Fidelity MSCI Health Care Index ETF (FHLC) belongs to the Health & Biotech Equities category. Below you'll find alternative ETFs from the same category, ranked by key criteria, plus funds that investors commonly compare with FHLC. Use the tables to find lower-cost options, better risk-adjusted returns, or a closer substitute for your current allocation.
Cheapest Alternatives to FHLC
FHLC charges 0.08% annually. No ETFs in the Health & Biotech Equities category have lower expense ratios; the lowest-cost alternatives shown here go as low as 0.08%.
| Symbol | Name | Expense Ratio | AUM | Inception | |
|---|---|---|---|---|---|
| State Street Health Care Select Sector SPDR ETF | 0.08% | 41.65B | Dec 1998 | FHLC vs XLV | |
| Vanguard Health Care ETF | 0.09% | 19.00B | Jan 2004 | FHLC vs VHT | |
| Portfolio Building Block World Pharma and Biotech ... | 0.13% | 951.16M | Nov 2025 | FHLC vs PBPH | |
| GSK plc ADRhedged ETF | 0.19% | 793.18K | Jan 2025 | FHLC vs GSKH | |
| Invesco Nasdaq Biotechnology ETF | 0.19% | 74.65M | Jun 2021 | FHLC vs IBBQ |
Best Risk-Adjusted Alternatives to FHLC
FHLC has a PortfoliosLab risk / return rank of 57. There are 28 ETFs in the Health & Biotech Equities category with higher risk-adjusted ranks, going as high as 96.
| Symbol | Name | Risk / Return Rank | AUM | Inception | |
|---|---|---|---|---|---|
| Virtus LifeSci Biotech Clinical Trials ETF | 96 | 57.56M | Dec 2014 | FHLC vs BBC | |
| ALPS Medical Breakthroughs ETF | 95 | 213.08M | Dec 2014 | FHLC vs SBIO | |
| SPDR S&P Biotech ETF | 94 | 11.10B | Feb 2006 | FHLC vs XBI | |
| iShares U.S. Pharmaceuticals ETF | 94 | 1.34B | May 2006 | FHLC vs IHE | |
| iShares Neuroscience and Healthcare ETF | 93 | 5.85M | Aug 2022 | FHLC vs IBRN |
Top Performing FHLC Alternatives (YTD)
FHLC is at 6.34% YTD. There are 39 ETFs in the Health & Biotech Equities category with higher YTD returns, going as high as 40.11%.
| Symbol | Name | YTD Return | AUM | Inception | |
|---|---|---|---|---|---|
| ARK Genomic Revolution Multi-Sector ETF | 40.11% | 1.31B | Oct 2014 | FHLC vs ARKG | |
| AdvisorShares Psychedelics ETF | 35.29% | 44.37M | Sep 2021 | FHLC vs PSIL | |
| Roundhill UNH WeeklyPay ETF | 34.33% | 6.01M | Dec 2025 | FHLC vs UNHW | |
| Virtus LifeSci Biotech Clinical Trials ETF | 33.14% | 57.56M | Dec 2014 | FHLC vs BBC | |
| ALPS Medical Breakthroughs ETF | 27.56% | 213.08M | Dec 2014 | FHLC vs SBIO |
Lowest Volatility Alternatives to FHLC
FHLC has 15.34% 1-year volatility. There are 8 ETFs in the Health & Biotech Equities category with lower 1-year volatility, going as low as 0.00%.
| Symbol | Name | Volatility 1Y | AUM | Inception | |
|---|---|---|---|---|---|
| Loncar Cancer Immunotherapy ETF | 0.00% | 12.73M | Oct 2015 | FHLC vs CNCR | |
| Amplify Treatments, Testing and Advancements ETF | 0.00% | 9.68M | Jun 2020 | FHLC vs GERM | |
| Horizon Kinetics SPAC Active ETF | 8.64% | 10.11M | Jun 2007 | FHLC vs SPAQ | |
| State Street Health Care Select Sector SPDR Premiu... | 10.87% | 16.78M | Jul 2025 | FHLC vs XLVI | |
| Milliman Healthcare Inflation Plus ETF | 11.73% | 982.35K | Apr 2026 | FHLC vs MHIP |
Lowest Drawdown Alternatives to FHLC
FHLC has a 1-year max drawdown of -10.38%. There are 12 ETFs in the Health & Biotech Equities category with shallower 1-year drawdowns, going as shallow as 0.00%.
| Symbol | Name | Max Drawdown 1Y | AUM | Inception | |
|---|---|---|---|---|---|
| Amplify Treatments, Testing and Advancements ETF | 0.00% | 9.68M | Jun 2020 | FHLC vs GERM | |
| Horizon Kinetics SPAC Active ETF | -4.32% | 10.11M | Jun 2007 | FHLC vs SPAQ | |
| First Trust Nasdaq Pharmaceuticals ETF | -7.47% | 36.36M | Sep 2016 | FHLC vs FTXH | |
| Invesco Nasdaq Biotechnology ETF | -8.34% | 74.65M | Jun 2021 | FHLC vs IBBQ | |
| iShares U.S. Pharmaceuticals ETF | -8.47% | 1.34B | May 2006 | FHLC vs IHE |
Other ETFs from Fidelity
The 10 most viewed Fidelity ETFs shown here include FTEC, FDVV, FBTC and span 7 categories. AUM among these funds goes as high as $27B.
| Symbol | Name | Category | Risk / Return Rank | YTD Return | AUM | Inception | |
|---|---|---|---|---|---|---|---|
| Fidelity MSCI Information Technology Index ETF | Technology Equities | 58 | 23.14% | 20.96B | Oct 2013 | FHLC vs FTEC | |
| Fidelity High Dividend ETF | Large Cap Blend Equities, Dividend | 71 | 11.08% | 9.74B | Sep 2016 | FHLC vs FDVV | |
| Fidelity Wise Origin Bitcoin Fund | Cryptocurrency | 1 | -28.99% | 10.22B | Jan 2024 | FHLC vs FBTC | |
| Fidelity Total Bond ETF | Intermediate Core-Plus Bond | 36 | 0.12% | 26.62B | Oct 2014 | FHLC vs FBND | |
| Fidelity Nasdaq Composite Index ETF | Large Cap Growth Equities | 55 | 12.20% | 10.69B | Sep 2003 | FHLC vs ONEQ | |
| Fidelity Blue Chip Growth ETF | Large Cap Growth Equities | 44 | 11.18% | 6.97B | Jun 2020 | FHLC vs FBCG | |
| Fidelity Enhanced Large Cap Core ETF | Large Cap Blend Equities | 72 | 11.33% | 7.88B | Apr 2007 | FHLC vs FELC | |
| Fidelity MSCI Utilities Index ETF | Utilities Equities | 32 | 8.15% | 2.35B | Oct 2013 | FHLC vs FUTY | |
| Fidelity Ethereum Fund | Cryptocurrency | 5 | -40.36% | 750.93M | Jul 2024 | FHLC vs FETH | |
| Fidelity Enhanced Large Cap Growth ETF | Large Cap Growth Equities | 32 | 4.30% | 5.65B | Nov 2023 | FHLC vs FELG |
Often Compared With FHLC
Investors most often compare FHLC with FSPHX, IHI, FSHCX. These 20 comparison targets span 11 categories, based on PortfoliosLab usage data.
Compare FHLC with Any Fund or Stock
Compare FHLC with any ETF, mutual fund, or stock using PortfoliosLab's comparison tool.
Pair FHLC with funds that move differently
Fidelity MSCI Health Care Index ETF alternatives help with substitution. Diversifiers are the next step when you want funds with lower historical correlation to FHLC.
Explore FHLC Diversifiers