Simplify Health Care ETF (PINK) belongs to the Health & Biotech Equities category. Below you'll find alternative ETFs from the same category, ranked by key criteria, plus funds that investors commonly compare with PINK. Use the tables to find lower-cost options, better risk-adjusted returns, or a closer substitute for your current allocation.
Cheapest Alternatives to PINK
PINK charges 0.50% annually. There are 25 ETFs in the Health & Biotech Equities category with lower expense ratios, going as low as 0.08%.
| Symbol | Name | Expense Ratio | AUM | Inception | |
|---|---|---|---|---|---|
| State Street Health Care Select Sector SPDR ETF | 0.08% | 41.65B | Dec 1998 | PINK vs XLV | |
| Fidelity MSCI Health Care Index ETF | 0.08% | 3.22B | Oct 2013 | PINK vs FHLC | |
| Vanguard Health Care ETF | 0.09% | 19.00B | Jan 2004 | PINK vs VHT | |
| Portfolio Building Block World Pharma and Biotech ... | 0.13% | 951.16M | Nov 2025 | PINK vs PBPH | |
| GSK plc ADRhedged ETF | 0.19% | 793.18K | Jan 2025 | PINK vs GSKH |
Best Risk-Adjusted Alternatives to PINK
PINK has a PortfoliosLab risk / return rank of 54. There are 32 ETFs in the Health & Biotech Equities category with higher risk-adjusted ranks, going as high as 96.
| Symbol | Name | Risk / Return Rank | AUM | Inception | |
|---|---|---|---|---|---|
| Virtus LifeSci Biotech Clinical Trials ETF | 96 | 57.56M | Dec 2014 | PINK vs BBC | |
| ALPS Medical Breakthroughs ETF | 94 | 213.08M | Dec 2014 | PINK vs SBIO | |
| First Trust Nasdaq Pharmaceuticals ETF | 94 | 36.36M | Sep 2016 | PINK vs FTXH | |
| iShares U.S. Pharmaceuticals ETF | 93 | 1.34B | May 2006 | PINK vs IHE | |
| SPDR S&P Biotech ETF | 93 | 11.10B | Feb 2006 | PINK vs XBI |
Top Performing PINK Alternatives (YTD)
PINK is at 6.69% YTD. There are 36 ETFs in the Health & Biotech Equities category with higher YTD returns, going as high as 41.35%.
| Symbol | Name | YTD Return | AUM | Inception | |
|---|---|---|---|---|---|
| AdvisorShares Psychedelics ETF | 41.35% | 44.37M | Sep 2021 | PINK vs PSIL | |
| ARK Genomic Revolution Multi-Sector ETF | 38.38% | 1.31B | Oct 2014 | PINK vs ARKG | |
| Roundhill UNH WeeklyPay ETF | 31.46% | 6.01M | Dec 2025 | PINK vs UNHW | |
| Virtus LifeSci Biotech Clinical Trials ETF | 29.44% | 57.56M | Dec 2014 | PINK vs BBC | |
| SPDR S&P Health Care Services ETF | 26.76% | 204.10M | Sep 2011 | PINK vs XHS |
Lowest Volatility Alternatives to PINK
PINK has 18.46% 1-year volatility. There are 27 ETFs in the Health & Biotech Equities category with lower 1-year volatility, going as low as 0.00%.
| Symbol | Name | Volatility 1Y | AUM | Inception | |
|---|---|---|---|---|---|
| Loncar Cancer Immunotherapy ETF | 0.00% | 12.73M | Oct 2015 | PINK vs CNCR | |
| Amplify Treatments, Testing and Advancements ETF | 0.00% | 9.68M | Jun 2020 | PINK vs GERM | |
| Horizon Kinetics SPAC Active ETF | 8.62% | 10.11M | Jun 2007 | PINK vs SPAQ | |
| State Street Health Care Select Sector SPDR Premiu... | 11.06% | 16.78M | Jul 2025 | PINK vs XLVI | |
| Milliman Healthcare Inflation Plus ETF | 11.54% | 982.35K | Apr 2026 | PINK vs MHIP |
Lowest Drawdown Alternatives to PINK
PINK has a 1-year max drawdown of -16.81%. There are 42 ETFs in the Health & Biotech Equities category with shallower 1-year drawdowns, going as shallow as 0.00%.
| Symbol | Name | Max Drawdown 1Y | AUM | Inception | |
|---|---|---|---|---|---|
| Amplify Treatments, Testing and Advancements ETF | 0.00% | 9.68M | Jun 2020 | PINK vs GERM | |
| Horizon Kinetics SPAC Active ETF | -4.32% | 10.11M | Jun 2007 | PINK vs SPAQ | |
| First Trust Nasdaq Pharmaceuticals ETF | -7.47% | 36.36M | Sep 2016 | PINK vs FTXH | |
| Invesco Nasdaq Biotechnology ETF | -8.34% | 74.65M | Jun 2021 | PINK vs IBBQ | |
| iShares U.S. Pharmaceuticals ETF | -8.47% | 1.34B | May 2006 | PINK vs IHE |
Other ETFs from Simplify
The 10 most viewed Simplify ETFs shown here include SVOL, CTA, HEQT and span 14 categories. AUM among these funds goes as high as $2B.
| Symbol | Name | Category | Risk / Return Rank | YTD Return | AUM | Inception | |
|---|---|---|---|---|---|---|---|
| Simplify Volatility Premium ETF | Volatility | 33 | 2.18% | 538.77M | May 2021 | PINK vs SVOL | |
| Simplify Managed Futures Strategy ETF | Systematic Trend | 10 | 0.06% | 1.51B | Mar 2022 | PINK vs CTA | |
| Simplify Hedged Equity ETF | Equity Hedged, Options Trading, Actively Managed | 74 | 5.75% | 300.35M | Nov 2021 | PINK vs HEQT | |
| Simplify Treasury Option Income ETF | Government Bonds, Ultrashort Bond, Derivative Income | 96 | 2.42% | 474.96M | Oct 2022 | PINK vs BUCK | |
| Simplify Bitcoin Strategy PLUS Income ETF | Cryptocurrency, Derivative Income | 1 | -33.30% | 25.97M | Sep 2022 | PINK vs MAXI | |
| Simplify Interest Rate Hedge ETF | Hedge Fund | 5 | -0.06% | 167.19M | May 2021 | PINK vs PFIX | |
| Simplify High Yield ETF | High Yield Bonds | 7 | -2.44% | 387.11M | Feb 2022 | PINK vs CDX | |
| Simplify Enhanced Income ETF | Derivative Income, Dividend | 6 | -0.61% | 71.03M | Oct 2022 | PINK vs HIGH | |
| Simplify Aggregate Bond ETF | Intermediate Core Bond | 52 | 0.62% | 570.38M | Feb 2022 | PINK vs AGGH | |
| Simplify MBS ETF | Mortgage Backed Securities | 45 | 0.02% | 1.53B | Nov 2023 | PINK vs MTBA |
Often Compared With PINK
Investors most often compare PINK with PPH, ^GSPC, ^SP500TR. These 20 comparison targets span 6 categories, based on PortfoliosLab usage data.
Compare PINK with Any Fund or Stock
Compare PINK with any ETF, mutual fund, or stock using PortfoliosLab's comparison tool.
Pair PINK with funds that move differently
Simplify Health Care ETF alternatives help with substitution. Diversifiers are the next step when you want funds with lower historical correlation to PINK.
Explore PINK Diversifiers