ROBO Global Healthcare Technology and Innovation ETF (HTEC) belongs to the Health & Biotech Equities category. Below you'll find alternative ETFs from the same category, ranked by key criteria, plus funds that investors commonly compare with HTEC. Use the tables to find lower-cost options, better risk-adjusted returns, or a closer substitute for your current allocation.
Cheapest Alternatives to HTEC
HTEC charges 0.68% annually. There are 42 ETFs in the Health & Biotech Equities category with lower expense ratios, going as low as 0.08%.
| Symbol | Name | Expense Ratio | AUM | Inception | |
|---|---|---|---|---|---|
| Fidelity MSCI Health Care Index ETF | 0.08% | 2.85B | Oct 2013 | HTEC vs FHLC | |
| State Street Health Care Select Sector SPDR ETF | 0.08% | 38.66B | Dec 1998 | HTEC vs XLV | |
| Vanguard Health Care ETF | 0.09% | 18.50B | Jan 2004 | HTEC vs VHT | |
| Portfolio Building Block World Pharma and Biotech ... | 0.13% | 9.98M | Nov 2025 | HTEC vs PBPH | |
| Invesco S&P SmallCap Health Care ETF | 0.29% | 131.36M | Apr 2010 | HTEC vs PSCH |
Best Risk-Adjusted Alternatives to HTEC
HTEC has a PortfoliosLab risk / return rank of 34. There are 27 ETFs in the Health & Biotech Equities category with higher risk-adjusted ranks, going as high as 89.
| Symbol | Name | Risk / Return Rank | AUM | Inception | |
|---|---|---|---|---|---|
| Virtus LifeSci Biotech Clinical Trials ETF | 89 | 43.63M | Dec 2014 | HTEC vs BBC | |
| SPDR S&P Biotech ETF | 74 | 8.28B | Feb 2006 | HTEC vs XBI | |
| iShares U.S. Pharmaceuticals ETF | 74 | 912.87M | May 2006 | HTEC vs IHE | |
| ALPS Medical Breakthroughs ETF | 72 | 161.79M | Dec 2014 | HTEC vs SBIO | |
| First Trust Nasdaq Pharmaceuticals ETF | 71 | 35.04M | Sep 2016 | HTEC vs FTXH |
Top Performing HTEC Alternatives (YTD)
HTEC is at -2.96% YTD. There are 37 ETFs in the Health & Biotech Equities category with higher YTD returns, going as high as 20.15%.
| Symbol | Name | YTD Return | AUM | Inception | |
|---|---|---|---|---|---|
| AdvisorShares Psychedelics ETF | 20.15% | 35.56M | Sep 2021 | HTEC vs PSIL | |
| ARK Genomic Revolution Multi-Sector ETF | 17.09% | 1.24B | Oct 2014 | HTEC vs ARKG | |
| Roundhill UNH WeeklyPay ETF | 15.08% | 4.48M | Dec 2025 | HTEC vs UNHW | |
| iShares Genomics Immunology and Healthcare ETF Gen... | 10.31% | 163.14M | Jun 2019 | HTEC vs IDNA | |
| Virtus LifeSci Biotech Clinical Trials ETF | 8.64% | 43.63M | Dec 2014 | HTEC vs BBC |
Lowest Volatility Alternatives to HTEC
HTEC has 20.32% 1-year volatility. There are 36 ETFs in the Health & Biotech Equities category with lower 1-year volatility, going as low as 0.00%.
| Symbol | Name | Volatility 1Y | AUM | Inception | |
|---|---|---|---|---|---|
| Principal Healthcare Innovators Index ETF | 0.00% | 16.16M | Aug 2016 | HTEC vs BTEC | |
| Amplify Treatments, Testing and Advancements ETF | 0.00% | 9.68M | Jun 2020 | HTEC vs GERM | |
| Loncar Cancer Immunotherapy ETF | 0.00% | 12.73M | Oct 2015 | HTEC vs CNCR | |
| Horizon Kinetics SPAC Active ETF | 8.80% | 10.01M | Jun 2007 | HTEC vs SPAQ | |
| State Street Health Care Select Sector SPDR Premiu... | 10.94% | 14.25M | Jul 2025 | HTEC vs XLVI |
Lowest Drawdown Alternatives to HTEC
HTEC has a 1-year max drawdown of -16.31%. There are 40 ETFs in the Health & Biotech Equities category with shallower 1-year drawdowns, going as shallow as 0.00%.
| Symbol | Name | Max Drawdown 1Y | AUM | Inception | |
|---|---|---|---|---|---|
| Amplify Treatments, Testing and Advancements ETF | 0.00% | 9.68M | Jun 2020 | HTEC vs GERM | |
| Horizon Kinetics SPAC Active ETF | -5.30% | 10.01M | Jun 2007 | HTEC vs SPAQ | |
| First Trust Nasdaq Pharmaceuticals ETF | -7.47% | 35.04M | Sep 2016 | HTEC vs FTXH | |
| Invesco Nasdaq Biotechnology ETF | -8.34% | 67.37M | Jun 2021 | HTEC vs IBBQ | |
| iShares U.S. Pharmaceuticals ETF | -8.47% | 912.87M | May 2006 | HTEC vs IHE |
Other ETFs from Exchange Traded Concepts
The 10 most viewed Exchange Traded Concepts ETFs shown here include NUKZ, URNM, ROBO and span 11 categories. AUM among these funds goes as high as $2B.
| Symbol | Name | Category | Risk / Return Rank | YTD Return | AUM | Inception | |
|---|---|---|---|---|---|---|---|
| Range Nuclear Renaissance ETF | Energy Equities | 40 | 13.31% | 832.38M | Jan 2024 | HTEC vs NUKZ | |
| NorthShore Global Uranium Mining ETF | Commodity Producers Equities | 29 | 11.97% | 2.21B | Dec 2019 | HTEC vs URNM | |
| ROBO Global Robotics & Automation Index ETF | Robotics, Technology Equities | 72 | 29.33% | 1.84B | Oct 2013 | HTEC vs ROBO | |
| Saba Closed-End Funds ETF | Event Driven | 80 | 13.75% | 332.90M | Mar 2017 | HTEC vs CEFS | |
| Bitwise Crypto Industry Innovators ETF | Technology Equities, Blockchain | 28 | 39.79% | 501.54M | May 2021 | HTEC vs BITQ | |
| ROBO Global Artificial Intelligence ETF | Technology Equities | 80 | 44.05% | 305.95M | May 2020 | HTEC vs THNQ | |
| Hull Tactical US ETF | Long-Short | 78 | 11.33% | 137.43M | Jun 2015 | HTEC vs HTUS | |
| QRAFT AI-Enhanced U.S. Large Cap Momentum ETF | Momentum, Large Cap Growth Equities | 60 | 27.93% | 33.44M | May 2019 | HTEC vs AMOM | |
| EMQQ The Emerging Markets Internet ETF | Emerging Markets Equities | 3 | -19.80% | 405.00M | Nov 2014 | HTEC vs EMQQ | |
| Nifty India Financials ETF | Financials Equities | — | — | 10.83M | Oct 2020 | HTEC vs INDF |
Often Compared With HTEC
Investors most often compare HTEC with WTAI, MDEV, HEAL. These 20 comparison targets span 13 categories, based on PortfoliosLab usage data.
Compare HTEC with Any Fund or Stock
Compare HTEC with any ETF, mutual fund, or stock using PortfoliosLab's comparison tool.
Pair HTEC with funds that move differently
ROBO Global Healthcare Technology and Innovation ETF alternatives help with substitution. Diversifiers are the next step when you want funds with lower historical correlation to HTEC.
Explore HTEC Diversifiers