T. Rowe Price Health Care ETF (TMED) belongs to the Health & Biotech Equities category. Below you'll find alternative ETFs from the same category, ranked by key criteria, plus funds that investors commonly compare with TMED. Use the tables to find lower-cost options, better risk-adjusted returns, or a closer substitute for your current allocation.
Cheapest Alternatives to TMED
TMED charges 0.44% annually. There are 21 ETFs in the Health & Biotech Equities category with lower expense ratios, going as low as 0.08%.
| Symbol | Name | Expense Ratio | AUM | Inception | |
|---|---|---|---|---|---|
| Fidelity MSCI Health Care Index ETF | 0.08% | 3.22B | Oct 2013 | TMED vs FHLC | |
| State Street Health Care Select Sector SPDR ETF | 0.08% | 42.10B | Dec 1998 | TMED vs XLV | |
| Vanguard Health Care ETF | 0.09% | 20.40B | Jan 2004 | TMED vs VHT | |
| VanEck Healthcare TruSector ETF | 0.10% | 850.50K | Apr 2026 | TMED vs TRUH | |
| Portfolio Building Block World Pharma and Biotech ... | 0.13% | 933.15M | Nov 2025 | TMED vs PBPH |
Best Risk-Adjusted Alternatives to TMED
TMED has a PortfoliosLab risk / return rank of 87. There are 15 ETFs in the Health & Biotech Equities category with higher risk-adjusted ranks, going as high as 96.
| Symbol | Name | Risk / Return Rank | AUM | Inception | |
|---|---|---|---|---|---|
| Virtus LifeSci Biotech Clinical Trials ETF | 96 | 47.80M | Dec 2014 | TMED vs BBC | |
| iShares U.S. Pharmaceuticals ETF | 95 | 1.65B | May 2006 | TMED vs IHE | |
| First Trust Nasdaq Pharmaceuticals ETF | 95 | 911.09M | Sep 2016 | TMED vs FTXH | |
| ALPS Medical Breakthroughs ETF | 95 | 201.57M | Dec 2014 | TMED vs SBIO | |
| Invesco Dynamic Pharmaceuticals ETF | 94 | 472.10M | Jun 2005 | TMED vs PJP |
Top Performing TMED Alternatives (YTD)
TMED is at 14.31% YTD. There are 22 ETFs in the Health & Biotech Equities category with higher YTD returns, going as high as 36.76%.
| Symbol | Name | YTD Return | AUM | Inception | |
|---|---|---|---|---|---|
| ARK Genomic Revolution Multi-Sector ETF | 36.76% | 1.73B | Oct 2014 | TMED vs ARKG | |
| AdvisorShares Psychedelics ETF | 36.69% | 48.53M | Sep 2021 | TMED vs PSIL | |
| Roundhill UNH WeeklyPay ETF | 28.89% | 7.27M | Dec 2025 | TMED vs UNHW | |
| Virtus LifeSci Biotech Clinical Trials ETF | 27.03% | 47.80M | Dec 2014 | TMED vs BBC | |
| SPDR S&P Health Care Services ETF | 25.67% | 206.72M | Sep 2011 | TMED vs XHS |
Lowest Volatility Alternatives to TMED
TMED has 18.29% 1-year volatility. There are 26 ETFs in the Health & Biotech Equities category with lower 1-year volatility, going as low as 0.00%.
| Symbol | Name | Volatility 1Y | AUM | Inception | |
|---|---|---|---|---|---|
| Loncar Cancer Immunotherapy ETF | 0.00% | 12.73M | Oct 2015 | TMED vs CNCR | |
| Amplify Treatments, Testing and Advancements ETF | 0.00% | 9.68M | Jun 2020 | TMED vs GERM | |
| Horizon Kinetics SPAC Active ETF | 8.66% | 10.09M | Jun 2007 | TMED vs SPAQ | |
| State Street Health Care Select Sector SPDR Premiu... | 10.75% | 21.55M | Jul 2025 | TMED vs XLVI | |
| Milliman Healthcare Inflation Plus ETF | 10.92% | 982.35K | Apr 2026 | TMED vs MHIP |
Lowest Drawdown Alternatives to TMED
TMED has a 1-year max drawdown of -11.11%. There are 24 ETFs in the Health & Biotech Equities category with shallower 1-year drawdowns, going as shallow as 0.00%.
| Symbol | Name | Max Drawdown 1Y | AUM | Inception | |
|---|---|---|---|---|---|
| Amplify Treatments, Testing and Advancements ETF | 0.00% | 9.68M | Jun 2020 | TMED vs GERM | |
| Horizon Kinetics SPAC Active ETF | -4.20% | 10.09M | Jun 2007 | TMED vs SPAQ | |
| First Trust Nasdaq Pharmaceuticals ETF | -7.47% | 911.09M | Sep 2016 | TMED vs FTXH | |
| State Street Health Care Select Sector SPDR Premiu... | -8.14% | 21.55M | Jul 2025 | TMED vs XLVI | |
| Invesco Nasdaq Biotechnology ETF | -8.34% | 75.06M | Jun 2021 | TMED vs IBBQ |
Other ETFs from T. Rowe Price
The 10 most viewed T. Rowe Price ETFs shown here include TCAF, TFLR, TDVG and span 8 categories. AUM among these funds goes as high as $8B.
| Symbol | Name | Category | Risk / Return Rank | YTD Return | AUM | Inception | |
|---|---|---|---|---|---|---|---|
| T. Rowe Price Capital Appreciation Equity ETF | Large Cap Blend Equities | 55 | 10.23% | 8.03B | Jun 2023 | TMED vs TCAF | |
| T. Rowe Price Floating Rate ETF | Bank Loan | 84 | 1.94% | 675.28M | Nov 2022 | TMED vs TFLR | |
| T. Rowe Price Dividend Growth ETF | Large Cap Blend Equities, Dividend, Actively Managed | 82 | 11.24% | 1.42B | Aug 2020 | TMED vs TDVG | |
| T. Rowe Price Ultra Short-Term Bond ETF | Ultrashort Bond | 99 | 2.34% | 1.30B | Sep 2021 | TMED vs TBUX | |
| T. Rowe Price Blue Chip Growth ETF | Large Cap Growth Equities | 22 | 0.24% | 2.10B | Aug 2020 | TMED vs TCHP | |
| T. Rowe Price US Equity Research ETF | Large Cap Blend Equities | 73 | 11.76% | 4.26B | Jun 2021 | TMED vs TSPA | |
| T. Rowe Price Growth Stock ETF | Large Cap Growth Equities | 23 | 1.59% | 983.73M | Aug 2020 | TMED vs TGRW | |
| T. Rowe Price U.S. High Yield ETF | High Yield Bonds | 63 | 2.03% | 841.12M | Oct 2022 | TMED vs THYF | |
| T. Rowe Price International Equity ETF | Foreign Large Cap Equities | 63 | 13.28% | 1.58B | Jun 2023 | TMED vs TOUS | |
| T. Rowe Price Growth ETF | Large Cap Growth Equities | 27 | 3.43% | 1.49B | Jun 2023 | TMED vs TGRT |
Often Compared With TMED
Investors most often compare TMED with CANC, GSKH, BBH. These 20 comparison targets span 9 categories, based on PortfoliosLab usage data.
Compare TMED with Any Fund or Stock
Compare TMED with any ETF, mutual fund, or stock using PortfoliosLab's comparison tool.
Pair TMED with funds that move differently
T. Rowe Price Health Care ETF alternatives help with substitution. Diversifiers are the next step when you want funds with lower historical correlation to TMED.
Explore TMED Diversifiers