SPDR S&P Pharmaceuticals ETF (XPH) Alternatives
SPDR S&P Pharmaceuticals ETF (XPH) belongs to the Health & Biotech Equities category. Below you'll find alternative ETFs from the same category, ranked by key criteria, plus funds that investors commonly compare with XPH. Use the tables to find lower-cost options, better risk-adjusted returns, or funds that fit a different role in your portfolio.
Cheapest Alternatives to XPH
XPH charges 0.35% annually. Among ETFs in the Health & Biotech Equities category, these options have the lowest expense ratios among XPH alternatives.
| Symbol | Name | Expense Ratio | Inception | |
|---|---|---|---|---|
| Fidelity MSCI Health Care Index ETF | 0.08% | Oct 21, 2013 | XPH vs FHLC | |
| State Street Health Care Select Sector SPDR ETF | 0.08% | Dec 16, 1998 | XPH vs XLV | |
| Vanguard Health Care ETF | 0.10% | Jan 26, 2004 | XPH vs VHT | |
| Invesco S&P SmallCap Health Care ETF | 0.29% | Apr 7, 2010 | XPH vs PSCH | |
| SPDR S&P Health Care Services ETF | 0.35% | Sep 28, 2011 | XPH vs XHS |
Best Risk-Adjusted Alternatives to XPH
Among ETFs in the Health & Biotech Equities category, these options rank highest on PortfoliosLab's risk-adjusted score, which accounts for volatility, drawdown, and return consistency over a 1-year period.
| Symbol | Name | Risk / Return Rank | Inception | |
|---|---|---|---|---|
| Virtus LifeSci Biotech Clinical Trials ETF | 97 | Dec 16, 2014 | XPH vs BBC | |
| ALPS Medical Breakthroughs ETF | 95 | Dec 31, 2014 | XPH vs SBIO | |
| SPDR S&P Biotech ETF | 92 | Feb 6, 2006 | XPH vs XBI | |
| Tema Oncology ETF | 90 | Aug 14, 2023 | XPH vs CANC | |
| F/m Emerald Life Sciences Innovation ETF | 86 | Oct 30, 2024 | XPH vs LFSC |
Top Performing XPH Alternatives (YTD)
XPH alternatives from the Health & Biotech Equities category, sorted by year-to-date return.
| Symbol | Name | YTD Return | Inception | |
|---|---|---|---|---|
| iShares Genomics Immunology and Healthcare ETF Gen... | 10.92% | Jun 11, 2019 | XPH vs IDNA | |
| Virtus LifeSci Biotech Clinical Trials ETF | 7.95% | Dec 16, 2014 | XPH vs BBC | |
| Tema Oncology ETF | 5.69% | Aug 14, 2023 | XPH vs CANC | |
| SPDR S&P Biotech ETF | 4.76% | Feb 6, 2006 | XPH vs XBI | |
| First Trust Nasdaq Pharmaceuticals ETF | 4.48% | Sep 20, 2016 | XPH vs FTXH |
Lowest Volatility Alternatives to XPH
XPH alternatives from the Health & Biotech Equities category, sorted by annualized volatility over the past year.
| Symbol | Name | Volatility 1Y | Inception | |
|---|---|---|---|---|
| Principal Healthcare Innovators Index ETF | 0.00% | Aug 19, 2016 | XPH vs BTEC | |
| Loncar Cancer Immunotherapy ETF | 0.00% | Oct 13, 2015 | XPH vs CNCR | |
| Amplify Treatments, Testing and Advancements ETF | 0.00% | Jun 17, 2020 | XPH vs GERM | |
| Horizon Kinetics SPAC Active ETF | 8.60% | Jun 29, 2007 | XPH vs SPAQ | |
| Global X Aging Population ETF | 15.94% | May 9, 2016 | XPH vs AGNG |
Lowest Drawdown Alternatives to XPH
XPH alternatives from the Health & Biotech Equities category, sorted by maximum drawdown over the past year.
| Symbol | Name | Max Drawdown 1Y | Inception | |
|---|---|---|---|---|
| Amplify Treatments, Testing and Advancements ETF | 0.00% | Jun 17, 2020 | XPH vs GERM | |
| Horizon Kinetics SPAC Active ETF | -5.30% | Jun 29, 2007 | XPH vs SPAQ | |
| Jpmorgan Healthcare Leaders ETF | -9.68% | Nov 1, 2023 | XPH vs JDOC | |
| VanEck Vectors Pharmaceutical ETF | -10.02% | Dec 20, 2011 | XPH vs PPH | |
| Global X Aging Population ETF | -10.16% | May 9, 2016 | XPH vs AGNG |
Other ETFs from State Street
Most popular State Street ETFs on PortfoliosLab, across asset classes.
| Symbol | Name | Category | Risk / Return Rank | YTD Return | Inception | |
|---|---|---|---|---|---|---|
| State Street SPDR S&P 500 ETF | S&P 500 | 64 | -4.37% | Jan 22, 1993 | XPH vs SPY | |
| SPDR Gold Shares | Gold, Precious Metals | 87 | 8.57% | Nov 18, 2004 | XPH vs GLD | |
| State Street Technology Select Sector SPDR ETF | Technology Equities | 69 | -7.57% | Dec 16, 1998 | XPH vs XLK | |
| State Street SPDR Portfolio S&P 500 Growth ETF | S&P 500, Large Cap Growth Equities | 66 | -8.12% | Sep 25, 2000 | XPH vs SPYG | |
| SPDR Portfolio S&P 500 High Dividend ETF | S&P 500, Dividend | 30 | 6.32% | Oct 21, 2015 | XPH vs SPYD | |
| SPDR Gold MiniShares Trust | Precious Metals, Gold | 88 | 8.57% | Jun 25, 2018 | XPH vs GLDM | |
| State Street Energy Select Sector SPDR ETF | Energy Equities | 73 | 37.91% | Dec 16, 1998 | XPH vs XLE | |
| Utilities Select Sector SPDR Fund | Utilities Equities | 71 | 8.25% | Dec 16, 1998 | XPH vs XLU | |
| SPDR Barclays 1-3 Month T-Bill ETF | Government Bonds | 100 | 0.85% | May 25, 2007 | XPH vs BIL | |
| SPDR Dow Jones Industrial Average ETF | Large Cap Growth Equities | 47 | -3.25% | Jan 14, 1998 | XPH vs DIA |
Often Compared With XPH
What investors most often compare with XPH, based on PortfoliosLab usage data.
Compare XPH with Any Fund or Stock
Compare XPH with any ETF, mutual fund, or stock using PortfoliosLab's comparison tool.