PSIL vs. FMED

Last updated Jun 23, 2026

PSIL (AdvisorShares Psychedelics ETF) and FMED (Fidelity Disruptive Medicine ETF) are both Health & Biotech Equities funds. Both are actively managed. Over the past 3 years, PSIL returned 10.23%/yr vs 1.62%/yr for FMED. At a 0.46 correlation, their price movements are largely independent. PSIL charges 1.00%/yr vs 0.50%/yr for FMED.

Performance

PSIL vs. FMED - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in AdvisorShares Psychedelics ETF (PSIL) and Fidelity Disruptive Medicine ETF (FMED). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, PSIL achieves a 24.34% return, which is significantly higher than FMED's -3.44% return.

PSIL

• 1D: 6.27%
• 1M: 1.04%
• YTD: 24.34%
• 6M: 22.35%
• 1Y: 54.09%
• 3Y*: 10.23%
• 5Y*: —
• 10Y*: —

FMED

• 1D: 0.07%
• 1M: 5.53%
• YTD: -3.44%
• 6M: -5.57%
• 1Y: 12.20%
• 3Y*: 1.62%
• 5Y*: —
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

PSIL vs. FMED - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023
PSIL AdvisorShares Psychedelics ETF	24.34%	74.55%	-19.50%	-22.62%
FMED Fidelity Disruptive Medicine ETF	-3.44%	9.69%	2.29%	-3.59%

Correlation

The correlation between PSIL and FMED is 0.56, which is moderate. They share some common price drivers but move independently often enough to provide real diversification benefit when combined.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.56
Correlation (3Y) Calculated over the trailing 3-year period	0.46
Correlation (All Time) Calculated using the full available price history since Jun 12, 2023	0.46

The correlation between PSIL and FMED has been stable across timeframes, ranging from 0.46 to 0.56 - a consistent structural relationship.

PSIL vs. FMED - Sectors Allocation Comparison

Sectors	PSIL	FMED
Healthcare	100.0%	97.6%
Basic Materials	-	-
Communication Services	-	-
Consumer Cyclical	-	-
Consumer Defensive	-	-
Energy	-	-
Financial Services	-	-
Industrials	-	-
Real Estate	-	-
Technology	-	0.9%
Utilities	-	-

Return for Risk

PSIL vs. FMED — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

PSIL

PSIL Risk / Return Rank: 40
PSIL Sharpe Ratio Rank: 37
PSIL Sortino Ratio Rank: 36
PSIL Omega Ratio Rank: 36
PSIL Calmar Ratio Rank: 56
PSIL Martin Ratio Rank: 37

FMED

FMED Risk / Return Rank: 18
FMED Sharpe Ratio Rank: 19
FMED Sortino Ratio Rank: 20
FMED Omega Ratio Rank: 18
FMED Calmar Ratio Rank: 17
FMED Martin Ratio Rank: 15

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

PSIL vs. FMED - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for AdvisorShares Psychedelics ETF (PSIL) and Fidelity Disruptive Medicine ETF (FMED). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.

	PSIL	FMED	Difference
Sharpe ratio: Return per unit of total volatility	1.28	0.64	+0.64
Sortino ratio: Return per unit of downside risk	1.83	1.06	+0.76
Omega ratio: Gain probability vs. loss probability	1.23	1.12	+0.11
Calmar ratio: Return relative to maximum drawdown	2.67	0.67	+2.00
Martin ratio: Return relative to average drawdown	5.56	1.46	+4.10

PSIL vs. FMED - Sharpe Ratio Comparison

The current PSIL Sharpe Ratio is 1.28, which is higher than the FMED Sharpe Ratio of 0.64. The chart below compares the historical Sharpe Ratios of PSIL and FMED, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Drawdowns

PSIL vs. FMED - Drawdown Comparison

The maximum PSIL drawdown since its inception was -92.72%, which is greater than FMED's maximum drawdown of -21.84%. Use the drawdown chart below to compare losses from any high point for PSIL and FMED.

Drawdown Indicators

	PSIL	FMED	Difference
Max Drawdown Largest peak-to-trough decline	-92.72%	-21.84%	-70.88%
Max Drawdown (1Y) Largest decline over 1 year	-20.38%	-18.33%	-2.05%
Max Drawdown (3Y) Largest decline over 3 years	-64.62%	-21.84%	-42.78%
Current Drawdown Current decline from peak	-75.81%	-9.41%	-66.40%
Average Drawdown Average peak-to-trough decline	-76.71%	-7.10%	-69.61%
Ulcer Index Depth and duration of drawdowns from previous peaks	9.86%	8.36%	+1.50%

Volatility

PSIL vs. FMED - Volatility Comparison

AdvisorShares Psychedelics ETF (PSIL) has a higher volatility of 13.08% compared to Fidelity Disruptive Medicine ETF (FMED) at 6.55%. This indicates that PSIL's price experiences larger fluctuations and is considered to be riskier than FMED based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	PSIL	FMED	Difference
Volatility (1M) Calculated over the trailing 1-month period	13.08%	6.55%	+6.53%
Volatility (6M) Calculated over the trailing 6-month period	28.55%	15.01%	+13.54%
Volatility (1Y) Calculated over the trailing 1-year period	42.51%	19.29%	+23.22%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	63.01%	18.54%	+44.47%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	63.01%	18.54%	+44.47%

PSIL vs. FMED - Expense Ratio Comparison

PSIL has a 1.00% expense ratio, which is higher than FMED's 0.50% expense ratio.

Dividends

PSIL vs. FMED - Dividend Comparison

PSIL's dividend yield for the trailing twelve months is around 8.04%, while FMED has not paid dividends to shareholders.

Position	TTM	2025	2024	2023	2022
FMED Fidelity Disruptive Medicine ETF	0.00%	0.00%	0.46%	0.00%	0.00%
PSIL AdvisorShares Psychedelics ETF	8.04%	10.95%	1.49%	0.24%	2.91%

Frequently Asked Questions

Can I hold both PSIL and FMED in my portfolio?

PSIL and FMED have a correlation of 0.56, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, PSIL or FMED?

PSIL has higher volatility (13.08%) compared to FMED (6.55%). In terms of maximum drawdown, PSIL dropped -92.72% vs FMED's -21.84%.

Which ETF is better, PSIL or FMED?

On 3-year performance, PSIL leads with 10.23% vs 1.62% for FMED. On fees, FMED is cheaper at 0.50% per year. On volatility, FMED has been the lower-risk option at 6.55%. The better choice depends on whether you care most about return, fees, risk, or income.

Which ETF has performed better, PSIL or FMED?

Over the 3-year period, PSIL has performed better with a 10.23% return vs 1.62%. Past performance does not guarantee future results, so compare this with risk, fees, and fund exposure.

Which ETF is cheaper, PSIL or FMED?

FMED is cheaper with a 0.50% expense ratio, compared with 1.00% for PSIL.

Which ETF pays a higher dividend yield, PSIL or FMED?

PSIL has the higher dividend yield at 8.04%, compared with 0.00% for FMED.

What is the main difference between PSIL and FMED?

They also come from different issuers: AdvisorShares and Fidelity. Their fees differ too: 1.00% for PSIL and 0.50% for FMED.

Which has better risk-adjusted returns?

PSIL currently has the higher Sharpe Ratio (1.28 vs 0.64), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.