50.90%
• 3Y*: 5.47%
• 5Y*: -5.03%
• 10Y*: —

FBIOX

• 1D: 2.80%
• 1M: 6.82%
• YTD: 11.03%
• 6M: 8.61%
• 1Y: 58.91%
• 3Y*: 20.04%
• 5Y*: 6.76%
• 10Y*: 11.69%

*Multi-year figures are annualized to reflect compound growth (CAGR)

WDNA vs. FBIOX - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021
WDNA WisdomTree BioRevolution Fund	13.32%	22.68%	-14.18%	-2.07%	-26.29%	-4.92%
FBIOX Fidelity Select Biotechnology Portfolio	11.03%	36.38%	7.26%	10.09%	-15.87%	-2.57%

Correlation

The correlation between WDNA and FBIOX is 0.80, indicating a strong positive relationship between their price movements. Combining them offers limited diversification - they tend to fall together during downturns.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.80
Correlation (3Y) Calculated over the trailing 3-year period	0.83
Correlation (5Y) Calculated over the trailing 5-year period	0.87
Correlation (All Time) Calculated using the full available price history since Jun 3, 2021	0.87

The correlation between WDNA and FBIOX has been stable across timeframes, ranging from 0.80 to 0.87 - a consistent structural relationship.

WDNA vs. FBIOX - Sectors Allocation Comparison

Sectors	WDNA	FBIOX
Healthcare	85.0%	100.0%
Basic Materials	6.5%	-
Consumer Defensive	3.0%	-
Energy	1.1%	-
Communication Services	-	-
Consumer Cyclical	-	-
Financial Services	-	-
Industrials	-	-
Real Estate	-	-
Technology	-	-
Utilities	-	-

Return for Risk

WDNA vs. FBIOX — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

WDNA

WDNA Risk / Return Rank: 66
WDNA Sharpe Ratio Rank: 65
WDNA Sortino Ratio Rank: 66
WDNA Omega Ratio Rank: 56
WDNA Calmar Ratio Rank: 85
WDNA Martin Ratio Rank: 59

FBIOX

FBIOX Risk / Return Rank: 88
FBIOX Sharpe Ratio Rank: 90
FBIOX Sortino Ratio Rank: 84
FBIOX Omega Ratio Rank: 73
FBIOX Calmar Ratio Rank: 98
FBIOX Martin Ratio Rank: 97

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

WDNA vs. FBIOX - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for WisdomTree BioRevolution Fund (WDNA) and Fidelity Select Biotechnology Portfolio (FBIOX). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.

	WDNA	FBIOX	Difference
Sharpe ratio: Return per unit of total volatility	1.98	2.74	-0.76
Sortino ratio: Return per unit of downside risk	2.81	3.65	-0.84
Omega ratio: Gain probability vs. loss probability	1.32	1.44	-0.12
Calmar ratio: Return relative to maximum drawdown	4.37	7.66	-3.29
Martin ratio: Return relative to average drawdown	9.80	23.32	-13.52

WDNA vs. FBIOX - Sharpe Ratio Comparison

The current WDNA Sharpe Ratio is 1.98, which is comparable to the FBIOX Sharpe Ratio of 2.74. The chart below compares the historical Sharpe Ratios of WDNA and FBIOX, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Drawdowns

WDNA vs. FBIOX - Drawdown Comparison

The maximum WDNA drawdown since its inception was -58.87%, smaller than the maximum FBIOX drawdown of -71.98%. Use the drawdown chart below to compare losses from any high point for WDNA and FBIOX.

Drawdown Indicators

	WDNA	FBIOX	Difference
Max Drawdown Largest peak-to-trough decline	-58.87%	-71.98%	+13.11%
Max Drawdown (1Y) Largest decline over 1 year	-11.70%	-7.62%	-4.08%
Max Drawdown (3Y) Largest decline over 3 years	-38.25%	-27.83%	-10.42%
Max Drawdown (5Y) Largest decline over 5 years	-58.87%	-44.87%	-14.00%
Max Drawdown (10Y) Largest decline over 10 years	—	-48.66%	—
Current Drawdown Current decline from peak	-27.05%	0.00%	-27.05%
Average Drawdown Average peak-to-trough decline	-35.56%	-23.60%	-11.96%
Ulcer Index Depth and duration of drawdowns from previous peaks	5.21%	2.50%	+2.71%

Volatility

WDNA vs. FBIOX - Volatility Comparison

The current volatility for WisdomTree BioRevolution Fund (WDNA) is 7.39%, while Fidelity Select Biotechnology Portfolio (FBIOX) has a volatility of 8.04%. This indicates that WDNA experiences smaller price fluctuations and is considered to be less risky than FBIOX based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	WDNA	FBIOX	Difference
Volatility (1M) Calculated over the trailing 1-month period	7.39%	8.04%	-0.65%
Volatility (6M) Calculated over the trailing 6-month period	16.98%	17.08%	-0.10%
Volatility (1Y) Calculated over the trailing 1-year period	25.90%	21.36%	+4.54%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	25.14%	25.03%	+0.11%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	25.06%	26.26%	-1.20%

WDNA vs. FBIOX - Expense Ratio Comparison

WDNA has a 0.45% expense ratio, which is lower than FBIOX's 0.69% expense ratio.

Dividends

WDNA vs. FBIOX - Dividend Comparison

WDNA's dividend yield for the trailing twelve months is around 4.03%, less than FBIOX's 6.06% yield.

Position	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
FBIOX Fidelity Select Biotechnology Portfolio	6.06%	2.47%	1.21%	0.45%	0.00%	14.48%	19.46%	8.89%	11.18%	1.41%	3.42%	6.71%
WDNA WisdomTree BioRevolution Fund	4.03%	4.57%	0.75%	0.80%	0.38%	0.10%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%

Frequently Asked Questions

Can I hold both WDNA and FBIOX in my portfolio?

WDNA and FBIOX have a correlation of 0.80, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, WDNA or FBIOX?

FBIOX has higher volatility (8.04%) compared to WDNA (7.39%). In terms of maximum drawdown, WDNA dropped -58.87% vs FBIOX's -71.98%.

Which has better risk-adjusted returns?

FBIOX currently has the higher Sharpe Ratio (2.74 vs 1.98), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.