Goldman Sachs Future Health Care Equity ETF (GDOC) belongs to the Health & Biotech Equities category. Below you'll find alternative ETFs from the same category, ranked by key criteria, plus funds that investors commonly compare with GDOC. Use the tables to find lower-cost options, better risk-adjusted returns, or a closer substitute for your current allocation.
Cheapest Alternatives to GDOC
GDOC charges 0.75% annually. There are 46 ETFs in the Health & Biotech Equities category with lower expense ratios, going as low as 0.08%.
| Symbol | Name | Expense Ratio | AUM | Inception | |
|---|---|---|---|---|---|
| Fidelity MSCI Health Care Index ETF | 0.08% | 2.99B | Oct 2013 | GDOC vs FHLC | |
| State Street Health Care Select Sector SPDR ETF | 0.08% | 38.47B | Dec 1998 | GDOC vs XLV | |
| Vanguard Health Care ETF | 0.09% | 19.00B | Jan 2004 | GDOC vs VHT | |
| Portfolio Building Block World Pharma and Biotech ... | 0.13% | 9.98M | Nov 2025 | GDOC vs PBPH | |
| GSK plc ADRhedged ETF | 0.19% | 793.18K | Jan 2025 | GDOC vs GSKH |
Best Risk-Adjusted Alternatives to GDOC
GDOC has a PortfoliosLab risk / return rank of 17. There are 48 ETFs in the Health & Biotech Equities category with higher risk-adjusted ranks, going as high as 95.
| Symbol | Name | Risk / Return Rank | AUM | Inception | |
|---|---|---|---|---|---|
| Virtus LifeSci Biotech Clinical Trials ETF | 95 | 40.93M | Dec 2014 | GDOC vs BBC | |
| ALPS Medical Breakthroughs ETF | 92 | 160.12M | Dec 2014 | GDOC vs SBIO | |
| SPDR S&P Biotech ETF | 90 | 8.62B | Feb 2006 | GDOC vs XBI | |
| iShares Neuroscience and Healthcare ETF | 89 | 5.39M | Aug 2022 | GDOC vs IBRN | |
| First Trust Nasdaq Pharmaceuticals ETF | 87 | 33.60M | Sep 2016 | GDOC vs FTXH |
Top Performing GDOC Alternatives (YTD)
GDOC is at -4.32% YTD. There are 53 ETFs in the Health & Biotech Equities category with higher YTD returns, going as high as 27.05%.
| Symbol | Name | YTD Return | AUM | Inception | |
|---|---|---|---|---|---|
| Roundhill UNH WeeklyPay ETF | 27.05% | 4.79M | Dec 2025 | GDOC vs UNHW | |
| Virtus LifeSci Biotech Clinical Trials ETF | 25.75% | 40.93M | Dec 2014 | GDOC vs BBC | |
| AdvisorShares Psychedelics ETF | 25.04% | 33.07M | Sep 2021 | GDOC vs PSIL | |
| ARK Genomic Revolution Multi-Sector ETF | 24.30% | 1.31B | Oct 2014 | GDOC vs ARKG | |
| SPDR S&P Biotech ETF | 20.70% | 8.62B | Feb 2006 | GDOC vs XBI |
Lowest Volatility Alternatives to GDOC
GDOC has 15.93% 1-year volatility. There are 13 ETFs in the Health & Biotech Equities category with lower 1-year volatility, going as low as 0.00%.
| Symbol | Name | Volatility 1Y | AUM | Inception | |
|---|---|---|---|---|---|
| Loncar Cancer Immunotherapy ETF | 0.00% | 12.73M | Oct 2015 | GDOC vs CNCR | |
| Amplify Treatments, Testing and Advancements ETF | 0.00% | 9.68M | Jun 2020 | GDOC vs GERM | |
| Horizon Kinetics SPAC Active ETF | 8.65% | 10.10M | Jun 2007 | GDOC vs SPAQ | |
| State Street Health Care Select Sector SPDR Premiu... | 11.06% | 14.95M | Jul 2025 | GDOC vs XLVI | |
| Global X Aging Population ETF | 13.70% | 80.19M | May 2016 | GDOC vs AGNG |
Lowest Drawdown Alternatives to GDOC
GDOC has a 1-year max drawdown of -15.67%. There are 38 ETFs in the Health & Biotech Equities category with shallower 1-year drawdowns, going as shallow as 0.00%.
| Symbol | Name | Max Drawdown 1Y | AUM | Inception | |
|---|---|---|---|---|---|
| Amplify Treatments, Testing and Advancements ETF | 0.00% | 9.68M | Jun 2020 | GDOC vs GERM | |
| Horizon Kinetics SPAC Active ETF | -5.00% | 10.10M | Jun 2007 | GDOC vs SPAQ | |
| First Trust Nasdaq Pharmaceuticals ETF | -7.47% | 33.60M | Sep 2016 | GDOC vs FTXH | |
| Invesco Nasdaq Biotechnology ETF | -8.34% | 68.94M | Jun 2021 | GDOC vs IBBQ | |
| iShares U.S. Pharmaceuticals ETF | -8.47% | 956.44M | May 2006 | GDOC vs IHE |
Other ETFs from Goldman Sachs
The 10 most viewed Goldman Sachs ETFs shown here include GPIQ, GPIX, AAAU and span 13 categories. AUM among these funds goes as high as $15B.
Often Compared With GDOC
Investors most often compare GDOC with GGUS, PJP, LFSC. These 20 comparison targets span 7 categories, based on PortfoliosLab usage data.
Compare GDOC with Any Fund or Stock
Compare GDOC with any ETF, mutual fund, or stock using PortfoliosLab's comparison tool.
Pair GDOC with funds that move differently
Goldman Sachs Future Health Care Equity ETF alternatives help with substitution. Diversifiers are the next step when you want funds with lower historical correlation to GDOC.
Explore GDOC Diversifiers