- ISIN
- US46436E3532
- Issuer
- iShares
- Inception Date
- Aug 24, 2022
- Region
- Global (Broad)
- Category
- Health & Biotech Equities
- Leveraged
- 1x (No leverage)
- Index Tracked
- NYSE FactSet Global Neuro Biopharma and MedTech Index
- Distribution Policy
- Distributing
- Asset Class
- Equity
- Asset Class Size
- Small-Cap
- Asset Class Style
- Growth
- Assets Under Management
- $5M
Share Price Chart
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Performance
IBRN Performance Chart
iShares Neuroscience and Healthcare ETF (IBRN) is up 13.5% since the beginning of the year. IBRN is currently trading at $37 per share.
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Returns By Period
iShares Neuroscience and Healthcare ETF (IBRN) has returned 13.46% so far this year and 68.35% over the past 12 months.
iShares Neuroscience and Healthcare ETF
- 1D
- 1.81%
- 1M
- 5.85%
- YTD
- 13.46%
- 6M
- 12.79%
- 1Y
- 68.35%
- 3Y*
- 14.49%
- 5Y*
- —
- 10Y*
- —
Benchmark (S&P 500 Index)
- 1D
- -0.37%
- 1M
- -0.01%
- YTD
- 9.16%
- 6M
- 8.64%
- 1Y
- 25.22%
- 3Y*
- 19.78%
- 5Y*
- 11.99%
- 10Y*
- 13.88%
IBRN Monthly Returns History
Based on dividend-adjusted daily data since Aug 26, 2022, IBRN's average daily return is +0.05%, while the average monthly return is +1.00%. At this rate, an investment would double in approximately 5.8 years.
Historically, 62% of months were positive and 38% were negative. The best month was Dec 2023 with a return of +22.2%, while the worst month was Mar 2025 at -9.9%. The longest winning streak lasted 7 consecutive months, and the longest losing streak was 3 months.
On a daily basis, IBRN closed higher 52% of trading days. The best single day was Sep 28, 2022 with a return of +7.6%, while the worst single day was May 6, 2025 at -6.4%.
| Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec | Total | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2026 | 0.85% | -1.58% | 2.75% | 4.66% | 3.93% | 2.29% | 13.46% | ||||||
| 2025 | 2.27% | -4.50% | -9.93% | 1.60% | -3.25% | -0.27% | 6.52% | 7.14% | 7.17% | 12.82% | 5.02% | 2.82% | 28.49% |
| 2024 | -2.74% | 0.93% | -0.70% | -8.00% | 0.22% | 0.01% | 8.90% | 0.71% | -3.23% | 6.90% | 1.36% | -5.95% | -2.78% |
| 2023 | 3.56% | -6.66% | -5.09% | 3.77% | -2.15% | 0.35% | 1.52% | -6.55% | -8.93% | -7.78% | 10.87% | 22.21% | 0.92% |
| 2022 | -4.28% | 2.51% | 1.92% | 5.45% | -2.45% | 2.87% |
Benchmark Metrics
iShares Neuroscience and Healthcare ETF has an annualized alpha of -2.82%, beta of 0.99, and R2 of 0.39 versus S&P 500 Index. Calculated based on daily prices since August 26, 2022.
- This ETF participated in 90.69% of S&P 500 Index downside but only 73.73% of its upside - more exposed to losses than it benefited from rallies.
- R2 of 0.39 means the benchmark explains less than half of this ETF's behavior - treat beta with caution or consider switching to a more representative benchmark.
- Alpha
- -2.82%
- Beta
- 0.99
- R²
- 0.39
- Upside Capture
- 73.73%
- Downside Capture
- 90.69%
Expense Ratio
IBRN has an expense ratio of 0.47%, placing it in the medium range.
Return for Risk
Risk / Return Rank
IBRN ranks 87 for risk / return — in the top 87% of ETFs on our site. This means strong returns relative to risk — exactly what professional investors look for. Well-suited for investors who want to maximize return per unit of risk.
Return / Risk — by metrics
The table below present risk-adjusted performance metrics for iShares Neuroscience and Healthcare ETF (IBRN) and compare them to S&P 500 Index.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| IBRN | Benchmark | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | +0.66 | ||
| Sortino ratioReturn per unit of downside risk | +0.84 | ||
| Omega ratioGain probability vs. loss probability | 1.42 | 1.37 | +0.05 |
| Calmar ratioReturn relative to maximum drawdown | 7.80 | 2.78 | +5.02 |
| Martin ratioReturn relative to average drawdown | 22.04 | 12.44 | +9.60 |
Dividends
Dividend History
iShares Neuroscience and Healthcare ETF provided a 0.87% dividend yield over the last twelve months, with an annual payout of $0.32 per share. The fund has been increasing its distributions for 2 consecutive years.
| Period | TTM | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Dividend | $0.32 | $0.32 | $0.10 | $0.01 |
Dividend yield | 0.87% | 0.99% | 0.40% | 0.06% |
Monthly Dividends
The table displays the monthly dividend distributions for iShares Neuroscience and Healthcare ETF. The dividends shown in the table have been adjusted to account for any splits that may have occurred.
| Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec | Total | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2026 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | ||||||
| 2025 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.32 | $0.32 |
| 2024 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.10 | $0.10 |
| 2023 | $0.01 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.01 | $0.01 |
Drawdowns
Drawdowns Chart
The Drawdowns chart displays portfolio losses from any high point along the way. Drawdowns are calculated considering price movements and all distributions paid, if any.
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Worst Drawdowns
The table below displays the maximum drawdowns of the iShares Neuroscience and Healthcare ETF. A maximum drawdown is a measure of risk, indicating the largest reduction in portfolio value due to a series of losing trades.
The maximum drawdown for the iShares Neuroscience and Healthcare ETF was 35.38%, occurring on Apr 8, 2025. Recovery took 132 trading sessions.
Related event | Drawdown | Fall | Recovery | Underwater |
|---|---|---|---|---|
2025 selloff2025 | -35.38%Apr 2025 | 4mo 27d | 6mo 11d | 11mo 8dNov 2024 - Oct 2025 |
2023 bear market2023 | -30.32%Oct 2023 | 8mo 26d | 11mo 26d | 1y 8moFeb 2023 - Oct 2024 |
Bear market2022 | -9.30%Sep 2022 | 10d | 11d | 21dSep 2022 - Oct 2022 |
2026 pullback2026 | -8.80%Mar 2026 | 1mo 26d | 19d | 2mo 15dJan 2026 - Apr 2026 |
2025 pullback2025 | -8.01%Nov 2025 | 9d | 17d | 26dOct 2025 - Nov 2025 |
Drawdown Indicators
| IBRN | Benchmark | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -35.38% | -56.78% | +21.40% |
Max Drawdown (1Y)Largest decline over 1 year | -8.80% | -9.10% | +0.30% |
Max Drawdown (3Y)Largest decline over 3 years | -35.38% | -18.90% | -16.48% |
Max Drawdown (5Y)Largest decline over 5 years | — | -25.43% | — |
Max Drawdown (10Y)Largest decline over 10 years | — | -33.92% | — |
Current DrawdownCurrent decline from peak | 0.00% | -1.80% | +1.80% |
Average DrawdownAverage peak-to-trough decline | -9.76% | -10.71% | +0.95% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 3.11% | 2.03% | +1.08% |
Volatility
Volatility Chart
The chart below shows the rolling one-month volatility.
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