Global X Aging Population ETF (AGNG) belongs to the Health & Biotech Equities category. Below you'll find alternative ETFs from the same category, ranked by key criteria, plus funds that investors commonly compare with AGNG. Use the tables to find lower-cost options, better risk-adjusted returns, or a closer substitute for your current allocation.
Cheapest Alternatives to AGNG
AGNG charges 0.50% annually. There are 25 ETFs in the Health & Biotech Equities category with lower expense ratios, going as low as 0.08%.
| Symbol | Name | Expense Ratio | AUM | Inception | |
|---|---|---|---|---|---|
| Fidelity MSCI Health Care Index ETF | 0.08% | 3.22B | Oct 2013 | AGNG vs FHLC | |
| State Street Health Care Select Sector SPDR ETF | 0.08% | 41.65B | Dec 1998 | AGNG vs XLV | |
| Vanguard Health Care ETF | 0.09% | 19.00B | Jan 2004 | AGNG vs VHT | |
| Portfolio Building Block World Pharma and Biotech ... | 0.13% | 951.16M | Nov 2025 | AGNG vs PBPH | |
| Invesco Nasdaq Biotechnology ETF | 0.19% | 74.65M | Jun 2021 | AGNG vs IBBQ |
Best Risk-Adjusted Alternatives to AGNG
AGNG has a PortfoliosLab risk / return rank of 34. There are 44 ETFs in the Health & Biotech Equities category with higher risk-adjusted ranks, going as high as 96.
| Symbol | Name | Risk / Return Rank | AUM | Inception | |
|---|---|---|---|---|---|
| Virtus LifeSci Biotech Clinical Trials ETF | 96 | 57.56M | Dec 2014 | AGNG vs BBC | |
| ALPS Medical Breakthroughs ETF | 94 | 213.08M | Dec 2014 | AGNG vs SBIO | |
| iShares U.S. Pharmaceuticals ETF | 94 | 1.34B | May 2006 | AGNG vs IHE | |
| First Trust Nasdaq Pharmaceuticals ETF | 94 | 36.36M | Sep 2016 | AGNG vs FTXH | |
| SPDR S&P Biotech ETF | 94 | 11.10B | Feb 2006 | AGNG vs XBI |
Top Performing AGNG Alternatives (YTD)
AGNG is at 2.71% YTD. There are 50 ETFs in the Health & Biotech Equities category with higher YTD returns, going as high as 40.54%.
| Symbol | Name | YTD Return | AUM | Inception | |
|---|---|---|---|---|---|
| AdvisorShares Psychedelics ETF | 40.54% | 44.37M | Sep 2021 | AGNG vs PSIL | |
| ARK Genomic Revolution Multi-Sector ETF | 37.63% | 1.31B | Oct 2014 | AGNG vs ARKG | |
| Roundhill UNH WeeklyPay ETF | 33.20% | 6.01M | Dec 2025 | AGNG vs UNHW | |
| Virtus LifeSci Biotech Clinical Trials ETF | 32.18% | 57.56M | Dec 2014 | AGNG vs BBC | |
| ALPS Medical Breakthroughs ETF | 27.29% | 213.08M | Dec 2014 | AGNG vs SBIO |
Lowest Volatility Alternatives to AGNG
AGNG has 14.10% 1-year volatility. There are 5 ETFs in the Health & Biotech Equities category with lower 1-year volatility, going as low as 0.00%.
| Symbol | Name | Volatility 1Y | AUM | Inception | |
|---|---|---|---|---|---|
| Loncar Cancer Immunotherapy ETF | 0.00% | 12.73M | Oct 2015 | AGNG vs CNCR | |
| Amplify Treatments, Testing and Advancements ETF | 0.00% | 9.68M | Jun 2020 | AGNG vs GERM | |
| Horizon Kinetics SPAC Active ETF | 8.62% | 10.11M | Jun 2007 | AGNG vs SPAQ | |
| State Street Health Care Select Sector SPDR Premiu... | 11.04% | 16.78M | Jul 2025 | AGNG vs XLVI | |
| Milliman Healthcare Inflation Plus ETF | 11.46% | 982.35K | Apr 2026 | AGNG vs MHIP |
Lowest Drawdown Alternatives to AGNG
AGNG has a 1-year max drawdown of -11.45%. There are 24 ETFs in the Health & Biotech Equities category with shallower 1-year drawdowns, going as shallow as 0.00%.
| Symbol | Name | Max Drawdown 1Y | AUM | Inception | |
|---|---|---|---|---|---|
| Amplify Treatments, Testing and Advancements ETF | 0.00% | 9.68M | Jun 2020 | AGNG vs GERM | |
| Horizon Kinetics SPAC Active ETF | -4.32% | 10.11M | Jun 2007 | AGNG vs SPAQ | |
| First Trust Nasdaq Pharmaceuticals ETF | -7.47% | 36.36M | Sep 2016 | AGNG vs FTXH | |
| Invesco Nasdaq Biotechnology ETF | -8.34% | 74.65M | Jun 2021 | AGNG vs IBBQ | |
| iShares U.S. Pharmaceuticals ETF | -8.47% | 1.34B | May 2006 | AGNG vs IHE |
Other ETFs from Global X
The 10 most viewed Global X ETFs shown here include QYLD, SHLD, AIQ and span 12 categories. AUM among these funds goes as high as $14B.
| Symbol | Name | Category | Risk / Return Rank | YTD Return | AUM | Inception | |
|---|---|---|---|---|---|---|---|
| Global X NASDAQ 100 Covered Call ETF | Nasdaq-100, Derivative Income | 80 | 7.05% | 8.37B | Dec 2013 | AGNG vs QYLD | |
| Global X Defense Tech ETF | Aerospace & Defense | 9 | -7.00% | 6.91B | Sep 2023 | AGNG vs SHLD | |
| Global X Artificial Intelligence & Technology ETF | Technology Equities | 41 | 15.42% | 10.08B | May 2018 | AGNG vs AIQ | |
| Global X Uranium ETF | Uranium | 11 | -9.36% | 5.92B | Nov 2010 | AGNG vs URA | |
| Global X Copper Miners ETF | Copper | 55 | 2.52% | 6.98B | Apr 2010 | AGNG vs COPX | |
| Global X Robotics & Artificial Intelligence Themat... | Robotics, Technology Equities | 12 | -5.00% | 3.44B | Sep 2016 | AGNG vs BOTZ | |
| Global X Silver Miners ETF | Silver, Precious Metals | 30 | -13.99% | 4.14B | Apr 2010 | AGNG vs SIL | |
| Global X S&P 500 Covered Call ETF | Derivative Income, S&P 500 | 89 | 6.93% | 3.22B | Jun 2013 | AGNG vs XYLD | |
| Global X Data Center & Digital Infrastructure ETF | REIT | 67 | 30.34% | 2.25B | Oct 2020 | AGNG vs DTCR | |
| Global X US Infrastructure Development ETF | Industrials Equities | 47 | 18.01% | 14.01B | Mar 2017 | AGNG vs PAVE |
Often Compared With AGNG
Investors most often compare AGNG with AGES.L, WDNA, SPY. These 20 comparison targets span 6 categories, based on PortfoliosLab usage data.
Compare AGNG with Any Fund or Stock
Compare AGNG with any ETF, mutual fund, or stock using PortfoliosLab's comparison tool.
Pair AGNG with funds that move differently
Global X Aging Population ETF alternatives help with substitution. Diversifiers are the next step when you want funds with lower historical correlation to AGNG.
Explore AGNG Diversifiers