- ISIN
- US04280A1007
- CUSIP
- 04280A100
- Sector
- Healthcare
- Industry
- Biotechnology
- IPO Date
- Jun 16, 1993
Highlights
- Market Cap
- $11.68B
- Enterprise Value
- $12.33B
- EPS (TTM)
- -$2.16
- Total Revenue (TTM)
- $622.01M
- Gross Profit (TTM)
- $529.27M
- EBITDA (TTM)
- -$168.38M
- Year Range
- $14.30 - $84.55
- Target Price
- $81.22
- ROA (TTM)
- -13.27%
- ROE (TTM)
- -50.24%
Share Price Chart
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Performance
ARWR Performance Chart
Arrowhead Pharmaceuticals, Inc. (ARWR) is up 23.5% since the beginning of the year. At $82 per share, ARWR is trading 3.0% below its 52-week high of $85. Investors who bought $1,000 worth of ARWR shares 5 years ago would now be looking at an investment worth $931.
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Returns By Period
Arrowhead Pharmaceuticals, Inc. (ARWR) has returned 23.51% so far this year and 435.25% over the past 12 months. Looking at the last ten years, ARWR has achieved an annualized return of 31.09%, outperforming the S&P 500 Index benchmark, which averaged 13.88% per year.
Arrowhead Pharmaceuticals, Inc.
- 1D
- 0.22%
- 1M
- 9.41%
- YTD
- 23.51%
- 6M
- 18.84%
- 1Y
- 435.25%
- 3Y*
- 32.51%
- 5Y*
- -1.42%
- 10Y*
- 31.09%
Benchmark (S&P 500 Index)
- 1D
- -0.37%
- 1M
- -0.01%
- YTD
- 9.16%
- 6M
- 8.64%
- 1Y
- 25.22%
- 3Y*
- 19.78%
- 5Y*
- 11.99%
- 10Y*
- 13.88%
ARWR Monthly Returns History
Based on dividend-adjusted daily data since Jan 6, 1997, ARWR's average daily return is +0.42%, while the average monthly return is +4.42%. At this rate, an investment would double in approximately 1.3 years.
Historically, 44% of months were positive and 56% were negative. The best month was Jan 2004 with a return of +438.5%, while the worst month was Nov 2016 at -75.2%. The longest winning streak lasted 8 consecutive months, and the longest losing streak was 10 months.
On a daily basis, ARWR closed higher 36% of trading days. The best single day was May 30, 2002 with a return of +300.4%, while the worst single day was May 24, 2002 at -85.7%.
| Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec | Total | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2026 | 4.43% | -8.74% | -0.90% | 17.19% | 6.03% | 5.25% | 23.51% | ||||||
| 2025 | 5.74% | -4.88% | -32.63% | 9.03% | 15.69% | -1.68% | 0.00% | 39.43% | 56.56% | 22.91% | 24.32% | 25.98% | 253.14% |
| 2024 | 4.90% | -0.00% | -10.90% | -20.91% | 1.46% | 13.25% | 9.89% | -16.56% | -18.72% | -0.72% | 35.36% | -27.78% | -38.56% |
| 2023 | -13.73% | -7.69% | -21.36% | 39.41% | -2.82% | 3.63% | -3.20% | -19.93% | -2.79% | -8.49% | -13.79% | 44.34% | -24.56% |
| 2022 | -20.42% | -16.60% | 4.52% | -10.61% | -18.85% | 5.55% | 20.79% | -6.63% | -16.77% | 5.33% | -7.50% | 25.96% | -38.82% |
| 2021 | 0.57% | 3.23% | -16.76% | 9.73% | -0.22% | 14.08% | -16.34% | -3.13% | -6.99% | 2.23% | 9.76% | -5.35% | -13.59% |
Benchmark Metrics
Arrowhead Pharmaceuticals, Inc. has an annualized alpha of 165.26%, beta of 0.80, and R2 of 0.01 versus S&P 500 Index. Calculated based on daily prices since January 06, 1997.
- This stock participated in 143.29% of S&P 500 Index downside but only 111.82% of its upside - more exposed to losses than it benefited from rallies.
- R2 of 0.01 means this stock moves largely independently of S&P 500 Index - capture ratios reflect limited market correlation rather than active downside protection. Consider using a more representative benchmark.
- Alpha
- 165.26%
- Beta
- 0.80
- R²
- 0.01
- Upside Capture
- 111.82%
- Downside Capture
- 143.29%
Return for Risk
Risk / Return Rank
ARWR ranks 99 for risk / return — in the top 99% of stocks on our site. This means strong returns relative to risk — exactly what professional investors look for. Well-suited for investors who want to maximize return per unit of risk.
Return / Risk — by metrics
The table below present risk-adjusted performance metrics for Arrowhead Pharmaceuticals, Inc. (ARWR) and compare them to S&P 500 Index.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| ARWR | Benchmark | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | +4.69 | ||
| Sortino ratioReturn per unit of downside risk | +2.53 | ||
| Omega ratioGain probability vs. loss probability | 1.68 | 1.37 | +0.31 |
| Calmar ratioReturn relative to maximum drawdown | 17.81 | 2.78 | +15.02 |
| Martin ratioReturn relative to average drawdown | 49.05 | 12.44 | +36.61 |
Dividends
Dividend History
Drawdowns
Drawdowns Chart
The Drawdowns chart displays portfolio losses from any high point along the way. Drawdowns are calculated considering price movements and all distributions paid, if any.
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Worst Drawdowns
The table below displays the maximum drawdowns of the Arrowhead Pharmaceuticals, Inc.. A maximum drawdown is a measure of risk, indicating the largest reduction in portfolio value due to a series of losing trades.
The maximum drawdown for the Arrowhead Pharmaceuticals, Inc. was 99.24%, occurring on Dec 16, 2016. The portfolio has not yet recovered.
The current Arrowhead Pharmaceuticals, Inc. drawdown is 49.54%.
Related event | Drawdown | Fall | Recovery | Underwater |
|---|---|---|---|---|
2016 bear market2016 | -99.24%Dec 2016 | 16y 9mo | — | 26y 3moMar 2000 - now |
1997 bear market1997 | -86.35%Dec 1997 | 11mo 12d | 2y 2mo | 3y 1moJan 1997 - Mar 2000 |
Drawdown Indicators
| ARWR | Benchmark | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -99.24% | -56.78% | -42.46% |
Max Drawdown (1Y)Largest decline over 1 year | -24.64% | -9.10% | -15.54% |
Max Drawdown (3Y)Largest decline over 3 years | -74.70% | -18.90% | -55.80% |
Max Drawdown (5Y)Largest decline over 5 years | -88.94% | -25.43% | -63.51% |
Max Drawdown (10Y)Largest decline over 10 years | -88.96% | -33.92% | -55.04% |
Current DrawdownCurrent decline from peak | -49.54% | -1.80% | -47.74% |
Average DrawdownAverage peak-to-trough decline | -81.19% | -10.71% | -70.48% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 8.93% | 2.03% | +6.90% |
Volatility
Volatility Chart
The chart below shows the rolling one-month volatility.
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Financials
Financial Performance
The chart below illustrates the trends in the financial health of Arrowhead Pharmaceuticals, Inc. over time, highlighting three key metrics: Total Revenue, Earnings Before Interest and Taxes (EBIT), and Net Income.
Valuation
The Valuation section provides an overview of how Arrowhead Pharmaceuticals, Inc. is priced in the market compared to other companies in the Biotechnology industry. It includes key financial ratios that help investors assess whether the stock is undervalued or overvalued.
PS Ratio
This chart shows the Price-to-Sales (P/S) ratio for ARWR relative to other companies in the Biotechnology industry. Currently, ARWR has a P/S ratio of 18.4. This P/S ratio falls within the average range for the industry, suggesting the stock is fairly valued based on its revenue.
PB Ratio
The chart illustrates the Price-to-Book (P/B) ratio for ARWR in comparison with other companies in the Biotechnology industry. Currently, ARWR has a P/B value of 19.5. This P/B ratio is higher than most companies in the industry. It may suggest the stock is overvalued or that investors expect the company to generate high returns on its assets.
Income Statement
| TTM | |
|---|---|
Revenue | — |
Total Revenue | — |
Cost Of Revenue | — |
Gross Profit | — |
Operating Expenses | — |
Selling, General & Admin Expenses | — |
R&D Expenses | — |
Depreciation And Amortization | — |
Total Operating Expenses | — |
Income | — |
Income Before Tax | — |
Operating Income | — |
EBITDA | — |
EBIT | — |
Earnings From Continuing Operations | — |
Net Income | — |
Income Tax Expense | — |
Other Non-Operating Income (Expenses) | — |
Extraordinary Items | — |
Discontinued Operations | — |
Effect Of Accounting Charges | — |
Non Recurring | — |
Minority Interest | — |
Other Items | — |
Interest Income | — |
Interest Expense | — |
Net Interest Income | — |
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