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Performance
Performance Chart
The chart shows the growth of an initial investment of $10,000 in Janus Henderson Global Life Sciences Fund Class T, comparing it to the performance of the S&P 500 index or another benchmark. All prices have been adjusted for splits and dividends.
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Returns By Period
Janus Henderson Global Life Sciences Fund Class T (JAGLX) has returned -6.63% so far this year and 15.33% over the past 12 months. Over the last ten years, JAGLX has returned 11.21% per year, falling short of the S&P 500 Index benchmark, which averaged 12.16% annually.
Janus Henderson Global Life Sciences Fund Class T
- 1D
- 0.31%
- 1M
- -9.20%
- YTD
- -6.63%
- 6M
- 10.77%
- 1Y
- 15.33%
- 3Y*
- 11.20%
- 5Y*
- 7.66%
- 10Y*
- 11.21%
Benchmark (S&P 500 Index)
- 1D
- 2.91%
- 1M
- -5.09%
- YTD
- -4.63%
- 6M
- -2.39%
- 1Y
- 16.33%
- 3Y*
- 16.69%
- 5Y*
- 10.18%
- 10Y*
- 12.16%
Monthly Returns
Based on dividend-adjusted daily data since Dec 31, 1998, JAGLX's average daily return is +0.05%, while the average monthly return is +1.05%. At this rate, your investment would double in approximately 5.5 years.
Historically, 62% of months were positive and 38% were negative. The best month was Feb 2000 with a return of +40.8%, while the worst month was Mar 2000 at -29.5%. The longest winning streak lasted 15 consecutive months, and the longest losing streak was 6 months.
On a daily basis, JAGLX closed higher 53% of trading days. The best single day was Oct 13, 2008 with a return of +11.7%, while the worst single day was Mar 16, 2020 at -10.4%.
| Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec | Total | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2026 | 0.77% | 2.05% | -9.20% | -6.63% | |||||||||
| 2025 | 5.93% | -0.22% | -4.46% | -0.31% | -5.70% | 2.33% | -0.87% | 6.13% | 2.87% | 8.70% | 9.27% | -0.12% | 24.72% |
| 2024 | 2.75% | 3.84% | 1.72% | -4.65% | 3.56% | 3.20% | 2.66% | 5.17% | -2.41% | -3.30% | -0.71% | -3.01% | 8.50% |
| 2023 | 0.48% | -4.33% | 2.68% | 4.02% | -2.32% | 2.98% | 1.01% | -1.39% | -3.75% | -6.12% | 7.42% | 7.57% | 7.41% |
| 2022 | -9.06% | 0.57% | 3.59% | -6.71% | -0.92% | -0.78% | 3.66% | -2.55% | -2.88% | 8.53% | 6.01% | -0.89% | -2.79% |
| 2021 | -0.84% | 0.07% | -1.93% | 3.11% | 0.25% | 3.57% | 0.15% | 3.19% | -4.08% | 4.49% | -7.40% | 6.75% | 6.66% |
Benchmark Metrics
Janus Henderson Global Life Sciences Fund Class T has an annualized alpha of 6.71%, beta of 0.77, and R² of 0.57 versus S&P 500 Index. Calculated based on daily prices since January 04, 1999.
- This fund participates in less of S&P 500 Index's moves in both directions, but captures a larger share of gains (87.19%) than losses (64.61%) — typical of diversified or defensive assets.
- This fund generated an annualized alpha of 6.71% versus S&P 500 Index — delivering returns beyond what market exposure alone would predict.
- Alpha
- 6.71%
- Beta
- 0.77
- R²
- 0.57
- Upside Capture
- 87.19%
- Downside Capture
- 64.61%
Expense Ratio
JAGLX has an expense ratio of 0.92%, placing it in the medium range.
Return for Risk
Risk / Return Rank
JAGLX ranks 36 for risk / return — below 36% of mutual funds on our site. The returns aren't fully compensating for the risk involved. This isn't necessarily a dealbreaker, but factor it into your decision — especially if you're risk-averse.
Return / Risk — by metrics
The table below present risk-adjusted performance metrics for Janus Henderson Global Life Sciences Fund Class T (JAGLX) and compare them to a chosen benchmark (S&P 500 Index).
| JAGLX | Benchmark | Difference | |
|---|---|---|---|
Sharpe ratioReturn per unit of total volatility | 0.82 | 0.90 | -0.08 |
Sortino ratioReturn per unit of downside risk | 1.21 | 1.39 | -0.18 |
Omega ratioGain probability vs. loss probability | 1.16 | 1.21 | -0.05 |
Calmar ratioReturn relative to maximum drawdown | 1.28 | 1.40 | -0.12 |
Martin ratioReturn relative to average drawdown | 3.45 | 6.61 | -3.16 |
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month. | |||
Explore JAGLX risk-adjusted metrics in detail
Dive deeper into individual metrics with historical trends, benchmark comparisons, and performance across different time periods.
Dividends
Dividend History
Janus Henderson Global Life Sciences Fund Class T provided a 4.85% dividend yield over the last twelve months, with an annual payout of $3.64 per share.
| Period | TTM | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dividend | $3.64 | $3.64 | $7.41 | $2.90 | $0.09 | $6.73 | $5.50 | $3.77 | $6.72 | $0.48 | $0.51 | $4.74 |
Dividend yield | 4.85% | 4.53% | 10.98% | 4.22% | 0.14% | 9.78% | 7.75% | 6.17% | 13.38% | 0.89% | 1.13% | 9.09% |
Monthly Dividends
The table displays the monthly dividend distributions for Janus Henderson Global Life Sciences Fund Class T. The dividends shown in the table have been adjusted to account for any splits that may have occurred.
| Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec | Total | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2026 | $0.00 | $0.00 | $0.00 | $0.00 | |||||||||
| 2025 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $3.64 | $3.64 |
| 2024 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $7.41 | $7.41 |
| 2023 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $2.90 | $2.90 |
| 2022 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.09 | $0.09 |
| 2021 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $6.73 | $6.73 |
Drawdowns
Drawdowns Chart
The Drawdowns chart displays portfolio losses from any high point along the way. Drawdowns are calculated considering price movements and all distributions paid, if any.
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Worst Drawdowns
The table below displays the maximum drawdowns of the Janus Henderson Global Life Sciences Fund Class T. A maximum drawdown is a measure of risk, indicating the largest reduction in portfolio value due to a series of losing trades.
The maximum drawdown for the Janus Henderson Global Life Sciences Fund Class T was 58.96%, occurring on Feb 13, 2003. Recovery took 2290 trading sessions.
The current Janus Henderson Global Life Sciences Fund Class T drawdown is 9.43%.
Depth | Start | To Bottom | Bottom | To Recover | End | Total |
|---|---|---|---|---|---|---|
| -58.96% | Mar 6, 2000 | 739 | Feb 13, 2003 | 2290 | Mar 19, 2012 | 3029 |
| -30.84% | Jul 21, 2015 | 140 | Feb 8, 2016 | 495 | Jan 25, 2018 | 635 |
| -27.38% | Feb 20, 2020 | 23 | Mar 23, 2020 | 49 | Jun 2, 2020 | 72 |
| -22.25% | Nov 4, 2021 | 155 | Jun 16, 2022 | 384 | Dec 27, 2023 | 539 |
| -18.68% | Oct 1, 2018 | 59 | Dec 24, 2018 | 70 | Apr 5, 2019 | 129 |
Volatility
Volatility Chart
The chart below shows the rolling one-month volatility.
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