GERM vs. IDNA

Last updated Apr 2, 2026

Compare and contrast key facts about Amplify Treatments, Testing and Advancements ETF (GERM) and iShares Genomics Immunology and Healthcare ETF Genomics Immunology and Healthcare Fund (IDNA).

GERM and IDNA are both exchange-traded funds (ETFs), meaning they are traded on stock exchanges and can be bought and sold throughout the day. GERM is a passively managed fund by Amplify that tracks the performance of the Prime Treatments, Testing and Advancements Index. It was launched on Jun 17, 2020. IDNA is a passively managed fund by iShares that tracks the performance of the NYSE FactSet Global Genomics and Immuno Biopharma Index. It was launched on Jun 11, 2019. Both GERM and IDNA are passive ETFs, meaning that they are not actively managed but aim to replicate the performance of the underlying index as closely as possible.

Performance

GERM vs. IDNA - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Amplify Treatments, Testing and Advancements ETF (GERM) and iShares Genomics Immunology and Healthcare ETF Genomics Immunology and Healthcare Fund (IDNA). The values are adjusted to include any dividend payments, if applicable.

GERM vs. IDNA - Yearly Performance Comparison

	2026 (YTD)	2025	2024
GERM Amplify Treatments, Testing and Advancements ETF	0.00%	0.00%	0.00%
IDNA iShares Genomics Immunology and Healthcare ETF Genomics Immunology and Healthcare Fund	11.45%	17.26%	-4.98%

Returns By Period

GERM

• 1D: 0.00%
• 1M: 0.00%
• YTD: 0.00%
• 6M: 0.00%
• 1Y: 0.00%
• 3Y*: —
• 5Y*: —
• 10Y*: —

IDNA

• 1D: 0.48%
• 1M: -5.56%
• YTD: 11.45%
• 6M: 20.68%
• 1Y: 48.06%
• 3Y*: 9.03%
• 5Y*: -7.93%
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

GERM vs. IDNA - Expense Ratio Comparison

GERM has a 0.68% expense ratio, which is higher than IDNA's 0.47% expense ratio.

GERM

Amplify Treatments, Testing and Advancements ETF

IDNA

iShares Genomics Immunology and Healthcare ETF Genomics Immunology and Healthcare Fund

Return for Risk

GERM vs. IDNA — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

IDNA

IDNA Risk / Return Rank: 85
IDNA Sharpe Ratio Rank: 85
IDNA Sortino Ratio Rank: 86
IDNA Omega Ratio Rank: 74
IDNA Calmar Ratio Rank: 93
IDNA Martin Ratio Rank: 88

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

GERM vs. IDNA - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Amplify Treatments, Testing and Advancements ETF (GERM) and iShares Genomics Immunology and Healthcare ETF Genomics Immunology and Healthcare Fund (IDNA). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Risk / return metrics aren't available yet — we need at least 12 months of trading data to calculate them.

Sharpe Ratios by Period

	GERM	IDNA	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	—	1.75	—
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	—	-0.28	—
Sharpe Ratio (All Time) Calculated using the full available price history	—	0.11	—

Dividends

GERM vs. IDNA - Dividend Comparison

GERM has not paid dividends to shareholders, while IDNA's dividend yield for the trailing twelve months is around 1.06%.

	TTM	2025	2024	2023	2022	2021	2020	2019
GERM Amplify Treatments, Testing and Advancements ETF	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%
IDNA iShares Genomics Immunology and Healthcare ETF Genomics Immunology and Healthcare Fund	1.06%	1.18%	0.98%	1.04%	0.54%	0.70%	0.26%	0.80%

Drawdowns

GERM vs. IDNA - Drawdown Comparison

The maximum GERM drawdown since its inception was 0.00%, smaller than the maximum IDNA drawdown of -68.26%. Use the drawdown chart below to compare losses from any high point for GERM and IDNA.

Drawdown Indicators

	GERM	IDNA	Difference
Max Drawdown Largest peak-to-trough decline	0.00%	-68.26%	+68.26%
Max Drawdown (1Y) Largest decline over 1 year	0.00%	-12.11%	+12.11%
Max Drawdown (5Y) Largest decline over 5 years	—	-68.26%	—
Current Drawdown Current decline from peak	0.00%	-45.05%	+45.05%
Average Drawdown Average peak-to-trough decline	0.00%	-36.05%	+36.05%
Ulcer Index Depth and duration of drawdowns from previous peaks	0.00%	3.81%	-3.81%

Volatility

GERM vs. IDNA - Volatility Comparison

The current volatility for Amplify Treatments, Testing and Advancements ETF (GERM) is 0.00%, while iShares Genomics Immunology and Healthcare ETF Genomics Immunology and Healthcare Fund (IDNA) has a volatility of 9.54%. This indicates that GERM experiences smaller price fluctuations and is considered to be less risky than IDNA based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	GERM	IDNA	Difference
Volatility (1M) Calculated over the trailing 1-month period	0.00%	9.54%	-9.54%
Volatility (6M) Calculated over the trailing 6-month period	0.00%	18.22%	-18.22%
Volatility (1Y) Calculated over the trailing 1-year period	0.00%	27.75%	-27.75%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	0.00%	28.53%	-28.53%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	0.00%	29.68%	-29.68%