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ARWR vs. ALNY
Performance
Return for Risk
Drawdowns
Volatility
Dividends
Financials

Performance

ARWR vs. ALNY - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Arrowhead Pharmaceuticals, Inc. (ARWR) and Alnylam Pharmaceuticals, Inc. (ALNY). The values are adjusted to include any dividend payments, if applicable.

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Returns By Period

In the year-to-date period, ARWR achieves a 27.50% return, which is significantly higher than ALNY's -48.32% return. Over the past 10 years, ARWR has outperformed ALNY with an annualized return of 30.88%, while ALNY has yielded a comparatively lower 11.28% annualized return.


ARWR

1D
-3.06%
1M
0.79%
6M
22.10%
YTD
27.50%
1Y
431.39%
3Y*
35.96%
5Y*
4.09%
10Y*
30.88%
ALL TIME*
-0.69%

ALNY

1D
0.02%
1M
-34.29%
6M
-39.21%
YTD
-48.32%
1Y
-48.85%
3Y*
2.82%
5Y*
2.81%
10Y*
11.28%
ALL TIME*
17.20%
*Multi-year figures are annualized to reflect compound growth (CAGR)

Liquidity Comparison


PositionAvg. Volume Value (2W)Avg. Volume Value (1M)Avg. Volume Value (3M)
$567.18M$557.43M$409.61M
$205.45M$188.79M$175.31M

ARWR vs. ALNY - Yearly Performance Comparison


2026 (YTD)202520242023202220212020201920182017
ARWR
Arrowhead Pharmaceuticals, Inc.
27.50%253.14%-38.56%-24.56%-38.82%-13.59%20.97%410.71%237.50%137.42%
ALNY
Alnylam Pharmaceuticals, Inc.
-48.32%68.99%22.94%-19.46%40.14%30.48%12.85%57.96%-42.61%239.34%

Correlation

The correlation between ARWR and ALNY is 0.23, which is low. Their historical price movements had little consistent relationship.


Correlation
Correlation (1Y)
Focuses on recent behavior, but can change the most.

0.23

Correlation (3Y)
Balances recent behavior with more history.

0.30

Correlation (5Y)
Shows whether the relationship held over a longer period.

0.41

Correlation (10Y)
Provides a long-term view across more market conditions.

0.39

Correlation (All Time)
Calculated using the full available price history since Jun 1, 2004

0.29

The correlation between ARWR and ALNY shifts across timeframes, from 0.23 (1 year) to 0.41 (5 years), reflecting how their relationship changes across market environments.

Fundamentals

Market Cap

ARWR:

$11.92B

ALNY:

$27.44B

EPS

ARWR:

-$2.16

ALNY:

$5.88

PS Ratio

ARWR:

19.00

ALNY:

5.88

PB Ratio

ARWR:

20.13

ALNY:

20.98

Total Revenue (TTM)

ARWR:

$622.01M

ALNY:

$4.80B

Gross Profit (TTM)

ARWR:

$529.27M

ALNY:

$1.88B

EBITDA (TTM)

ARWR:

-$168.38M

ALNY:

$822.65M

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Return for Risk

ARWR vs. ALNY — Risk / Return Rank

Compare historical risk-adjusted metric ranks over the past 12 months.

ARWR
ARWR Risk / Return Rank: 9999
Overall Rank
ARWR Sharpe Ratio Rank: 100100
Sharpe Ratio Rank
ARWR Sortino Ratio Rank: 9999
Sortino Ratio Rank
ARWR Omega Ratio Rank: 9898
Omega Ratio Rank
ARWR Calmar Ratio Rank: 100100
Calmar Ratio Rank
ARWR Martin Ratio Rank: 100100
Martin Ratio Rank

ALNY
ALNY Risk / Return Rank: 66
Overall Rank
ALNY Sharpe Ratio Rank: 44
Sharpe Ratio Rank
ALNY Sortino Ratio Rank: 88
Sortino Ratio Rank
ALNY Omega Ratio Rank: 55
Omega Ratio Rank
ALNY Calmar Ratio Rank: 1212
Calmar Ratio Rank
ALNY Martin Ratio Rank: 33
Martin Ratio Rank
The rank (0–100) uses a weighted average of the Sharpe, Sortino, Omega, Calmar, and Martin percentile ranks for the trailing 12 months. Higher means stronger historical risk-adjusted performance within the peer group.

ARWR vs. ALNY - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Arrowhead Pharmaceuticals, Inc. (ARWR) and Alnylam Pharmaceuticals, Inc. (ALNY). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.


ARWRALNYDifference
Sharpe ratioReturn per unit of total volatility

+7.76

Sortino ratioReturn per unit of downside risk

+7.12

Omega ratioGain probability vs. loss probability

1.70

0.78

+0.92

Calmar ratioReturn relative to maximum drawdown

17.83

-0.82

+18.65

Martin ratioReturn relative to average drawdown

51.66

-1.68

+53.34

ARWR vs. ALNY - Sharpe Ratio Comparison

The current ARWR Sharpe Ratio is 6.69, which is higher than the ALNY Sharpe Ratio of -1.07. The chart below compares the historical Sharpe Ratios of ARWR and ALNY, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.


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Drawdowns

ARWR vs. ALNY - Drawdown Comparison

The maximum ARWR drawdown since its inception was -99.24%, which is greater than ALNY's maximum drawdown of -83.58%. Use the drawdown chart below to compare losses from any high point for ARWR and ALNY.


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Drawdown Indicators


ARWRALNYDifference

Max Drawdown

Largest peak-to-trough decline

-99.24%

-83.58%

-15.66%

Max Drawdown (1Y)

Largest decline over 1 year

-24.64%

-58.17%

+33.53%

Max Drawdown (3Y)

Largest decline over 3 years

-74.70%

-58.17%

-16.53%

Max Drawdown (5Y)

Largest decline over 5 years

-87.89%

-58.17%

-29.72%

Max Drawdown (10Y)

Largest decline over 10 years

-88.96%

-59.95%

-29.01%

Current Drawdown

Current decline from peak

-47.91%

-58.16%

+10.25%

Average Drawdown

Average peak-to-trough decline

-81.07%

-30.66%

-50.41%

Ulcer Index

Depth and duration of drawdowns from previous peaks

8.49%

28.31%

-19.82%

Volatility

ARWR vs. ALNY - Volatility Comparison

The current volatility for Arrowhead Pharmaceuticals, Inc. (ARWR) is 23.10%, while Alnylam Pharmaceuticals, Inc. (ALNY) has a volatility of 35.07%. This indicates that ARWR experiences smaller price fluctuations and is considered to be less risky than ALNY based on this measure. The chart below showcases a comparison of their rolling one-month volatility.


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Volatility by Period


ARWRALNYDifference

Volatility (1M)

Calculated over the trailing 1-month period

23.10%

35.07%

-11.97%

Volatility (6M)

Calculated over the trailing 6-month period

39.03%

41.89%

-2.86%

Volatility (1Y)

Calculated over the trailing 1-year period

65.63%

47.33%

+18.30%

Volatility (5Y)

Calculated over the trailing 5-year period, annualized

64.63%

50.53%

+14.10%

Volatility (10Y)

Calculated over the trailing 10-year period, annualized

74.38%

54.28%

+20.10%

Dividends

ARWR vs. ALNY - Dividend Comparison

Neither ARWR nor ALNY has paid dividends to shareholders.


Tickers have no history of dividend payments

Financials

ARWR vs. ALNY - Financials Comparison

This section allows you to compare key financial metrics between Arrowhead Pharmaceuticals, Inc. and Alnylam Pharmaceuticals, Inc.. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.


Quarterly
Annual

Total Revenue: Total amount of money received from sales and other business activities


Values in USD except per share items

Frequently Asked Questions


ARWR and ALNY have a correlation of 0.23, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

ALNY has higher volatility (35.07%) compared to ARWR (23.10%). In terms of maximum drawdown, ARWR dropped -99.24% vs ALNY's -83.58%.

ARWR currently has the higher Sharpe Ratio (6.69 vs -1.07), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.

Portfolio Optimizer

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