MDEV vs. CNCR

Last updated Jul 17, 2026

MDEV (First Trust Indxx Medical Devices ETF) and CNCR (Loncar Cancer Immunotherapy ETF) are both Health & Biotech Equities funds - MDEV tracks the Indxx Global Medical Equipment Index while CNCR tracks the Loncar Cancer Immunotherapy Index. Both are passively managed. MDEV charges 0.70%/yr vs 0.79%/yr for CNCR.

Performance

MDEV vs. CNCR - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in First Trust Indxx Medical Devices ETF (MDEV) and Loncar Cancer Immunotherapy ETF (CNCR). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

MDEV

• 1D: 1.70%
• 1M: 6.61%
• 6M: -7.63%
• YTD: -4.66%
• 1Y: -0.51%
• 3Y*: -1.56%
• 5Y*: -4.76%
• 10Y*: —

CNCR

• 1D: 0.00%
• 1M: 0.00%
• 6M: —
• YTD: —
• 1Y: —
• 3Y*: —
• 5Y*: —
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

MDEV vs. CNCR - Yearly Performance Comparison

	2026 (YTD)
MDEV First Trust Indxx Medical Devices ETF	-3.00%
CNCR Loncar Cancer Immunotherapy ETF	0.00%

MDEV vs. CNCR - Sectors Allocation Comparison

Sectors	MDEV	CNCR
Healthcare	100.0%	96.6%
Basic Materials	-	-
Communication Services	-	-
Consumer Cyclical	-	-
Consumer Defensive	-	-
Energy	-	-
Financial Services	-	3.3%
Industrials	-	-
Real Estate	-	-
Technology	-	-
Utilities	-	-

Return for Risk

MDEV vs. CNCR — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

MDEV

MDEV Risk / Return Rank: 9
MDEV Sharpe Ratio Rank: 9
MDEV Sortino Ratio Rank: 9
MDEV Omega Ratio Rank: 9
MDEV Calmar Ratio Rank: 9
MDEV Martin Ratio Rank: 9

CNCR

Risk / return metrics aren't available yet — we need at least 12 months of trading data to calculate them.

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

MDEV vs. CNCR - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for First Trust Indxx Medical Devices ETF (MDEV) and Loncar Cancer Immunotherapy ETF (CNCR). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.

	MDEV	CNCR	Difference
Sharpe ratio: Return per unit of total volatility	-0.03	—	—
Sortino ratio: Return per unit of downside risk	0.07	—	—
Omega ratio: Gain probability vs. loss probability	1.01	—	—
Calmar ratio: Return relative to maximum drawdown	-0.03	—	—
Martin ratio: Return relative to average drawdown	-0.06	—	—

Drawdowns

MDEV vs. CNCR - Drawdown Comparison

The maximum MDEV drawdown since its inception was -42.34%, which is greater than CNCR's maximum drawdown of 0.00%. Use the drawdown chart below to compare losses from any high point for MDEV and CNCR.

Drawdown Indicators

	MDEV	CNCR	Difference
Max Drawdown Largest peak-to-trough decline	-42.34%	0.00%	-42.34%
Max Drawdown (1Y) Largest decline over 1 year	-18.13%	—	—
Max Drawdown (3Y) Largest decline over 3 years	-22.50%	—	—
Max Drawdown (5Y) Largest decline over 5 years	-42.34%	—	—
Current Drawdown Current decline from peak	-28.65%	0.00%	-28.65%
Average Drawdown Average peak-to-trough decline	-25.76%	0.00%	-25.76%
Ulcer Index Depth and duration of drawdowns from previous peaks	8.28%	—	—

Volatility

Volatility by Period

	MDEV	CNCR	Difference
Volatility (1M) Calculated over the trailing 1-month period	5.61%	—	—
Volatility (6M) Calculated over the trailing 6-month period	12.58%	—	—
Volatility (1Y) Calculated over the trailing 1-year period	16.66%	0.00%	+16.66%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	19.09%	0.00%	+19.09%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	18.98%	0.00%	+18.98%

MDEV vs. CNCR - Expense Ratio Comparison

MDEV has a 0.70% expense ratio, which is lower than CNCR's 0.79% expense ratio.

Dividends

MDEV vs. CNCR - Dividend Comparison

MDEV's dividend yield for the trailing twelve months is around 0.11%, while CNCR has not paid dividends to shareholders.

Position	TTM
CNCR Loncar Cancer Immunotherapy ETF	0.00%
MDEV First Trust Indxx Medical Devices ETF	0.11%

Frequently Asked Questions

Which ETF is better, MDEV or CNCR?

On fees, MDEV is cheaper at 0.70% per year. The better choice depends on whether you care most about return, fees, risk, or income.

Which ETF is cheaper, MDEV or CNCR?

MDEV is cheaper with a 0.70% expense ratio, compared with 0.79% for CNCR.

Which ETF pays a higher dividend yield, MDEV or CNCR?

MDEV has the higher dividend yield at 0.11%, compared with 0.00% for CNCR.

What is the main difference between MDEV and CNCR?

MDEV tracks Indxx Global Medical Equipment Index, while CNCR tracks Loncar Cancer Immunotherapy Index. They also come from different issuers: First Trust and Exchange Traded Concepts. Their fees differ too: 0.70% for MDEV and 0.79% for CNCR.