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ARWR vs. XBI
Performance
Risk-Adjusted Performance
Dividends
Drawdowns
Volatility

Correlation

The correlation between ARWR and XBI is 0.32, which is considered to be low. This implies their price changes are not closely related. A low correlation is generally favorable for portfolio diversification, as it helps to reduce overall risk by spreading it across multiple assets with different performance patterns.


Performance

ARWR vs. XBI - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Arrowhead Pharmaceuticals, Inc. (ARWR) and SPDR S&P Biotech ETF (XBI). The values are adjusted to include any dividend payments, if applicable.

-100.00%0.00%100.00%200.00%300.00%400.00%500.00%600.00%December2025FebruaryMarchAprilMay
-73.13%
390.10%
ARWR
XBI

Key characteristics

Sharpe Ratio

ARWR:

-0.71

XBI:

-0.51

Sortino Ratio

ARWR:

-0.95

XBI:

-0.62

Omega Ratio

ARWR:

0.89

XBI:

0.92

Calmar Ratio

ARWR:

-0.49

XBI:

-0.26

Martin Ratio

ARWR:

-1.45

XBI:

-1.30

Ulcer Index

ARWR:

32.95%

XBI:

11.84%

Daily Std Dev

ARWR:

66.49%

XBI:

27.45%

Max Drawdown

ARWR:

-99.83%

XBI:

-63.89%

Current Drawdown

ARWR:

-98.22%

XBI:

-56.01%

Returns By Period

In the year-to-date period, ARWR achieves a -30.69% return, which is significantly lower than XBI's -15.17% return. Over the past 10 years, ARWR has outperformed XBI with an annualized return of 7.61%, while XBI has yielded a comparatively lower 0.30% annualized return.


ARWR

YTD

-30.69%

1M

10.42%

6M

-40.48%

1Y

-47.29%

5Y*

-17.56%

10Y*

7.61%

XBI

YTD

-15.17%

1M

2.02%

6M

-26.67%

1Y

-14.02%

5Y*

-5.10%

10Y*

0.30%

*Annualized

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Risk-Adjusted Performance

ARWR vs. XBI — Risk-Adjusted Performance Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

ARWR
The Risk-Adjusted Performance Rank of ARWR is 1515
Overall Rank
The Sharpe Ratio Rank of ARWR is 1414
Sharpe Ratio Rank
The Sortino Ratio Rank of ARWR is 1414
Sortino Ratio Rank
The Omega Ratio Rank of ARWR is 1616
Omega Ratio Rank
The Calmar Ratio Rank of ARWR is 2121
Calmar Ratio Rank
The Martin Ratio Rank of ARWR is 88
Martin Ratio Rank

XBI
The Risk-Adjusted Performance Rank of XBI is 55
Overall Rank
The Sharpe Ratio Rank of XBI is 55
Sharpe Ratio Rank
The Sortino Ratio Rank of XBI is 44
Sortino Ratio Rank
The Omega Ratio Rank of XBI is 55
Omega Ratio Rank
The Calmar Ratio Rank of XBI is 77
Calmar Ratio Rank
The Martin Ratio Rank of XBI is 33
Martin Ratio Rank
The risk-adjusted ranks indicate the investment's position relative to the market. A rank closer to 100 signifies top-performing investments, while a rank closer to 0 might suggest underperformance, based on the selected ratio. The values are calculated based on the past 12 months of returns.

ARWR vs. XBI - Risk-Adjusted Performance Comparison

This table presents a comparison of risk-adjusted performance metrics for Arrowhead Pharmaceuticals, Inc. (ARWR) and SPDR S&P Biotech ETF (XBI). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.


The current ARWR Sharpe Ratio is -0.71, which is lower than the XBI Sharpe Ratio of -0.51. The chart below compares the historical Sharpe Ratios of ARWR and XBI, offering insights into how both investments have performed under varying market conditions. These values are calculated using daily returns over the previous 12 months.


Rolling 12-month Sharpe Ratio-1.00-0.500.000.501.001.502.002.50December2025FebruaryMarchAprilMay
-0.71
-0.51
ARWR
XBI

Dividends

ARWR vs. XBI - Dividend Comparison

ARWR has not paid dividends to shareholders, while XBI's dividend yield for the trailing twelve months is around 0.18%.


TTM20242023202220212020201920182017201620152014
ARWR
Arrowhead Pharmaceuticals, Inc.
0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%
XBI
SPDR S&P Biotech ETF
0.18%0.15%0.02%0.00%0.04%0.20%0.00%0.28%0.24%0.26%0.61%1.07%

Drawdowns

ARWR vs. XBI - Drawdown Comparison

The maximum ARWR drawdown since its inception was -99.83%, which is greater than XBI's maximum drawdown of -63.89%. Use the drawdown chart below to compare losses from any high point for ARWR and XBI. For additional features, visit the drawdowns tool.


-90.00%-80.00%-70.00%-60.00%-50.00%-40.00%December2025FebruaryMarchAprilMay
-85.60%
-56.01%
ARWR
XBI

Volatility

ARWR vs. XBI - Volatility Comparison

Arrowhead Pharmaceuticals, Inc. (ARWR) has a higher volatility of 21.38% compared to SPDR S&P Biotech ETF (XBI) at 11.38%. This indicates that ARWR's price experiences larger fluctuations and is considered to be riskier than XBI based on this measure. The chart below showcases a comparison of their rolling one-month volatility.


5.00%10.00%15.00%20.00%25.00%30.00%December2025FebruaryMarchAprilMay
21.38%
11.38%
ARWR
XBI