XPH vs. GERM

Last updated Jun 4, 2026

XPH (SPDR S&P Pharmaceuticals ETF) and GERM (Amplify Treatments, Testing and Advancements ETF) are both Health & Biotech Equities funds - XPH tracks the S&P Pharmaceuticals Select Industry Index while GERM tracks the Prime Treatments, Testing and Advancements Index. Both are passively managed. Over the past year, XPH returned 37.98% vs 0.00% for GERM. XPH charges 0.35%/yr vs 0.68%/yr for GERM.

Performance

XPH vs. GERM - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in SPDR S&P Pharmaceuticals ETF (XPH) and Amplify Treatments, Testing and Advancements ETF (GERM). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

XPH

• 1D: 1.10%
• 1M: -4.74%
• YTD: 0.66%
• 6M: 4.44%
• 1Y: 37.98%
• 3Y*: 13.07%
• 5Y*: 3.50%
• 10Y*: 3.44%

GERM

• 1D: 0.00%
• 1M: 0.00%
• YTD: 0.00%
• 6M: 0.00%
• 1Y: 0.00%
• 3Y*: —
• 5Y*: —
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

XPH vs. GERM - Yearly Performance Comparison

	2026 (YTD)	2025	2024
XPH SPDR S&P Pharmaceuticals ETF	0.66%	31.60%	0.00%
GERM Amplify Treatments, Testing and Advancements ETF	0.00%	0.00%	0.00%

XPH vs. GERM - Sectors Allocation Comparison

Sectors	XPH	GERM
Healthcare	100.0%	99.3%
Basic Materials	-	-
Communication Services	-	-
Consumer Cyclical	-	-
Consumer Defensive	-	-
Energy	-	-
Financial Services	-	0.4%
Industrials	-	-
Real Estate	-	-
Technology	-	-
Utilities	-	-

Return for Risk

XPH vs. GERM — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

XPH

XPH Risk / Return Rank: 55
XPH Sharpe Ratio Rank: 51
XPH Sortino Ratio Rank: 51
XPH Omega Ratio Rank: 46
XPH Calmar Ratio Rank: 64
XPH Martin Ratio Rank: 63

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

XPH vs. GERM - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for SPDR S&P Pharmaceuticals ETF (XPH) and Amplify Treatments, Testing and Advancements ETF (GERM). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	XPH	GERM	Difference
Sharpe ratio: Return per unit of total volatility	1.77	—	—
Sortino ratio: Return per unit of downside risk	2.51	—	—
Omega ratio: Gain probability vs. loss probability	1.30	—	—
Calmar ratio: Return relative to maximum drawdown	3.19	—	—
Martin ratio: Return relative to average drawdown	11.37	—	—
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

Sharpe Ratios by Period

	XPH	GERM	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	1.77	—	—
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	0.17	—	—
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	0.16	—	—
Sharpe Ratio (All Time) Calculated using the full available price history	0.38	—	—

Drawdowns

XPH vs. GERM - Drawdown Comparison

The maximum XPH drawdown since its inception was -48.03%, which is greater than GERM's maximum drawdown of 0.00%. Use the drawdown chart below to compare losses from any high point for XPH and GERM.

Drawdown Indicators

	XPH	GERM	Difference
Max Drawdown Largest peak-to-trough decline	-48.03%	0.00%	-48.03%
Max Drawdown (1Y) Largest decline over 1 year	-11.97%	0.00%	-11.97%
Max Drawdown (3Y) Largest decline over 3 years	-23.57%	—	—
Max Drawdown (5Y) Largest decline over 5 years	-31.63%	—	—
Max Drawdown (10Y) Largest decline over 10 years	-35.97%	—	—
Current Drawdown Current decline from peak	-7.22%	0.00%	-7.22%
Average Drawdown Average peak-to-trough decline	-17.25%	0.00%	-17.25%
Ulcer Index Depth and duration of drawdowns from previous peaks	3.35%	0.00%	+3.35%

Volatility

XPH vs. GERM - Volatility Comparison

SPDR S&P Pharmaceuticals ETF (XPH) has a higher volatility of 7.03% compared to Amplify Treatments, Testing and Advancements ETF (GERM) at 0.00%. This indicates that XPH's price experiences larger fluctuations and is considered to be riskier than GERM based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	XPH	GERM	Difference
Volatility (1M) Calculated over the trailing 1-month period	7.03%	0.00%	+7.03%
Volatility (6M) Calculated over the trailing 6-month period	16.77%	0.00%	+16.77%
Volatility (1Y) Calculated over the trailing 1-year period	21.52%	0.00%	+21.52%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	20.84%	0.00%	+20.84%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	22.10%	0.00%	+22.10%

XPH vs. GERM - Expense Ratio Comparison

XPH has a 0.35% expense ratio, which is lower than GERM's 0.68% expense ratio.

Dividends

XPH vs. GERM - Dividend Comparison

XPH's dividend yield for the trailing twelve months is around 0.66%, while GERM has not paid dividends to shareholders.

Position	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
GERM Amplify Treatments, Testing and Advancements ETF	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%
XPH SPDR S&P Pharmaceuticals ETF	0.66%	0.83%	1.58%	1.28%	1.64%	0.95%	0.47%	0.64%	0.65%	0.67%	0.63%	7.15%

Frequently Asked Questions

Which is riskier, XPH or GERM?

XPH has higher volatility (7.03%) compared to GERM (0.00%). In terms of maximum drawdown, XPH dropped -48.03% vs GERM's 0.00%.

Which ETF is better, XPH or GERM?

On 1-year performance, XPH leads with 37.98% vs 0.00% for GERM. On fees, XPH is cheaper at 0.35% per year. On volatility, GERM has been the lower-risk option at 0.00%. The better choice depends on whether you care most about return, fees, risk, or income.

Which ETF has performed better, XPH or GERM?

Over the 1-year period, XPH has performed better with a 37.98% return vs 0.00%. Past performance does not guarantee future results, so compare this with risk, fees, and fund exposure.

Which ETF is cheaper, XPH or GERM?

XPH is cheaper with a 0.35% expense ratio, compared with 0.68% for GERM.

Which ETF pays a higher dividend yield, XPH or GERM?

XPH has the higher dividend yield at 0.66%, compared with 0.00% for GERM.

What is the main difference between XPH and GERM?

XPH tracks S&P Pharmaceuticals Select Industry Index, while GERM tracks Prime Treatments, Testing and Advancements Index. They also come from different issuers: State Street and Amplify. Their fees differ too: 0.35% for XPH and 0.68% for GERM.