Global X HealthTech ETF (HEAL) belongs to the Health & Biotech Equities category. Below you'll find alternative ETFs from the same category, ranked by key criteria, plus funds that investors commonly compare with HEAL. Use the tables to find lower-cost options, better risk-adjusted returns, or a closer substitute for your current allocation.
Cheapest Alternatives to HEAL
HEAL charges 0.50% annually. There are 24 ETFs in the Health & Biotech Equities category with lower expense ratios, going as low as 0.08%.
| Symbol | Name | Expense Ratio | AUM | Inception | |
|---|---|---|---|---|---|
| Fidelity MSCI Health Care Index ETF | 0.08% | 2.99B | Oct 2013 | HEAL vs FHLC | |
| State Street Health Care Select Sector SPDR ETF | 0.08% | 38.47B | Dec 1998 | HEAL vs XLV | |
| Vanguard Health Care ETF | 0.09% | 19.00B | Jan 2004 | HEAL vs VHT | |
| Portfolio Building Block World Pharma and Biotech ... | 0.13% | 9.98M | Nov 2025 | HEAL vs PBPH | |
| GSK plc ADRhedged ETF | 0.19% | 793.18K | Jan 2025 | HEAL vs GSKH |
Best Risk-Adjusted Alternatives to HEAL
HEAL has a PortfoliosLab risk / return rank of 4. There are 54 ETFs in the Health & Biotech Equities category with higher risk-adjusted ranks, going as high as 95.
| Symbol | Name | Risk / Return Rank | AUM | Inception | |
|---|---|---|---|---|---|
| Virtus LifeSci Biotech Clinical Trials ETF | 95 | 40.93M | Dec 2014 | HEAL vs BBC | |
| ALPS Medical Breakthroughs ETF | 93 | 160.12M | Dec 2014 | HEAL vs SBIO | |
| SPDR S&P Biotech ETF | 92 | 8.62B | Feb 2006 | HEAL vs XBI | |
| iShares Neuroscience and Healthcare ETF | 90 | 5.39M | Aug 2022 | HEAL vs IBRN | |
| iShares U.S. Pharmaceuticals ETF | 89 | 956.44M | May 2006 | HEAL vs IHE |
Top Performing HEAL Alternatives (YTD)
HEAL is at -8.68% YTD. There are 59 ETFs in the Health & Biotech Equities category with higher YTD returns, going as high as 33.17%.
| Symbol | Name | YTD Return | AUM | Inception | |
|---|---|---|---|---|---|
| ARK Genomic Revolution Multi-Sector ETF | 33.17% | 1.31B | Oct 2014 | HEAL vs ARKG | |
| Virtus LifeSci Biotech Clinical Trials ETF | 27.49% | 40.93M | Dec 2014 | HEAL vs BBC | |
| AdvisorShares Psychedelics ETF | 26.51% | 33.07M | Sep 2021 | HEAL vs PSIL | |
| Roundhill UNH WeeklyPay ETF | 25.93% | 4.79M | Dec 2025 | HEAL vs UNHW | |
| SPDR S&P Biotech ETF | 22.90% | 8.62B | Feb 2006 | HEAL vs XBI |
Lowest Volatility Alternatives to HEAL
HEAL has 22.40% 1-year volatility. There are 42 ETFs in the Health & Biotech Equities category with lower 1-year volatility, going as low as 0.00%.
| Symbol | Name | Volatility 1Y | AUM | Inception | |
|---|---|---|---|---|---|
| Amplify Treatments, Testing and Advancements ETF | 0.00% | 9.68M | Jun 2020 | HEAL vs GERM | |
| Loncar Cancer Immunotherapy ETF | 0.00% | 12.73M | Oct 2015 | HEAL vs CNCR | |
| Horizon Kinetics SPAC Active ETF | 8.62% | 10.10M | Jun 2007 | HEAL vs SPAQ | |
| State Street Health Care Select Sector SPDR Premiu... | 11.05% | 14.95M | Jul 2025 | HEAL vs XLVI | |
| Global X Aging Population ETF | 13.75% | 80.19M | May 2016 | HEAL vs AGNG |
Lowest Drawdown Alternatives to HEAL
HEAL has a 1-year max drawdown of -30.71%. There are 55 ETFs in the Health & Biotech Equities category with shallower 1-year drawdowns, going as shallow as 0.00%.
| Symbol | Name | Max Drawdown 1Y | AUM | Inception | |
|---|---|---|---|---|---|
| Amplify Treatments, Testing and Advancements ETF | 0.00% | 9.68M | Jun 2020 | HEAL vs GERM | |
| Horizon Kinetics SPAC Active ETF | -4.60% | 10.10M | Jun 2007 | HEAL vs SPAQ | |
| First Trust Nasdaq Pharmaceuticals ETF | -7.47% | 33.60M | Sep 2016 | HEAL vs FTXH | |
| Invesco Nasdaq Biotechnology ETF | -8.34% | 68.94M | Jun 2021 | HEAL vs IBBQ | |
| iShares U.S. Pharmaceuticals ETF | -8.47% | 956.44M | May 2006 | HEAL vs IHE |
Other ETFs from Global X
The 10 most viewed Global X ETFs shown here include QYLD, SHLD, AIQ and span 12 categories. AUM among these funds goes as high as $14B.
| Symbol | Name | Category | Risk / Return Rank | YTD Return | AUM | Inception | |
|---|---|---|---|---|---|---|---|
| Global X NASDAQ 100 Covered Call ETF | Nasdaq-100, Derivative Income | 85 | 7.65% | 8.44B | Dec 2013 | HEAL vs QYLD | |
| Global X Defense Tech ETF | Aerospace & Defense | 10 | -9.12% | 7.43B | Sep 2023 | HEAL vs SHLD | |
| Global X Artificial Intelligence & Technology ETF | Technology Equities | 58 | 24.64% | 11.08B | May 2018 | HEAL vs AIQ | |
| Global X Uranium ETF | Uranium | 17 | 4.66% | 6.64B | Nov 2010 | HEAL vs URA | |
| Global X Copper Miners ETF | Copper | 56 | 5.45% | 8.06B | Apr 2010 | HEAL vs COPX | |
| Global X Robotics & Artificial Intelligence Themat... | Robotics, Technology Equities | 21 | 0.97% | 3.54B | Sep 2016 | HEAL vs BOTZ | |
| Global X Silver Miners ETF | Silver, Precious Metals | 34 | -9.52% | 4.57B | Apr 2010 | HEAL vs SIL | |
| Global X S&P 500 Covered Call ETF | Derivative Income, S&P 500 | 80 | 4.51% | 3.19B | Jun 2013 | HEAL vs XYLD | |
| Global X Data Center & Digital Infrastructure ETF | REIT | 89 | 47.11% | 2.37B | Oct 2020 | HEAL vs DTCR | |
| Global X US Infrastructure Development ETF | Industrials Equities | 64 | 22.22% | 14.28B | Mar 2017 | HEAL vs PAVE |
Often Compared With HEAL
Investors most often compare HEAL with HTEC, DFEN, IBB. These 20 comparison targets span 10 categories, based on PortfoliosLab usage data.
Compare HEAL with Any Fund or Stock
Compare HEAL with any ETF, mutual fund, or stock using PortfoliosLab's comparison tool.
Pair HEAL with funds that move differently
Global X HealthTech ETF alternatives help with substitution. Diversifiers are the next step when you want funds with lower historical correlation to HEAL.
Explore HEAL Diversifiers