PSIL vs. SBIO
PSIL (AdvisorShares Psychedelics ETF) and SBIO (ALPS Medical Breakthroughs ETF) are both Health & Biotech Equities funds. PSIL is actively managed, while SBIO is passively managed. Over the past 3 years, PSIL returned 11.93%/yr vs 27.24%/yr for SBIO. Their 0.50 correlation means they have sometimes moved together and sometimes differently. PSIL charges 1.00%/yr vs 0.50%/yr for SBIO.
Performance
PSIL vs. SBIO - Performance Comparison
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Returns By Period
In the year-to-date period, PSIL achieves a 36.87% return, which is significantly higher than SBIO's 23.71% return.
PSIL
- 1D
- -1.14%
- 1M
- 1.16%
- 6M
- 40.80%
- YTD
- 36.87%
- 1Y
- 60.42%
- 3Y*
- 11.93%
- 5Y*
- —
- 10Y*
- —
- ALL TIME*
- -23.56%
SBIO
- 1D
- -2.82%
- 1M
- -2.37%
- 6M
- 23.63%
- YTD
- 23.71%
- 1Y
- 93.80%
- 3Y*
- 27.24%
- 5Y*
- 8.36%
- 10Y*
- 10.60%
- ALL TIME*
- 9.13%
Liquidity Comparison
| Position | Avg. Volume Value (2W) | Avg. Volume Value (1M) | Avg. Volume Value (3M) |
|---|---|---|---|
| $992.95K | $1.18M | $917.29K | |
| $1.96M | $3.19M | $2.15M |
PSIL vs. SBIO - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | |
|---|---|---|---|---|---|---|
PSIL AdvisorShares Psychedelics ETF | 36.87% | 74.55% | -19.50% | -25.12% | -67.24% | -42.72% |
SBIO ALPS Medical Breakthroughs ETF | 23.71% | 55.07% | 3.81% | 8.68% | -28.08% | -8.86% |
Correlation
The correlation between PSIL and SBIO is 0.61, which is moderate. They have sometimes moved together and sometimes differently, sharing some price drivers without tracking each other closely.
| Correlation | |
|---|---|
Correlation (1Y) Focuses on recent behavior, but can change the most. | 0.61 |
Correlation (3Y) Balances recent behavior with more history. | 0.50 |
Correlation (All Time) Calculated using the full available price history since Sep 16, 2021 | 0.50 |
The correlation between PSIL and SBIO shifts across timeframes, from 0.49 (3 years) to 0.61 (1 year), reflecting how their relationship changes across market environments.
PSIL vs. SBIO - Sectors Allocation Comparison
Sectors
PSIL
SBIO
Healthcare
Basic Materials
-
-
Communication Services
-
-
Consumer Cyclical
-
-
Consumer Defensive
-
-
Energy
-
-
Financial Services
-
Industrials
-
-
Real Estate
-
-
Technology
-
-
Utilities
-
-
Healthcare
PSIL
SBIO
Basic Materials
PSIL
-
SBIO
-
Communication Services
PSIL
-
SBIO
-
Consumer Cyclical
PSIL
-
SBIO
-
Consumer Defensive
PSIL
-
SBIO
-
Energy
PSIL
-
SBIO
-
Financial Services
PSIL
-
SBIO
Industrials
PSIL
-
SBIO
-
Real Estate
PSIL
-
SBIO
-
Technology
PSIL
-
SBIO
-
Utilities
PSIL
-
SBIO
-
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Return for Risk
PSIL vs. SBIO — Risk / Return Rank
PSIL
SBIO
PSIL vs. SBIO - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for AdvisorShares Psychedelics ETF (PSIL) and ALPS Medical Breakthroughs ETF (SBIO). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| PSIL | SBIO | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | -1.70 | ||
| Sortino ratioReturn per unit of downside risk | -1.88 | ||
| Omega ratioGain probability vs. loss probability | 1.23 | 1.45 | -0.22 |
| Calmar ratioReturn relative to maximum drawdown | 2.69 | 7.47 | -4.78 |
| Martin ratioReturn relative to average drawdown | 5.59 | 19.68 | -14.09 |
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Drawdowns
PSIL vs. SBIO - Drawdown Comparison
The maximum PSIL drawdown since its inception was -92.72%, which is greater than SBIO's maximum drawdown of -63.06%. Use the drawdown chart below to compare losses from any high point for PSIL and SBIO.
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Drawdown Indicators
| PSIL | SBIO | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -92.72% | -63.06% | -29.66% |
Max Drawdown (1Y)Largest decline over 1 year | -20.38% | -12.66% | -7.72% |
Max Drawdown (3Y)Largest decline over 3 years | -61.25% | -42.44% | -18.81% |
Max Drawdown (5Y)Largest decline over 5 years | — | -52.49% | — |
Max Drawdown (10Y)Largest decline over 10 years | — | -63.06% | — |
Current DrawdownCurrent decline from peak | -73.38% | -8.09% | -65.29% |
Average DrawdownAverage peak-to-trough decline | -76.64% | -28.14% | -48.50% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 9.78% | 4.80% | +4.98% |
Volatility
PSIL vs. SBIO - Volatility Comparison
The current volatility for AdvisorShares Psychedelics ETF (PSIL) is 8.09%, while ALPS Medical Breakthroughs ETF (SBIO) has a volatility of 10.05%. This indicates that PSIL experiences smaller price fluctuations and is considered to be less risky than SBIO based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| PSIL | SBIO | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 8.09% | 10.05% | -1.96% |
Volatility (6M)Calculated over the trailing 6-month period | 29.57% | 24.16% | +5.41% |
Volatility (1Y)Calculated over the trailing 1-year period | 40.73% | 31.04% | +9.69% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 62.54% | 33.86% | +28.68% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 62.54% | 33.18% | +29.36% |
PSIL vs. SBIO - Expense Ratio Comparison
PSIL has a 1.00% expense ratio, which is higher than SBIO's 0.50% expense ratio.
Dividends
PSIL vs. SBIO - Dividend Comparison
PSIL's dividend yield for the trailing twelve months is around 7.25%, while SBIO has not paid dividends to shareholders.
| Position | TTM | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 |
|---|---|---|---|---|---|---|---|---|---|---|
PSIL AdvisorShares Psychedelics ETF | 7.25% | 10.95% | 1.49% | 0.24% | 2.91% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% |
SBIO ALPS Medical Breakthroughs ETF | 0.00% | 0.00% | 3.55% | 0.22% | 0.00% | 0.00% | 0.00% | 0.04% | 2.79% | 1.77% |
Frequently Asked Questions
PSIL and SBIO have a correlation of 0.61, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
SBIO has higher volatility (10.05%) compared to PSIL (8.09%). In terms of maximum drawdown, PSIL dropped -92.72% vs SBIO's -63.06%.
On 3-year performance, SBIO leads with 27.24% vs 11.93% for PSIL. On fees, SBIO is cheaper at 0.50% per year. On volatility, PSIL has been the lower-risk option at 8.09%. The better choice depends on whether you care most about return, fees, risk, or income.
Over the 3-year period, SBIO has performed better with a 27.24% return vs 11.93%. Past performance does not guarantee future results, so compare this with risk, fees, and fund exposure.
SBIO is cheaper with a 0.50% expense ratio, compared with 1.00% for PSIL.
PSIL has the higher dividend yield at 7.25%, compared with 0.00% for SBIO.
They also come from different issuers: AdvisorShares and SS&C. Their fees differ too: 1.00% for PSIL and 0.50% for SBIO.
SBIO currently has the higher Sharpe Ratio (3.05 vs 1.35), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
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