First Trust Indxx Medical Devices ETF (MDEV) Alternatives
First Trust Indxx Medical Devices ETF (MDEV) belongs to the Health & Biotech Equities category. Below you'll find alternative ETFs from the same category, ranked by key criteria, plus funds that investors commonly compare with MDEV. Use the tables to find lower-cost options, better risk-adjusted returns, or funds that fit a different role in your portfolio.
Cheapest Alternatives to MDEV
MDEV charges 0.70% annually. Among ETFs in the Health & Biotech Equities category, these options have the lowest expense ratios among MDEV alternatives.
| Symbol | Name | Expense Ratio | Inception | |
|---|---|---|---|---|
| Fidelity MSCI Health Care Index ETF | 0.08% | Oct 21, 2013 | MDEV vs FHLC | |
| State Street Health Care Select Sector SPDR ETF | 0.08% | Dec 16, 1998 | MDEV vs XLV | |
| Vanguard Health Care ETF | 0.10% | Jan 26, 2004 | MDEV vs VHT | |
| Invesco S&P SmallCap Health Care ETF | 0.29% | Apr 7, 2010 | MDEV vs PSCH | |
| SPDR S&P Pharmaceuticals ETF | 0.35% | Jun 19, 2006 | MDEV vs XPH |
Best Risk-Adjusted Alternatives to MDEV
Among ETFs in the Health & Biotech Equities category, these options rank highest on PortfoliosLab's risk-adjusted score, which accounts for volatility, drawdown, and return consistency over a 1-year period.
| Symbol | Name | Risk / Return Rank | Inception | |
|---|---|---|---|---|
| Virtus LifeSci Biotech Clinical Trials ETF | 97 | Dec 16, 2014 | MDEV vs BBC | |
| ALPS Medical Breakthroughs ETF | 95 | Dec 31, 2014 | MDEV vs SBIO | |
| SPDR S&P Biotech ETF | 92 | Feb 6, 2006 | MDEV vs XBI | |
| Tema Oncology ETF | 90 | Aug 14, 2023 | MDEV vs CANC | |
| F/m Emerald Life Sciences Innovation ETF | 86 | Oct 30, 2024 | MDEV vs LFSC |
Top Performing MDEV Alternatives (YTD)
MDEV alternatives from the Health & Biotech Equities category, sorted by year-to-date return.
| Symbol | Name | YTD Return | Inception | |
|---|---|---|---|---|
| iShares Genomics Immunology and Healthcare ETF Gen... | 10.92% | Jun 11, 2019 | MDEV vs IDNA | |
| Virtus LifeSci Biotech Clinical Trials ETF | 7.95% | Dec 16, 2014 | MDEV vs BBC | |
| Tema Oncology ETF | 5.69% | Aug 14, 2023 | MDEV vs CANC | |
| SPDR S&P Biotech ETF | 4.76% | Feb 6, 2006 | MDEV vs XBI | |
| First Trust Nasdaq Pharmaceuticals ETF | 4.48% | Sep 20, 2016 | MDEV vs FTXH |
Lowest Volatility Alternatives to MDEV
MDEV alternatives from the Health & Biotech Equities category, sorted by annualized volatility over the past year.
| Symbol | Name | Volatility 1Y | Inception | |
|---|---|---|---|---|
| Principal Healthcare Innovators Index ETF | 0.00% | Aug 19, 2016 | MDEV vs BTEC | |
| Loncar Cancer Immunotherapy ETF | 0.00% | Oct 13, 2015 | MDEV vs CNCR | |
| Amplify Treatments, Testing and Advancements ETF | 0.00% | Jun 17, 2020 | MDEV vs GERM | |
| Horizon Kinetics SPAC Active ETF | 8.60% | Jun 29, 2007 | MDEV vs SPAQ | |
| Global X Aging Population ETF | 15.94% | May 9, 2016 | MDEV vs AGNG |
Lowest Drawdown Alternatives to MDEV
MDEV alternatives from the Health & Biotech Equities category, sorted by maximum drawdown over the past year.
| Symbol | Name | Max Drawdown 1Y | Inception | |
|---|---|---|---|---|
| Amplify Treatments, Testing and Advancements ETF | 0.00% | Jun 17, 2020 | MDEV vs GERM | |
| Horizon Kinetics SPAC Active ETF | -5.30% | Jun 29, 2007 | MDEV vs SPAQ | |
| Jpmorgan Healthcare Leaders ETF | -9.68% | Nov 1, 2023 | MDEV vs JDOC | |
| VanEck Vectors Pharmaceutical ETF | -10.02% | Dec 20, 2011 | MDEV vs PPH | |
| Global X Aging Population ETF | -10.16% | May 9, 2016 | MDEV vs AGNG |
Other ETFs from First Trust
Most popular First Trust ETFs on PortfoliosLab, across asset classes.
Often Compared With MDEV
What investors most often compare with MDEV, based on PortfoliosLab usage data.
Compare MDEV with Any Fund or Stock
Compare MDEV with any ETF, mutual fund, or stock using PortfoliosLab's comparison tool.