HTEC vs. SBIO

Last updated Jun 4, 2026

HTEC (ROBO Global Healthcare Technology and Innovation ETF) and SBIO (ALPS Medical Breakthroughs ETF) are both Health & Biotech Equities funds - HTEC tracks the ROBO Global® Healthcare Technology and Innovation Index while SBIO tracks the S-Network Medical Breakthroughs Index. Both are passively managed. Over the past 5 years, HTEC returned -4.88%/yr vs 2.68%/yr for SBIO. A 0.72 correlation means they provide meaningful diversification when combined. HTEC charges 0.68%/yr vs 0.50%/yr for SBIO.

Performance

HTEC vs. SBIO - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in ROBO Global Healthcare Technology and Innovation ETF (HTEC) and ALPS Medical Breakthroughs ETF (SBIO). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, HTEC achieves a -2.96% return, which is significantly lower than SBIO's -0.39% return.

HTEC

• 1D: 0.67%
• 1M: 3.12%
• YTD: -2.96%
• 6M: -3.90%
• 1Y: 26.68%
• 3Y*: 5.17%
• 5Y*: -4.88%
• 10Y*: —

SBIO

• 1D: 1.41%
• 1M: -7.56%
• YTD: -0.39%
• 6M: 3.05%
• 1Y: 65.41%
• 3Y*: 17.80%
• 5Y*: 2.68%
• 10Y*: 8.02%

*Multi-year figures are annualized to reflect compound growth (CAGR)

HTEC vs. SBIO - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019
HTEC ROBO Global Healthcare Technology and Innovation ETF	-2.96%	23.91%	2.68%	-2.94%	-33.72%	-0.28%	65.01%	9.34%
SBIO ALPS Medical Breakthroughs ETF	-0.39%	55.07%	3.81%	8.68%	-28.08%	-17.55%	21.17%	20.50%

Correlation

The correlation between HTEC and SBIO is 0.58, which is moderate. They share some common price drivers but move independently often enough to provide real diversification benefit when combined.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.58
Correlation (3Y) Calculated over the trailing 3-year period	0.65
Correlation (5Y) Calculated over the trailing 5-year period	0.71
Correlation (All Time) Calculated using the full available price history since Jun 26, 2019	0.72

The correlation between HTEC and SBIO shifts across timeframes, from 0.58 (1 year) to 0.72 (all time), reflecting how their relationship changes across market environments.

HTEC vs. SBIO - Sectors Allocation Comparison

Sectors	HTEC	SBIO
Healthcare	77.3%	100.0%
Financial Services	3.9%	-0.0%
Technology	3.7%	-
Industrials	1.3%	-
Energy	1.2%	-
Basic Materials	-	-
Communication Services	-	-
Consumer Cyclical	-	-
Consumer Defensive	-	-
Real Estate	-	-
Utilities	-	-

Return for Risk

HTEC vs. SBIO — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

HTEC

HTEC Risk / Return Rank: 34
HTEC Sharpe Ratio Rank: 36
HTEC Sortino Ratio Rank: 38
HTEC Omega Ratio Rank: 33
HTEC Calmar Ratio Rank: 33
HTEC Martin Ratio Rank: 29

SBIO

SBIO Risk / Return Rank: 72
SBIO Sharpe Ratio Rank: 67
SBIO Sortino Ratio Rank: 67
SBIO Omega Ratio Rank: 59
SBIO Calmar Ratio Rank: 88
SBIO Martin Ratio Rank: 79

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

HTEC vs. SBIO - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for ROBO Global Healthcare Technology and Innovation ETF (HTEC) and ALPS Medical Breakthroughs ETF (SBIO). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	HTEC	SBIO	Difference
Sharpe ratio: Return per unit of total volatility	1.32	2.24	-0.92
Sortino ratio: Return per unit of downside risk	1.99	3.10	-1.12
Omega ratio: Gain probability vs. loss probability	1.23	1.36	-0.13
Calmar ratio: Return relative to maximum drawdown	1.64	5.19	-3.55
Martin ratio: Return relative to average drawdown	4.07	15.57	-11.49
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

HTEC vs. SBIO - Sharpe Ratio Comparison

The current HTEC Sharpe Ratio is 1.32, which is lower than the SBIO Sharpe Ratio of 2.24. The chart below compares the historical Sharpe Ratios of HTEC and SBIO, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Sharpe Ratios by Period

	HTEC	SBIO	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	1.32	2.24	-0.92
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	-0.20	0.08	-0.28
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	—	0.24	—
Sharpe Ratio (All Time) Calculated using the full available price history	0.21	0.21	-0.01

Drawdowns

HTEC vs. SBIO - Drawdown Comparison

The maximum HTEC drawdown since its inception was -57.53%, smaller than the maximum SBIO drawdown of -63.06%. Use the drawdown chart below to compare losses from any high point for HTEC and SBIO.

Drawdown Indicators

	HTEC	SBIO	Difference
Max Drawdown Largest peak-to-trough decline	-57.53%	-63.06%	+5.53%
Max Drawdown (1Y) Largest decline over 1 year	-16.31%	-12.66%	-3.65%
Max Drawdown (3Y) Largest decline over 3 years	-28.67%	-42.44%	+13.77%
Max Drawdown (5Y) Largest decline over 5 years	-56.10%	-53.10%	-3.00%
Max Drawdown (10Y) Largest decline over 10 years	—	-63.06%	—
Current Drawdown Current decline from peak	-33.25%	-16.79%	-16.46%
Average Drawdown Average peak-to-trough decline	-28.99%	-28.45%	-0.54%
Ulcer Index Depth and duration of drawdowns from previous peaks	6.57%	4.22%	+2.35%

Volatility

HTEC vs. SBIO - Volatility Comparison

The current volatility for ROBO Global Healthcare Technology and Innovation ETF (HTEC) is 5.82%, while ALPS Medical Breakthroughs ETF (SBIO) has a volatility of 9.48%. This indicates that HTEC experiences smaller price fluctuations and is considered to be less risky than SBIO based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	HTEC	SBIO	Difference
Volatility (1M) Calculated over the trailing 1-month period	5.82%	9.48%	-3.66%
Volatility (6M) Calculated over the trailing 6-month period	14.90%	22.70%	-7.80%
Volatility (1Y) Calculated over the trailing 1-year period	20.32%	29.42%	-9.10%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	24.39%	33.56%	-9.17%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	25.46%	33.17%	-7.71%

HTEC vs. SBIO - Expense Ratio Comparison

HTEC has a 0.68% expense ratio, which is higher than SBIO's 0.50% expense ratio.

Dividends

HTEC vs. SBIO - Dividend Comparison

HTEC's dividend yield for the trailing twelve months is around 1.01%, while SBIO has not paid dividends to shareholders.

Position	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017
HTEC ROBO Global Healthcare Technology and Innovation ETF	1.01%	0.98%	0.00%	0.00%	0.00%	0.05%	0.00%	0.00%	0.00%	0.00%
SBIO ALPS Medical Breakthroughs ETF	0.00%	0.00%	3.55%	0.22%	0.00%	0.00%	0.00%	0.04%	2.79%	1.77%

Frequently Asked Questions

Can I hold both HTEC and SBIO in my portfolio?

HTEC and SBIO have a correlation of 0.58, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, HTEC or SBIO?

SBIO has higher volatility (9.48%) compared to HTEC (5.82%). In terms of maximum drawdown, HTEC dropped -57.53% vs SBIO's -63.06%.

Which ETF is better, HTEC or SBIO?

On 5-year performance, SBIO leads with 2.68% vs -4.88% for HTEC. On fees, SBIO is cheaper at 0.50% per year. On volatility, HTEC has been the lower-risk option at 5.82%. The better choice depends on whether you care most about return, fees, risk, or income.

Which ETF has performed better, HTEC or SBIO?

Over the 5-year period, SBIO has performed better with a 2.68% return vs -4.88%. Past performance does not guarantee future results, so compare this with risk, fees, and fund exposure.

Which ETF is cheaper, HTEC or SBIO?

SBIO is cheaper with a 0.50% expense ratio, compared with 0.68% for HTEC.

Which ETF pays a higher dividend yield, HTEC or SBIO?

HTEC has the higher dividend yield at 1.01%, compared with 0.00% for SBIO.

What is the main difference between HTEC and SBIO?

HTEC tracks ROBO Global® Healthcare Technology and Innovation Index, while SBIO tracks S-Network Medical Breakthroughs Index. They also come from different issuers: Exchange Traded Concepts and SS&C. Their fees differ too: 0.68% for HTEC and 0.50% for SBIO.

Which has better risk-adjusted returns?

SBIO currently has the higher Sharpe Ratio (2.24 vs 1.32), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.