AGNG vs. GERM

Last updated Jun 25, 2026

AGNG (Global X Aging Population ETF) and GERM (Amplify Treatments, Testing and Advancements ETF) are both Health & Biotech Equities funds - AGNG tracks the Indxx Aging Population Thematic Index while GERM tracks the Prime Treatments, Testing and Advancements Index. Both are passively managed. Over the past year, AGNG returned 12.38% vs 0.00% for GERM. AGNG charges 0.50%/yr vs 0.68%/yr for GERM.

Performance

AGNG vs. GERM - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Global X Aging Population ETF (AGNG) and Amplify Treatments, Testing and Advancements ETF (GERM). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

AGNG

• 1D: 1.39%
• 1M: -1.10%
• YTD: -1.30%
• 6M: -2.50%
• 1Y: 12.38%
• 3Y*: 9.44%
• 5Y*: 3.58%
• 10Y*: 9.52%

GERM

• 1D: 0.00%
• 1M: 0.00%
• YTD: 0.00%
• 6M: 0.00%
• 1Y: 0.00%
• 3Y*: —
• 5Y*: —
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

AGNG vs. GERM - Yearly Performance Comparison

	2026 (YTD)	2025	2024
AGNG Global X Aging Population ETF	-1.30%	20.01%	-6.40%
GERM Amplify Treatments, Testing and Advancements ETF	0.00%	0.00%	0.00%

AGNG vs. GERM - Sectors Allocation Comparison

Sectors	AGNG	GERM
Healthcare	91.2%	99.3%
Real Estate	8.9%	-
Basic Materials	-	-
Communication Services	-	-
Consumer Cyclical	-	-
Consumer Defensive	-	-
Energy	-	-
Financial Services	-	0.4%
Industrials	-	-
Technology	-	-
Utilities	-	-

Return for Risk

AGNG vs. GERM — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

AGNG

AGNG Risk / Return Rank: 26
AGNG Sharpe Ratio Rank: 28
AGNG Sortino Ratio Rank: 28
AGNG Omega Ratio Rank: 26
AGNG Calmar Ratio Rank: 25
AGNG Martin Ratio Rank: 23

GERM

Risk / return metrics aren't available yet — we need at least 12 months of trading data to calculate them.

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

AGNG vs. GERM - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Global X Aging Population ETF (AGNG) and Amplify Treatments, Testing and Advancements ETF (GERM). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.

	AGNG	GERM	Difference
Sharpe ratio: Return per unit of total volatility	0.91	—	—
Sortino ratio: Return per unit of downside risk	1.39	—	—
Omega ratio: Gain probability vs. loss probability	1.17	—	—
Calmar ratio: Return relative to maximum drawdown	1.09	—	—
Martin ratio: Return relative to average drawdown	2.64	—	—

Drawdowns

AGNG vs. GERM - Drawdown Comparison

The maximum AGNG drawdown since its inception was -30.58%, which is greater than GERM's maximum drawdown of 0.00%. Use the drawdown chart below to compare losses from any high point for AGNG and GERM.

Drawdown Indicators

	AGNG	GERM	Difference
Max Drawdown Largest peak-to-trough decline	-30.58%	0.00%	-30.58%
Max Drawdown (1Y) Largest decline over 1 year	-11.45%	0.00%	-11.45%
Max Drawdown (3Y) Largest decline over 3 years	-14.48%	—	—
Max Drawdown (5Y) Largest decline over 5 years	-25.66%	—	—
Max Drawdown (10Y) Largest decline over 10 years	-30.58%	—	—
Current Drawdown Current decline from peak	-7.83%	0.00%	-7.83%
Average Drawdown Average peak-to-trough decline	-5.97%	0.00%	-5.97%
Ulcer Index Depth and duration of drawdowns from previous peaks	4.71%	0.00%	+4.71%

Volatility

AGNG vs. GERM - Volatility Comparison

Global X Aging Population ETF (AGNG) has a higher volatility of 4.46% compared to Amplify Treatments, Testing and Advancements ETF (GERM) at 0.00%. This indicates that AGNG's price experiences larger fluctuations and is considered to be riskier than GERM based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	AGNG	GERM	Difference
Volatility (1M) Calculated over the trailing 1-month period	4.46%	0.00%	+4.46%
Volatility (6M) Calculated over the trailing 6-month period	10.37%	0.00%	+10.37%
Volatility (1Y) Calculated over the trailing 1-year period	13.75%	0.00%	+13.75%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	15.24%	0.00%	+15.24%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	17.14%	0.00%	+17.14%

AGNG vs. GERM - Expense Ratio Comparison

AGNG has a 0.50% expense ratio, which is lower than GERM's 0.68% expense ratio.

Dividends

AGNG vs. GERM - Dividend Comparison

AGNG's dividend yield for the trailing twelve months is around 0.89%, while GERM has not paid dividends to shareholders.

Position	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016
AGNG Global X Aging Population ETF	0.89%	0.88%	0.83%	0.96%	0.49%	0.72%	0.36%	0.83%	1.00%	1.04%	0.45%
GERM Amplify Treatments, Testing and Advancements ETF	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%

Frequently Asked Questions

Which is riskier, AGNG or GERM?

AGNG has higher volatility (4.46%) compared to GERM (0.00%). In terms of maximum drawdown, AGNG dropped -30.58% vs GERM's 0.00%.

Which ETF is better, AGNG or GERM?

On 1-year performance, AGNG leads with 12.38% vs 0.00% for GERM. On fees, AGNG is cheaper at 0.50% per year. On volatility, GERM has been the lower-risk option at 0.00%. The better choice depends on whether you care most about return, fees, risk, or income.

Which ETF has performed better, AGNG or GERM?

Over the 1-year period, AGNG has performed better with a 12.38% return vs 0.00%. Past performance does not guarantee future results, so compare this with risk, fees, and fund exposure.

Which ETF is cheaper, AGNG or GERM?

AGNG is cheaper with a 0.50% expense ratio, compared with 0.68% for GERM.

Which ETF pays a higher dividend yield, AGNG or GERM?

AGNG has the higher dividend yield at 0.89%, compared with 0.00% for GERM.

What is the main difference between AGNG and GERM?

AGNG tracks Indxx Aging Population Thematic Index, while GERM tracks Prime Treatments, Testing and Advancements Index. They also come from different issuers: Global X and Amplify. Their fees differ too: 0.50% for AGNG and 0.68% for GERM.