TMED vs. SBIO

Last updated Jun 3, 2026

TMED (T. Rowe Price Health Care ETF) and SBIO (ALPS Medical Breakthroughs ETF) are both Health & Biotech Equities funds. A 0.71 correlation means they provide meaningful diversification when combined. TMED charges 0.44%/yr vs 0.50%/yr for SBIO.

Performance

TMED vs. SBIO - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in T. Rowe Price Health Care ETF (TMED) and ALPS Medical Breakthroughs ETF (SBIO). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, TMED achieves a 2.81% return, which is significantly higher than SBIO's -1.78% return.

TMED

• 1D: -2.33%
• 1M: 1.95%
• YTD: 2.81%
• 6M: 4.16%
• 1Y: —
• 3Y*: —
• 5Y*: —
• 10Y*: —

SBIO

• 1D: -4.73%
• 1M: -6.02%
• YTD: -1.78%
• 6M: 5.47%
• 1Y: 67.29%
• 3Y*: 17.25%
• 5Y*: 2.56%
• 10Y*: 7.86%

*Multi-year figures are annualized to reflect compound growth (CAGR)

TMED vs. SBIO - Yearly Performance Comparison

	2026 (YTD)	2025
TMED T. Rowe Price Health Care ETF	2.81%	18.92%
SBIO ALPS Medical Breakthroughs ETF	-1.78%	63.73%

Correlation

The correlation between TMED and SBIO is 0.71, which is moderate. They share some common price drivers but move independently often enough to provide real diversification benefit when combined.

	Correlation
Correlation (All Time) Calculated using the full available price history since Jun 13, 2025	0.71

Return for Risk

TMED vs. SBIO — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

SBIO

SBIO Risk / Return Rank: 74
SBIO Sharpe Ratio Rank: 69
SBIO Sortino Ratio Rank: 68
SBIO Omega Ratio Rank: 60
SBIO Calmar Ratio Rank: 90
SBIO Martin Ratio Rank: 84

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

TMED vs. SBIO - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for T. Rowe Price Health Care ETF (TMED) and ALPS Medical Breakthroughs ETF (SBIO). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Risk / return metrics aren't available yet — we need at least 12 months of trading data to calculate them.

Sharpe Ratios by Period

	TMED	SBIO	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	—	2.30	—
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	—	0.08	—
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	—	0.24	—
Sharpe Ratio (All Time) Calculated using the full available price history	1.29	0.21	+1.08

Drawdowns

TMED vs. SBIO - Drawdown Comparison

The maximum TMED drawdown since its inception was -11.11%, smaller than the maximum SBIO drawdown of -63.06%. Use the drawdown chart below to compare losses from any high point for TMED and SBIO.

Drawdown Indicators

	TMED	SBIO	Difference
Max Drawdown Largest peak-to-trough decline	-11.11%	-63.06%	+51.95%
Max Drawdown (1Y) Largest decline over 1 year	—	-12.66%	—
Max Drawdown (3Y) Largest decline over 3 years	—	-42.44%	—
Max Drawdown (5Y) Largest decline over 5 years	—	-53.10%	—
Max Drawdown (10Y) Largest decline over 10 years	—	-63.06%	—
Current Drawdown Current decline from peak	-3.75%	-17.95%	+14.20%
Average Drawdown Average peak-to-trough decline	-2.59%	-28.45%	+25.86%
Ulcer Index Depth and duration of drawdowns from previous peaks	—	4.15%	—

Volatility

Volatility by Period

	TMED	SBIO	Difference
Volatility (1M) Calculated over the trailing 1-month period	—	9.94%	—
Volatility (6M) Calculated over the trailing 6-month period	—	22.86%	—
Volatility (1Y) Calculated over the trailing 1-year period	18.05%	29.55%	-11.50%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	18.05%	33.55%	-15.50%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	18.05%	33.18%	-15.13%

TMED vs. SBIO - Expense Ratio Comparison

TMED has a 0.44% expense ratio, which is lower than SBIO's 0.50% expense ratio.

Dividends

TMED vs. SBIO - Dividend Comparison

TMED's dividend yield for the trailing twelve months is around 0.53%, while SBIO has not paid dividends to shareholders.

Position	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017
SBIO ALPS Medical Breakthroughs ETF	0.00%	0.00%	3.55%	0.22%	0.00%	0.00%	0.00%	0.04%	2.79%	1.77%
TMED T. Rowe Price Health Care ETF	0.53%	0.54%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%

Frequently Asked Questions

Can I hold both TMED and SBIO in my portfolio?

TMED and SBIO have a correlation of 0.71, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which ETF is better, TMED or SBIO?

On fees, TMED is cheaper at 0.44% per year. The better choice depends on whether you care most about return, fees, risk, or income.

Which ETF is cheaper, TMED or SBIO?

TMED is cheaper with a 0.44% expense ratio, compared with 0.50% for SBIO.

Which ETF pays a higher dividend yield, TMED or SBIO?

TMED has the higher dividend yield at 0.53%, compared with 0.00% for SBIO.

What is the main difference between TMED and SBIO?

They also come from different issuers: T. Rowe Price and SS&C. Their fees differ too: 0.44% for TMED and 0.50% for SBIO.