Amplify Treatments, Testing and Advancements ETF (GERM) belongs to the Health & Biotech Equities category. Below you'll find alternative ETFs from the same category, ranked by key criteria, plus funds that investors commonly compare with GERM. Use the tables to find lower-cost options, better risk-adjusted returns, or a closer substitute for your current allocation.
Cheapest Alternatives to GERM
GERM charges 0.68% annually. There are 44 ETFs in the Health & Biotech Equities category with lower expense ratios, going as low as 0.08%.
| Symbol | Name | Expense Ratio | AUM | Inception | |
|---|---|---|---|---|---|
| Fidelity MSCI Health Care Index ETF | 0.08% | 3.22B | Oct 2013 | GERM vs FHLC | |
| State Street Health Care Select Sector SPDR ETF | 0.08% | 41.65B | Dec 1998 | GERM vs XLV | |
| Vanguard Health Care ETF | 0.09% | 19.00B | Jan 2004 | GERM vs VHT | |
| Portfolio Building Block World Pharma and Biotech ... | 0.13% | 951.16M | Nov 2025 | GERM vs PBPH | |
| GSK plc ADRhedged ETF | 0.19% | 793.18K | Jan 2025 | GERM vs GSKH |
Best Risk-Adjusted Alternatives to GERM
Among 56 ETFs in the Health & Biotech Equities category with risk / return rank data, the top risk-adjusted alternatives shown here go as high as 96.
| Symbol | Name | Risk / Return Rank | AUM | Inception | |
|---|---|---|---|---|---|
| Virtus LifeSci Biotech Clinical Trials ETF | 96 | 57.56M | Dec 2014 | GERM vs BBC | |
| ALPS Medical Breakthroughs ETF | 94 | 213.08M | Dec 2014 | GERM vs SBIO | |
| First Trust Nasdaq Pharmaceuticals ETF | 94 | 36.36M | Sep 2016 | GERM vs FTXH | |
| iShares U.S. Pharmaceuticals ETF | 93 | 1.34B | May 2006 | GERM vs IHE | |
| SPDR S&P Biotech ETF | 93 | 11.10B | Feb 2006 | GERM vs XBI |
Top Performing GERM Alternatives (YTD)
GERM is at 0.00% YTD. There are 57 ETFs in the Health & Biotech Equities category with higher YTD returns, going as high as 41.35%.
| Symbol | Name | YTD Return | AUM | Inception | |
|---|---|---|---|---|---|
| AdvisorShares Psychedelics ETF | 41.35% | 44.37M | Sep 2021 | GERM vs PSIL | |
| ARK Genomic Revolution Multi-Sector ETF | 38.38% | 1.31B | Oct 2014 | GERM vs ARKG | |
| Roundhill UNH WeeklyPay ETF | 31.46% | 6.01M | Dec 2025 | GERM vs UNHW | |
| Virtus LifeSci Biotech Clinical Trials ETF | 29.44% | 57.56M | Dec 2014 | GERM vs BBC | |
| SPDR S&P Health Care Services ETF | 26.76% | 204.10M | Sep 2011 | GERM vs XHS |
Lowest Volatility Alternatives to GERM
GERM has 0.00% 1-year volatility. No ETFs in the Health & Biotech Equities category have lower 1-year volatility; the lowest-volatility alternatives shown here go as low as 0.00%.
| Symbol | Name | Volatility 1Y | AUM | Inception | |
|---|---|---|---|---|---|
| Loncar Cancer Immunotherapy ETF | 0.00% | 12.73M | Oct 2015 | GERM vs CNCR | |
| Horizon Kinetics SPAC Active ETF | 8.62% | 10.11M | Jun 2007 | GERM vs SPAQ | |
| State Street Health Care Select Sector SPDR Premiu... | 11.06% | 16.78M | Jul 2025 | GERM vs XLVI | |
| Milliman Healthcare Inflation Plus ETF | 11.54% | 982.35K | Apr 2026 | GERM vs MHIP | |
| Global X Aging Population ETF | 14.11% | 85.65M | May 2016 | GERM vs AGNG |
Lowest Drawdown Alternatives to GERM
GERM has a 1-year max drawdown of 0.00%. No ETFs in the Health & Biotech Equities category have shallower 1-year drawdowns; the lowest-drawdown alternatives shown here go as shallow as -4.32%.
| Symbol | Name | Max Drawdown 1Y | AUM | Inception | |
|---|---|---|---|---|---|
| Horizon Kinetics SPAC Active ETF | -4.32% | 10.11M | Jun 2007 | GERM vs SPAQ | |
| First Trust Nasdaq Pharmaceuticals ETF | -7.47% | 36.36M | Sep 2016 | GERM vs FTXH | |
| Invesco Nasdaq Biotechnology ETF | -8.34% | 74.65M | Jun 2021 | GERM vs IBBQ | |
| iShares U.S. Pharmaceuticals ETF | -8.47% | 1.34B | May 2006 | GERM vs IHE | |
| iShares Neuroscience and Healthcare ETF | -8.80% | 5.85M | Aug 2022 | GERM vs IBRN |
Other ETFs from Amplify
The 10 most viewed Amplify ETFs shown here include DIVO, QDVO, IDVO and span 12 categories. AUM among these funds goes as high as $7B.
| Symbol | Name | Category | Risk / Return Rank | YTD Return | AUM | Inception | |
|---|---|---|---|---|---|---|---|
| Amplify CWP Enhanced Dividend Income ETF | Derivative Income | 72 | 7.50% | 7.30B | Dec 2016 | GERM vs DIVO | |
| Amplify CWP Growth & Income ETF | Derivative Income | 49 | 8.27% | 728.58M | Aug 2024 | GERM vs QDVO | |
| Amplify CWP International Enhanced Dividend Income... | Derivative Income, Dividend, Foreign Large Cap Equities | 75 | 13.48% | 1.30B | Sep 2022 | GERM vs IDVO | |
| Amplify Junior Silver Miners ETF | Silver, Precious Metals | 33 | -13.91% | 3.22B | Nov 2012 | GERM vs SILJ | |
| Amplify Blockchain Technology ETF | Blockchain, Technology Equities | 10 | 4.97% | 1.14B | Jan 2018 | GERM vs BLOK | |
| Amplify AI Powered Equity ETF | Large Cap Growth Equities | 52 | 11.43% | 121.92M | Oct 2017 | GERM vs AIEQ | |
| Amplify Cybersecurity ETF | Technology Equities, Cybersecurity | 36 | 36.99% | 2.70B | Nov 2014 | GERM vs HACK | |
| Breakwave Tanker Shipping ETF | Commodities | 99 | 1,090.11% | 22.86M | May 2023 | GERM vs BWET | |
| Amplify CEF High Income ETF | Diversified Portfolio | 43 | 6.40% | 722.43M | Jun 2012 | GERM vs YYY | |
| Amplify Lithium & Battery Technology ETF | Lithium & Battery Metals | 49 | 2.90% | 118.16M | Jun 2018 | GERM vs BATT |
Often Compared With GERM
Investors most often compare GERM with GDOC, EQRR, MDEV. These 20 comparison targets span 5 categories, based on PortfoliosLab usage data.
Compare GERM with Any Fund or Stock
Compare GERM with any ETF, mutual fund, or stock using PortfoliosLab's comparison tool.
Pair GERM with funds that move differently
Amplify Treatments, Testing and Advancements ETF alternatives help with substitution. Diversifiers are the next step when you want funds with lower historical correlation to GERM.
Explore GERM Diversifiers