ARWR vs. AXTI

Last updated Jun 4, 2026

ARWR (Arrowhead Pharmaceuticals, Inc.) and AXTI (AXT, Inc.) are both stocks. ARWR operates in Biotechnology (Healthcare), while AXTI operates in Semiconductor Equipment & Materials (Technology). Over the past 10 years, ARWR returned 28.05%/yr vs 40.50%/yr for AXTI. At a 0.14 correlation, their price movements are largely independent.

Performance

ARWR vs. AXTI - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Arrowhead Pharmaceuticals, Inc. (ARWR) and AXT, Inc. (AXTI). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, ARWR achieves a 9.28% return, which is significantly lower than AXTI's 552.60% return. Over the past 10 years, ARWR has underperformed AXTI with an annualized return of 28.05%, while AXTI has yielded a comparatively higher 40.50% annualized return.

ARWR

• 1D: 2.44%
• 1M: -5.03%
• YTD: 9.28%
• 6M: 11.49%
• 1Y: 336.79%
• 3Y*: 26.25%
• 5Y*: -0.96%
• 10Y*: 28.05%

AXTI

• 1D: -3.74%
• 1M: 0.66%
• YTD: 552.60%
• 6M: 829.44%
• 1Y: 6,085.51%
• 3Y*: 212.99%
• 5Y*: 58.76%
• 10Y*: 40.50%

*Multi-year figures are annualized to reflect compound growth (CAGR)

ARWR vs. AXTI - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018	2017
ARWR Arrowhead Pharmaceuticals, Inc.	9.28%	253.14%	-38.56%	-24.56%	-38.82%	-13.59%	20.97%	410.71%	237.50%	137.42%
AXTI AXT, Inc.	552.60%	653.46%	-9.58%	-45.21%	-50.28%	-7.94%	120.00%	-0.00%	-50.00%	81.25%

Correlation

The correlation between ARWR and AXTI is 0.13, which is low. Their price movements are largely independent, making them effective diversification partners.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.13
Correlation (3Y) Calculated over the trailing 3-year period	0.22
Correlation (5Y) Calculated over the trailing 5-year period	0.28
Correlation (10Y) Calculated over the trailing 10-year period	0.26
Correlation (All Time) Calculated using the full available price history since May 22, 1998	0.14

The correlation between ARWR and AXTI shifts across timeframes, from 0.13 (1 year) to 0.28 (5 years), reflecting how their relationship changes across market environments.

Fundamentals

Market Cap ARWR : $10.33B AXTI : $5.69B
EPS ARWR : -$2.16 AXTI : -$0.30
PS Ratio ARWR : 16.27 AXTI : 51.59
PB Ratio ARWR : 17.25 AXTI : 20.97
Total Revenue (TTM) ARWR : $622.01M AXTI : $95.89M
Gross Profit (TTM) ARWR : $529.27M AXTI : $20.46M
EBITDA (TTM) ARWR : -$168.38M AXTI : -$7.63M

Return for Risk

ARWR vs. AXTI — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

ARWR

ARWR Risk / Return Rank: 98
ARWR Sharpe Ratio Rank: 99
ARWR Sortino Ratio Rank: 97
ARWR Omega Ratio Rank: 95
ARWR Calmar Ratio Rank: 98
ARWR Martin Ratio Rank: 98

AXTI

AXTI Risk / Return Rank: 99
AXTI Sharpe Ratio Rank: 100
AXTI Sortino Ratio Rank: 99
AXTI Omega Ratio Rank: 98
AXTI Calmar Ratio Rank: 100
AXTI Martin Ratio Rank: 100

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

ARWR vs. AXTI - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Arrowhead Pharmaceuticals, Inc. (ARWR) and AXT, Inc. (AXTI). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	ARWR	AXTI	Difference
Sharpe ratio Return per unit of total volatility	5.22	45.71	-40.49
Sortino ratio Return per unit of downside risk	4.69	6.96	-2.27
Omega ratio Gain probability vs. loss probability	1.59	1.87	-0.27
Calmar ratio Return relative to maximum drawdown	13.77	160.12	-146.35
Martin ratio Return relative to average drawdown	37.74	490.82	-453.08
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

ARWR vs. AXTI - Sharpe Ratio Comparison

The current ARWR Sharpe Ratio is 5.22, which is lower than the AXTI Sharpe Ratio of 45.71. The chart below compares the historical Sharpe Ratios of ARWR and AXTI, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Sharpe Ratios by Period

	ARWR	AXTI	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	5.22	45.71	-40.49
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	-0.01	0.62	-0.63
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	0.38	0.49	-0.11
Sharpe Ratio (All Time) Calculated using the full available price history	-0.01	0.11	-0.12

Drawdowns

ARWR vs. AXTI - Drawdown Comparison

The maximum ARWR drawdown since its inception was -99.24%, roughly equal to the maximum AXTI drawdown of -98.57%. Use the drawdown chart below to compare losses from any high point for ARWR and AXTI.

Drawdown Indicators

	ARWR	AXTI	Difference
Max Drawdown Largest peak-to-trough decline	-99.24%	-98.57%	-0.67%
Max Drawdown (1Y) Largest decline over 1 year	-24.64%	-38.65%	+14.01%
Max Drawdown (3Y) Largest decline over 3 years	-74.70%	-78.52%	+3.82%
Max Drawdown (5Y) Largest decline over 5 years	-88.94%	-90.57%	+1.63%
Max Drawdown (10Y) Largest decline over 10 years	-88.96%	-92.45%	+3.49%
Current Drawdown Current decline from peak	-55.35%	-24.23%	-31.12%
Average Drawdown Average peak-to-trough decline	-81.24%	-82.33%	+1.09%
Ulcer Index Depth and duration of drawdowns from previous peaks	8.97%	12.58%	-3.61%

Volatility

ARWR vs. AXTI - Volatility Comparison

The current volatility for Arrowhead Pharmaceuticals, Inc. (ARWR) is 17.17%, while AXT, Inc. (AXTI) has a volatility of 37.30%. This indicates that ARWR experiences smaller price fluctuations and is considered to be less risky than AXTI based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	ARWR	AXTI	Difference
Volatility (1M) Calculated over the trailing 1-month period	17.17%	37.30%	-20.13%
Volatility (6M) Calculated over the trailing 6-month period	39.41%	112.04%	-72.63%
Volatility (1Y) Calculated over the trailing 1-year period	65.03%	135.60%	-70.57%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	65.03%	95.88%	-30.85%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	74.14%	82.31%	-8.17%

Dividends

ARWR vs. AXTI - Dividend Comparison

Neither ARWR nor AXTI has paid dividends to shareholders.

Tickers have no history of dividend payments

Financials

Frequently Asked Questions

Can I hold both ARWR and AXTI in my portfolio?

ARWR and AXTI have a correlation of 0.13, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, ARWR or AXTI?

AXTI has higher volatility (37.30%) compared to ARWR (17.17%). In terms of maximum drawdown, ARWR dropped -99.24% vs AXTI's -98.57%.

Which has better risk-adjusted returns?

AXTI currently has the higher Sharpe Ratio (45.71 vs 5.22), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.