ALPS Medical Breakthroughs ETF (SBIO) Alternatives
ALPS Medical Breakthroughs ETF (SBIO) belongs to the Health & Biotech Equities category. Below you'll find alternative ETFs from the same category, ranked by key criteria, plus funds that investors commonly compare with SBIO. Use the tables to find lower-cost options, better risk-adjusted returns, or funds that fit a different role in your portfolio.
Cheapest Alternatives to SBIO
SBIO charges 0.50% annually. Among ETFs in the Health & Biotech Equities category, these options have the lowest expense ratios among SBIO alternatives.
| Symbol | Name | Expense Ratio | Inception | |
|---|---|---|---|---|
| Fidelity MSCI Health Care Index ETF | 0.08% | Oct 21, 2013 | SBIO vs FHLC | |
| State Street Health Care Select Sector SPDR ETF | 0.08% | Dec 16, 1998 | SBIO vs XLV | |
| Vanguard Health Care ETF | 0.10% | Jan 26, 2004 | SBIO vs VHT | |
| Invesco S&P SmallCap Health Care ETF | 0.29% | Apr 7, 2010 | SBIO vs PSCH | |
| VanEck Vectors Biotech ETF | 0.35% | Dec 20, 2011 | SBIO vs BBH |
Best Risk-Adjusted Alternatives to SBIO
Among ETFs in the Health & Biotech Equities category, these options rank highest on PortfoliosLab's risk-adjusted score, which accounts for volatility, drawdown, and return consistency over a 1-year period.
| Symbol | Name | Risk / Return Rank | Inception | |
|---|---|---|---|---|
| Virtus LifeSci Biotech Clinical Trials ETF | 98 | Dec 16, 2014 | SBIO vs BBC | |
| SPDR S&P Biotech ETF | 93 | Feb 6, 2006 | SBIO vs XBI | |
| Tema Oncology ETF | 92 | Aug 14, 2023 | SBIO vs CANC | |
| Invesco Nasdaq Biotechnology ETF | 88 | Jun 11, 2021 | SBIO vs IBBQ | |
| iShares Neuroscience and Healthcare ETF | 87 | Aug 24, 2022 | SBIO vs IBRN |
Top Performing SBIO Alternatives (YTD)
SBIO alternatives from the Health & Biotech Equities category, sorted by year-to-date return.
| Symbol | Name | YTD Return | Inception | |
|---|---|---|---|---|
| iShares Genomics Immunology and Healthcare ETF Gen... | 11.45% | Jun 11, 2019 | SBIO vs IDNA | |
| Virtus LifeSci Biotech Clinical Trials ETF | 10.01% | Dec 16, 2014 | SBIO vs BBC | |
| Tema Oncology ETF | 6.91% | Aug 14, 2023 | SBIO vs CANC | |
| SPDR S&P Biotech ETF | 5.43% | Feb 6, 2006 | SBIO vs XBI | |
| First Trust Nasdaq Pharmaceuticals ETF | 5.20% | Sep 20, 2016 | SBIO vs FTXH |
Lowest Volatility Alternatives to SBIO
SBIO alternatives from the Health & Biotech Equities category, sorted by annualized volatility over the past year.
| Symbol | Name | Volatility 1Y | Inception | |
|---|---|---|---|---|
| Principal Healthcare Innovators Index ETF | 0.00% | Aug 19, 2016 | SBIO vs BTEC | |
| Loncar Cancer Immunotherapy ETF | 0.00% | Oct 13, 2015 | SBIO vs CNCR | |
| Amplify Treatments, Testing and Advancements ETF | 0.00% | Jun 17, 2020 | SBIO vs GERM | |
| Horizon Kinetics SPAC Active ETF | 8.59% | Jun 29, 2007 | SBIO vs SPAQ | |
| Global X Aging Population ETF | 15.99% | May 9, 2016 | SBIO vs AGNG |
Lowest Drawdown Alternatives to SBIO
SBIO alternatives from the Health & Biotech Equities category, sorted by maximum drawdown over the past year.
| Symbol | Name | Max Drawdown 1Y | Inception | |
|---|---|---|---|---|
| Amplify Treatments, Testing and Advancements ETF | 0.00% | Jun 17, 2020 | SBIO vs GERM | |
| Horizon Kinetics SPAC Active ETF | -5.30% | Jun 29, 2007 | SBIO vs SPAQ | |
| Jpmorgan Healthcare Leaders ETF | -9.68% | Nov 1, 2023 | SBIO vs JDOC | |
| VanEck Vectors Pharmaceutical ETF | -10.02% | Dec 20, 2011 | SBIO vs PPH | |
| Global X Aging Population ETF | -10.16% | May 9, 2016 | SBIO vs AGNG |
Other ETFs from SS&C
Most popular SS&C ETFs on PortfoliosLab, across asset classes.
| Symbol | Name | Category | Risk / Return Rank | YTD Return | Inception | |
|---|---|---|---|---|---|---|
| Alerian MLP ETF | MLPs | 25 | 13.01% | Aug 23, 2010 | SBIO vs AMLP | |
| Alerian Energy Infrastructure ETF | Energy Equities | 52 | 20.63% | Nov 1, 2013 | SBIO vs ENFR | |
| Alps Equal Sector Weight ETF | Large Cap Blend Equities | 57 | 3.18% | Jul 7, 2009 | SBIO vs EQL | |
| ALPS Sector Dividend Dogs ETF | Large Cap Value Equities, Dividend | 52 | 8.31% | Jun 29, 2012 | SBIO vs SDOG | |
| ALPS Clean Energy ETF | Alternative Energy Equities | 70 | 3.83% | Jun 29, 2018 | SBIO vs ACES | |
| ALPS International Sector Dividend Dogs ETF | Foreign Large Cap Equities, Dividend | 93 | 9.20% | Jun 27, 2013 | SBIO vs IDOG | |
| ALPS REIT Dividend Dogs ETF | REIT, Dividend | 14 | 0.59% | May 7, 2008 | SBIO vs RDOG | |
| ALPS Barron's 400 ETF | Mid Cap Blend Equities | 59 | 1.68% | Jun 4, 2013 | SBIO vs BFOR | |
| ALPS Disruptive Technologies ETF | Technology Equities | 11 | -10.73% | Dec 29, 2017 | SBIO vs DTEC | |
| ALPS Emerging Sector Dividend Dogs ETF | Emerging Markets Equities, Dividend | 79 | 6.22% | Mar 28, 2014 | SBIO vs EDOG |
Often Compared With SBIO
What investors most often compare with SBIO, based on PortfoliosLab usage data.
Compare SBIO with Any Fund or Stock
Compare SBIO with any ETF, mutual fund, or stock using PortfoliosLab's comparison tool.