AdvisorShares Psychedelics ETF (PSIL) belongs to the Health & Biotech Equities category. Below you'll find alternative ETFs from the same category, ranked by key criteria, plus funds that investors commonly compare with PSIL. Use the tables to find lower-cost options, better risk-adjusted returns, or a closer substitute for your current allocation.
Cheapest Alternatives to PSIL
PSIL charges 1.00% annually. There are 64 ETFs in the Health & Biotech Equities category with lower expense ratios, going as low as 0.08%.
| Symbol | Name | Expense Ratio | AUM | Inception | |
|---|---|---|---|---|---|
| Fidelity MSCI Health Care Index ETF | 0.08% | 3.22B | Oct 2013 | PSIL vs FHLC | |
| State Street Health Care Select Sector SPDR ETF | 0.08% | 41.65B | Dec 1998 | PSIL vs XLV | |
| Vanguard Health Care ETF | 0.09% | 19.00B | Jan 2004 | PSIL vs VHT | |
| Portfolio Building Block World Pharma and Biotech ... | 0.13% | 951.16M | Nov 2025 | PSIL vs PBPH | |
| GSK plc ADRhedged ETF | 0.19% | 793.18K | Jan 2025 | PSIL vs GSKH |
Best Risk-Adjusted Alternatives to PSIL
PSIL has a PortfoliosLab risk / return rank of 66. There are 21 ETFs in the Health & Biotech Equities category with higher risk-adjusted ranks, going as high as 96.
| Symbol | Name | Risk / Return Rank | AUM | Inception | |
|---|---|---|---|---|---|
| Virtus LifeSci Biotech Clinical Trials ETF | 96 | 57.56M | Dec 2014 | PSIL vs BBC | |
| ALPS Medical Breakthroughs ETF | 95 | 213.08M | Dec 2014 | PSIL vs SBIO | |
| SPDR S&P Biotech ETF | 94 | 11.10B | Feb 2006 | PSIL vs XBI | |
| iShares U.S. Pharmaceuticals ETF | 93 | 1.34B | May 2006 | PSIL vs IHE | |
| iShares Neuroscience and Healthcare ETF | 93 | 5.85M | Aug 2022 | PSIL vs IBRN |
Top Performing PSIL Alternatives (YTD)
PSIL is at 38.09% YTD. There is 1 ETF in the Health & Biotech Equities category with a higher YTD return, going as high as 42.63%.
| Symbol | Name | YTD Return | AUM | Inception | |
|---|---|---|---|---|---|
| ARK Genomic Revolution Multi-Sector ETF | 42.63% | 1.31B | Oct 2014 | PSIL vs ARKG | |
| Virtus LifeSci Biotech Clinical Trials ETF | 37.88% | 57.56M | Dec 2014 | PSIL vs BBC | |
| Roundhill UNH WeeklyPay ETF | 32.77% | 6.01M | Dec 2025 | PSIL vs UNHW | |
| ALPS Medical Breakthroughs ETF | 31.24% | 213.08M | Dec 2014 | PSIL vs SBIO | |
| SPDR S&P Biotech ETF | 30.56% | 11.10B | Feb 2006 | PSIL vs XBI |
Lowest Volatility Alternatives to PSIL
PSIL has 41.28% 1-year volatility. There are 62 ETFs in the Health & Biotech Equities category with lower 1-year volatility, going as low as 0.00%.
| Symbol | Name | Volatility 1Y | AUM | Inception | |
|---|---|---|---|---|---|
| Loncar Cancer Immunotherapy ETF | 0.00% | 12.73M | Oct 2015 | PSIL vs CNCR | |
| Amplify Treatments, Testing and Advancements ETF | 0.00% | 9.68M | Jun 2020 | PSIL vs GERM | |
| Horizon Kinetics SPAC Active ETF | 8.63% | 10.11M | Jun 2007 | PSIL vs SPAQ | |
| State Street Health Care Select Sector SPDR Premiu... | 10.89% | 16.78M | Jul 2025 | PSIL vs XLVI | |
| Milliman Healthcare Inflation Plus ETF | 11.77% | 982.35K | Apr 2026 | PSIL vs MHIP |
Lowest Drawdown Alternatives to PSIL
PSIL has a 1-year max drawdown of -20.38%. There are 51 ETFs in the Health & Biotech Equities category with shallower 1-year drawdowns, going as shallow as 0.00%.
| Symbol | Name | Max Drawdown 1Y | AUM | Inception | |
|---|---|---|---|---|---|
| Amplify Treatments, Testing and Advancements ETF | 0.00% | 9.68M | Jun 2020 | PSIL vs GERM | |
| Horizon Kinetics SPAC Active ETF | -4.32% | 10.11M | Jun 2007 | PSIL vs SPAQ | |
| First Trust Nasdaq Pharmaceuticals ETF | -7.47% | 36.36M | Sep 2016 | PSIL vs FTXH | |
| Invesco Nasdaq Biotechnology ETF | -8.34% | 74.65M | Jun 2021 | PSIL vs IBBQ | |
| iShares U.S. Pharmaceuticals ETF | -8.47% | 1.34B | May 2006 | PSIL vs IHE |
Other ETFs from AdvisorShares
The 10 most viewed AdvisorShares ETFs shown here include MSOS, AADR, YOLO and span 7 categories. AUM among these funds goes as high as $915M.
| Symbol | Name | Category | Risk / Return Rank | YTD Return | AUM | Inception | |
|---|---|---|---|---|---|---|---|
| AdvisorShares Pure US Cannabis ETF | Small Cap Blend Equities, Cannabis | 27 | -4.87% | 915.20M | Sep 2020 | PSIL vs MSOS | |
| AdvisorShares Dorsey Wright ADR ETF | Global Equities | 16 | -1.82% | 42.05M | Jul 2010 | PSIL vs AADR | |
| AdvisorShares Pure Cannabis ETF | Cannabis | 19 | -17.44% | 31.74M | Apr 2019 | PSIL vs YOLO | |
| AdvisorShares Focused Equity ETF | Large Cap Growth Equities | 7 | -0.84% | 129.89M | Sep 2016 | PSIL vs CWS | |
| AdvisorShares Ranger Equity Bear ETF | Inverse Equities | 11 | 0.06% | 64.16M | Jan 2011 | PSIL vs HDGE | |
| Advisorshares Msos 2x Daily ETF | Leveraged Equities | 16 | -42.41% | 55.09M | Aug 2022 | PSIL vs MSOX | |
| AdvisorShares Gerber Kawasaki ETF | Large Cap Growth Equities | 38 | 13.26% | 31.47M | Jul 2021 | PSIL vs GK | |
| AdvisorShares Q Dynamic Growth ETF | Large Cap Growth Equities | 57 | 9.47% | 33.16M | Dec 2020 | PSIL vs QPX | |
| AdvisorShares Vice ETF | Consumer Discretionary Equities | 7 | 5.76% | 7.39M | Dec 2017 | PSIL vs VICE | |
| AdvisorShares Hotel ETF | Consumer Discretionary Equities | 18 | 8.61% | 2.90M | Apr 2021 | PSIL vs BEDZ |
Often Compared With PSIL
Investors most often compare PSIL with XHE, IBB, PINK. These 20 comparison targets span 1 categories, based on PortfoliosLab usage data.
Compare PSIL with Any Fund or Stock
Compare PSIL with any ETF, mutual fund, or stock using PortfoliosLab's comparison tool.
Pair PSIL with funds that move differently
AdvisorShares Psychedelics ETF alternatives help with substitution. Diversifiers are the next step when you want funds with lower historical correlation to PSIL.
Explore PSIL Diversifiers