XPH vs. CNCR

Last updated Apr 2, 2026

Compare and contrast key facts about SPDR S&P Pharmaceuticals ETF (XPH) and Loncar Cancer Immunotherapy ETF (CNCR).

XPH and CNCR are both exchange-traded funds (ETFs), meaning they are traded on stock exchanges and can be bought and sold throughout the day. XPH is a passively managed fund by State Street that tracks the performance of the S&P Pharmaceuticals Select Industry Index. It was launched on Jun 19, 2006. CNCR is a passively managed fund by Exchange Traded Concepts that tracks the performance of the Loncar Cancer Immunotherapy Index. It was launched on Oct 13, 2015. Both XPH and CNCR are passive ETFs, meaning that they are not actively managed but aim to replicate the performance of the underlying index as closely as possible.

Performance

XPH vs. CNCR - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in SPDR S&P Pharmaceuticals ETF (XPH) and Loncar Cancer Immunotherapy ETF (CNCR). The values are adjusted to include any dividend payments, if applicable.

XPH vs. CNCR - Yearly Performance Comparison

	2026 (YTD)
XPH SPDR S&P Pharmaceuticals ETF	-4.34%
CNCR Loncar Cancer Immunotherapy ETF	0.00%

Returns By Period

XPH

• 1D: 1.16%
• 1M: -4.82%
• YTD: -2.19%
• 6M: 13.09%
• 1Y: 30.74%
• 3Y*: 11.47%
• 5Y*: 3.03%
• 10Y*: 3.94%

CNCR

• 1D: 0.00%
• 1M: 0.00%
• YTD: —
• 6M: —
• 1Y: —
• 3Y*: —
• 5Y*: —
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

XPH vs. CNCR - Expense Ratio Comparison

XPH has a 0.35% expense ratio, which is lower than CNCR's 0.79% expense ratio.

CNCR

Loncar Cancer Immunotherapy ETF

XPH

SPDR S&P Pharmaceuticals ETF

Return for Risk

XPH vs. CNCR — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

XPH

XPH Risk / Return Rank: 66
XPH Sharpe Ratio Rank: 69
XPH Sortino Ratio Rank: 69
XPH Omega Ratio Rank: 59
XPH Calmar Ratio Rank: 72
XPH Martin Ratio Rank: 62

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

XPH vs. CNCR - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for SPDR S&P Pharmaceuticals ETF (XPH) and Loncar Cancer Immunotherapy ETF (CNCR). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	XPH	CNCR	Difference
Sharpe ratio Return per unit of total volatility	1.28	—	—
Sortino ratio Return per unit of downside risk	1.80	—	—
Omega ratio Gain probability vs. loss probability	1.23	—	—
Calmar ratio Return relative to maximum drawdown	1.97	—	—
Martin ratio Return relative to average drawdown	6.54	—	—
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

Sharpe Ratios by Period

	XPH	CNCR	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	1.28	—	—
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	0.15	—	—
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	0.18	—	—
Sharpe Ratio (All Time) Calculated using the full available price history	0.38	—	—

Dividends

XPH vs. CNCR - Dividend Comparison

XPH's dividend yield for the trailing twelve months is around 0.68%, while CNCR has not paid dividends to shareholders.

	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
XPH SPDR S&P Pharmaceuticals ETF	0.68%	0.83%	1.58%	1.28%	1.64%	0.95%	0.47%	0.64%	0.65%	0.67%	0.63%	7.15%
CNCR Loncar Cancer Immunotherapy ETF	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%

Drawdowns

XPH vs. CNCR - Drawdown Comparison

The maximum XPH drawdown since its inception was -48.03%, which is greater than CNCR's maximum drawdown of 0.00%. Use the drawdown chart below to compare losses from any high point for XPH and CNCR.

Drawdown Indicators

	XPH	CNCR	Difference
Max Drawdown Largest peak-to-trough decline	-48.03%	0.00%	-48.03%
Max Drawdown (1Y) Largest decline over 1 year	-13.15%	—	—
Max Drawdown (5Y) Largest decline over 5 years	-31.63%	—	—
Max Drawdown (10Y) Largest decline over 10 years	-35.97%	—	—
Current Drawdown Current decline from peak	-6.21%	0.00%	-6.21%
Average Drawdown Average peak-to-trough decline	-17.37%	0.00%	-17.37%
Ulcer Index Depth and duration of drawdowns from previous peaks	3.96%	—	—

Volatility

Volatility by Period

	XPH	CNCR	Difference
Volatility (1M) Calculated over the trailing 1-month period	9.05%	—	—
Volatility (6M) Calculated over the trailing 6-month period	16.40%	—	—
Volatility (1Y) Calculated over the trailing 1-year period	24.50%	0.00%	+24.50%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	20.57%	0.00%	+20.57%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	22.22%	0.00%	+22.22%