Amplify Treatments, Testing and Advancements ETF (GERM) belongs to the Health & Biotech Equities category. Below you'll find alternative ETFs from the same category, ranked by key criteria, plus funds that investors commonly compare with GERM. Use the tables to find lower-cost options, better risk-adjusted returns, or a closer substitute for your current allocation.
Cheapest Alternatives to GERM
GERM charges 0.68% annually. There are 42 ETFs in the Health & Biotech Equities category with lower expense ratios, going as low as 0.08%.
| Symbol | Name | Expense Ratio | AUM | Inception | |
|---|---|---|---|---|---|
| Fidelity MSCI Health Care Index ETF | 0.08% | 2.85B | Oct 2013 | GERM vs FHLC | |
| State Street Health Care Select Sector SPDR ETF | 0.08% | 38.66B | Dec 1998 | GERM vs XLV | |
| Vanguard Health Care ETF | 0.09% | 18.50B | Jan 2004 | GERM vs VHT | |
| Portfolio Building Block World Pharma and Biotech ... | 0.13% | 9.98M | Nov 2025 | GERM vs PBPH | |
| Invesco S&P SmallCap Health Care ETF | 0.29% | 131.36M | Apr 2010 | GERM vs PSCH |
Best Risk-Adjusted Alternatives to GERM
Among 54 ETFs in the Health & Biotech Equities category with risk / return rank data, the top risk-adjusted alternatives shown here go as high as 89.
| Symbol | Name | Risk / Return Rank | AUM | Inception | |
|---|---|---|---|---|---|
| Virtus LifeSci Biotech Clinical Trials ETF | 89 | 43.63M | Dec 2014 | GERM vs BBC | |
| SPDR S&P Biotech ETF | 74 | 8.28B | Feb 2006 | GERM vs XBI | |
| iShares U.S. Pharmaceuticals ETF | 74 | 912.87M | May 2006 | GERM vs IHE | |
| ALPS Medical Breakthroughs ETF | 72 | 161.79M | Dec 2014 | GERM vs SBIO | |
| First Trust Nasdaq Pharmaceuticals ETF | 71 | 35.04M | Sep 2016 | GERM vs FTXH |
Top Performing GERM Alternatives (YTD)
GERM is at 0.00% YTD. There are 28 ETFs in the Health & Biotech Equities category with higher YTD returns, going as high as 20.15%.
| Symbol | Name | YTD Return | AUM | Inception | |
|---|---|---|---|---|---|
| AdvisorShares Psychedelics ETF | 20.15% | 35.56M | Sep 2021 | GERM vs PSIL | |
| ARK Genomic Revolution Multi-Sector ETF | 17.09% | 1.24B | Oct 2014 | GERM vs ARKG | |
| Roundhill UNH WeeklyPay ETF | 15.08% | 4.48M | Dec 2025 | GERM vs UNHW | |
| iShares Genomics Immunology and Healthcare ETF Gen... | 10.31% | 163.14M | Jun 2019 | GERM vs IDNA | |
| Virtus LifeSci Biotech Clinical Trials ETF | 8.64% | 43.63M | Dec 2014 | GERM vs BBC |
Lowest Volatility Alternatives to GERM
GERM has 0.00% 1-year volatility. No ETFs in the Health & Biotech Equities category have lower 1-year volatility; the lowest-volatility alternatives shown here go as low as 0.00%.
| Symbol | Name | Volatility 1Y | AUM | Inception | |
|---|---|---|---|---|---|
| Principal Healthcare Innovators Index ETF | 0.00% | 16.16M | Aug 2016 | GERM vs BTEC | |
| Loncar Cancer Immunotherapy ETF | 0.00% | 12.73M | Oct 2015 | GERM vs CNCR | |
| Horizon Kinetics SPAC Active ETF | 8.80% | 10.01M | Jun 2007 | GERM vs SPAQ | |
| State Street Health Care Select Sector SPDR Premiu... | 10.94% | 14.25M | Jul 2025 | GERM vs XLVI | |
| Global X Aging Population ETF | 13.62% | 81.82M | May 2016 | GERM vs AGNG |
Lowest Drawdown Alternatives to GERM
GERM has a 1-year max drawdown of 0.00%. No ETFs in the Health & Biotech Equities category have shallower 1-year drawdowns; the lowest-drawdown alternatives shown here go as shallow as -5.30%.
| Symbol | Name | Max Drawdown 1Y | AUM | Inception | |
|---|---|---|---|---|---|
| Horizon Kinetics SPAC Active ETF | -5.30% | 10.01M | Jun 2007 | GERM vs SPAQ | |
| First Trust Nasdaq Pharmaceuticals ETF | -7.47% | 35.04M | Sep 2016 | GERM vs FTXH | |
| Invesco Nasdaq Biotechnology ETF | -8.34% | 67.37M | Jun 2021 | GERM vs IBBQ | |
| iShares U.S. Pharmaceuticals ETF | -8.47% | 912.87M | May 2006 | GERM vs IHE | |
| Tema Oncology ETF | -8.67% | 142.24M | Aug 2023 | GERM vs CANC |
Other ETFs from Amplify
The 10 most viewed Amplify ETFs shown here include DIVO, QDVO, IDVO and span 10 categories. AUM among these funds goes as high as $7B.
Often Compared With GERM
Investors most often compare GERM with EQRR, GDOC, MDEV. These 20 comparison targets span 7 categories, based on PortfoliosLab usage data.
Compare GERM with Any Fund or Stock
Compare GERM with any ETF, mutual fund, or stock using PortfoliosLab's comparison tool.
Pair GERM with funds that move differently
Amplify Treatments, Testing and Advancements ETF alternatives help with substitution. Diversifiers are the next step when you want funds with lower historical correlation to GERM.
Explore GERM Diversifiers