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ALNY vs. ABBV
Performance
Return for Risk
Drawdowns
Volatility
Dividends
Financials

Performance

ALNY vs. ABBV - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Alnylam Pharmaceuticals, Inc. (ALNY) and AbbVie Inc. (ABBV). The values are adjusted to include any dividend payments, if applicable.

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Returns By Period

In the year-to-date period, ALNY achieves a -48.32% return, which is significantly lower than ABBV's 12.42% return. Over the past 10 years, ALNY has underperformed ABBV with an annualized return of 11.28%, while ABBV has yielded a comparatively higher 18.94% annualized return.


ALNY

1D
0.02%
1M
-34.29%
6M
-39.21%
YTD
-48.32%
1Y
-48.85%
3Y*
2.82%
5Y*
2.81%
10Y*
11.28%
ALL TIME*
17.20%

ABBV

1D
-2.51%
1M
-3.20%
6M
14.27%
YTD
12.42%
1Y
32.53%
3Y*
23.28%
5Y*
20.99%
10Y*
18.94%
ALL TIME*
20.35%
*Multi-year figures are annualized to reflect compound growth (CAGR)

Liquidity Comparison


PositionAvg. Volume Value (2W)Avg. Volume Value (1M)Avg. Volume Value (3M)
$1.40B$1.53B$1.60B
$567.18M$557.43M$409.61M

ALNY vs. ABBV - Yearly Performance Comparison


2026 (YTD)202520242023202220212020201920182017
ALNY
Alnylam Pharmaceuticals, Inc.
-48.32%68.99%22.94%-19.46%40.14%30.48%12.85%57.96%-42.61%239.34%
ABBV
AbbVie Inc.
12.42%33.08%18.86%-0.23%24.01%32.43%27.72%1.47%-0.96%60.07%

Correlation

The correlation between ALNY and ABBV is 0.25, which is low. Their historical price movements had little consistent relationship.


Correlation
Correlation (1Y)
Focuses on recent behavior, but can change the most.

0.25

Correlation (3Y)
Balances recent behavior with more history.

0.18

Correlation (5Y)
Shows whether the relationship held over a longer period.

0.19

Correlation (10Y)
Provides a long-term view across more market conditions.

0.26

Correlation (All Time)
Calculated using the full available price history since Jan 2, 2013

0.30

The correlation between ALNY and ABBV shifts across timeframes, from 0.18 (3 years) to 0.30 (all time), reflecting how their relationship changes across market environments.

Fundamentals

Market Cap

ALNY:

$27.44B

ABBV:

$443.24B

EPS

ALNY:

$5.88

ABBV:

$2.05

PE Ratio

ALNY:

34.98

ABBV:

122.29

PS Ratio

ALNY:

5.88

ABBV:

7.08

PB Ratio

ALNY:

20.98

ABBV:

16.19

Total Revenue (TTM)

ALNY:

$4.80B

ABBV:

$62.82B

Gross Profit (TTM)

ALNY:

$1.88B

ABBV:

$46.15B

EBITDA (TTM)

ALNY:

$822.65M

ABBV:

$17.96B

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Return for Risk

ALNY vs. ABBV — Risk / Return Rank

Compare historical risk-adjusted metric ranks over the past 12 months.

ALNY
ALNY Risk / Return Rank: 66
Overall Rank
ALNY Sharpe Ratio Rank: 44
Sharpe Ratio Rank
ALNY Sortino Ratio Rank: 88
Sortino Ratio Rank
ALNY Omega Ratio Rank: 55
Omega Ratio Rank
ALNY Calmar Ratio Rank: 1212
Calmar Ratio Rank
ALNY Martin Ratio Rank: 33
Martin Ratio Rank

ABBV
ABBV Risk / Return Rank: 8181
Overall Rank
ABBV Sharpe Ratio Rank: 8484
Sharpe Ratio Rank
ABBV Sortino Ratio Rank: 8282
Sortino Ratio Rank
ABBV Omega Ratio Rank: 8080
Omega Ratio Rank
ABBV Calmar Ratio Rank: 8080
Calmar Ratio Rank
ABBV Martin Ratio Rank: 7979
Martin Ratio Rank
The rank (0–100) uses a weighted average of the Sharpe, Sortino, Omega, Calmar, and Martin percentile ranks for the trailing 12 months. Higher means stronger historical risk-adjusted performance within the peer group.

ALNY vs. ABBV - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Alnylam Pharmaceuticals, Inc. (ALNY) and AbbVie Inc. (ABBV). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.


ALNYABBVDifference
Sharpe ratioReturn per unit of total volatility

-2.49

Sortino ratioReturn per unit of downside risk

-3.52

Omega ratioGain probability vs. loss probability

0.78

1.26

-0.48

Calmar ratioReturn relative to maximum drawdown

-0.82

2.14

-2.96

Martin ratioReturn relative to average drawdown

-1.68

4.73

-6.42

ALNY vs. ABBV - Sharpe Ratio Comparison

The current ALNY Sharpe Ratio is -1.07, which is lower than the ABBV Sharpe Ratio of 1.42. The chart below compares the historical Sharpe Ratios of ALNY and ABBV, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.


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Drawdowns

ALNY vs. ABBV - Drawdown Comparison

The maximum ALNY drawdown since its inception was -83.58%, which is greater than ABBV's maximum drawdown of -45.09%. Use the drawdown chart below to compare losses from any high point for ALNY and ABBV.


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Drawdown Indicators


ALNYABBVDifference

Max Drawdown

Largest peak-to-trough decline

-83.58%

-45.09%

-38.49%

Max Drawdown (1Y)

Largest decline over 1 year

-58.17%

-17.32%

-40.85%

Max Drawdown (3Y)

Largest decline over 3 years

-58.17%

-20.74%

-37.43%

Max Drawdown (5Y)

Largest decline over 5 years

-58.17%

-21.92%

-36.25%

Max Drawdown (10Y)

Largest decline over 10 years

-59.95%

-45.09%

-14.86%

Current Drawdown

Current decline from peak

-58.16%

-4.69%

-53.47%

Average Drawdown

Average peak-to-trough decline

-30.66%

-10.64%

-20.02%

Ulcer Index

Depth and duration of drawdowns from previous peaks

28.31%

7.81%

+20.50%

Volatility

ALNY vs. ABBV - Volatility Comparison

Alnylam Pharmaceuticals, Inc. (ALNY) has a higher volatility of 35.07% compared to AbbVie Inc. (ABBV) at 8.35%. This indicates that ALNY's price experiences larger fluctuations and is considered to be riskier than ABBV based on this measure. The chart below showcases a comparison of their rolling one-month volatility.


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Volatility by Period


ALNYABBVDifference

Volatility (1M)

Calculated over the trailing 1-month period

35.07%

8.35%

+26.72%

Volatility (6M)

Calculated over the trailing 6-month period

41.89%

19.56%

+22.33%

Volatility (1Y)

Calculated over the trailing 1-year period

47.33%

26.14%

+21.19%

Volatility (5Y)

Calculated over the trailing 5-year period, annualized

50.53%

23.46%

+27.07%

Volatility (10Y)

Calculated over the trailing 10-year period, annualized

54.28%

25.92%

+28.36%

Dividends

ALNY vs. ABBV - Dividend Comparison

ALNY has not paid dividends to shareholders, while ABBV's dividend yield for the trailing twelve months is around 2.72%.


PositionTTM20252024202320222021202020192018201720162015
ABBV
AbbVie Inc.
2.72%2.87%3.49%3.82%3.49%3.84%4.41%4.83%3.89%2.65%3.64%3.41%
ALNY
Alnylam Pharmaceuticals, Inc.
0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%

Financials

ALNY vs. ABBV - Financials Comparison

This section allows you to compare key financial metrics between Alnylam Pharmaceuticals, Inc. and AbbVie Inc.. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.


Quarterly
Annual

Total Revenue: Total amount of money received from sales and other business activities


Values in USD except per share items

ALNY vs. ABBV - Profitability Comparison

The chart below illustrates the profitability comparison between Alnylam Pharmaceuticals, Inc. and AbbVie Inc. over time, highlighting three key metrics: Gross Profit Margin, Operating Margin, and Net Profit Margin.

Gross Margin
Operating Margin
Net Margin
Quarterly
Annual

ALNY - Gross Margin

Gross margin is calculated as gross profit divided by revenue. For the three months ending on Aug 2026, Alnylam Pharmaceuticals, Inc. reported a gross profit of -956.05M and revenue of 1.29B. Therefore, the gross margin over that period was -74.1%.

ABBV - Gross Margin

Gross margin is calculated as gross profit divided by revenue. For the three months ending on Aug 2026, AbbVie Inc. reported a gross profit of 12.53B and revenue of 15.00B. Therefore, the gross margin over that period was 83.5%.

ALNY - Operating Margin

Operating margin is calculated as operating income divided by revenue. For the three months ending on Aug 2026, Alnylam Pharmaceuticals, Inc. reported an operating income of 231.44M and revenue of 1.29B, resulting in an operating margin of 17.9%.

ABBV - Operating Margin

Operating margin is calculated as operating income divided by revenue. For the three months ending on Aug 2026, AbbVie Inc. reported an operating income of 4.73B and revenue of 15.00B, resulting in an operating margin of 31.6%.

ALNY - Net Margin

Net margin is calculated as net income divided by revenue. For the three months ending on Aug 2026, Alnylam Pharmaceuticals, Inc. reported a net income of 164.49M and revenue of 1.29B, resulting in a net margin of 12.7%.

ABBV - Net Margin

Net margin is calculated as net income divided by revenue. For the three months ending on Aug 2026, AbbVie Inc. reported a net income of 699.00M and revenue of 15.00B, resulting in a net margin of 4.7%.


Frequently Asked Questions


ALNY and ABBV have a correlation of 0.25, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

ALNY has higher volatility (35.07%) compared to ABBV (8.35%). In terms of maximum drawdown, ALNY dropped -83.58% vs ABBV's -45.09%.

ABBV currently has the higher Sharpe Ratio (1.42 vs -1.07), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.

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