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ALNY vs. SPY
Performance
Risk-Adjusted Performance
Dividends
Drawdowns
Volatility

Correlation

The correlation between ALNY and SPY is 0.42, which is considered to be moderate. This suggests that the two assets have some degree of positive relationship in their price movements. Moderate correlation can be acceptable for portfolio diversification, offering a balance between risk and potential returns.


Performance

ALNY vs. SPY - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Alnylam Pharmaceuticals, Inc. (ALNY) and SPDR S&P 500 ETF (SPY). The values are adjusted to include any dividend payments, if applicable.

1,000.00%2,000.00%3,000.00%4,000.00%5,000.00%December2025FebruaryMarchAprilMay
4,198.67%
643.11%
ALNY
SPY

Key characteristics

Sharpe Ratio

ALNY:

1.27

SPY:

0.54

Sortino Ratio

ALNY:

2.42

SPY:

0.90

Omega Ratio

ALNY:

1.31

SPY:

1.13

Calmar Ratio

ALNY:

1.81

SPY:

0.57

Martin Ratio

ALNY:

5.78

SPY:

2.24

Ulcer Index

ALNY:

12.26%

SPY:

4.82%

Daily Std Dev

ALNY:

55.42%

SPY:

20.02%

Max Drawdown

ALNY:

-83.58%

SPY:

-55.19%

Current Drawdown

ALNY:

-14.04%

SPY:

-7.53%

Returns By Period

In the year-to-date period, ALNY achieves a 9.79% return, which is significantly higher than SPY's -3.30% return. Over the past 10 years, ALNY has underperformed SPY with an annualized return of 8.59%, while SPY has yielded a comparatively higher 12.33% annualized return.


ALNY

YTD

9.79%

1M

15.17%

6M

-5.10%

1Y

69.64%

5Y*

13.72%

10Y*

8.59%

SPY

YTD

-3.30%

1M

13.81%

6M

-4.52%

1Y

10.65%

5Y*

15.81%

10Y*

12.33%

*Annualized

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Risk-Adjusted Performance

ALNY vs. SPY — Risk-Adjusted Performance Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

ALNY
The Risk-Adjusted Performance Rank of ALNY is 9090
Overall Rank
The Sharpe Ratio Rank of ALNY is 8888
Sharpe Ratio Rank
The Sortino Ratio Rank of ALNY is 9090
Sortino Ratio Rank
The Omega Ratio Rank of ALNY is 8989
Omega Ratio Rank
The Calmar Ratio Rank of ALNY is 9292
Calmar Ratio Rank
The Martin Ratio Rank of ALNY is 8989
Martin Ratio Rank

SPY
The Risk-Adjusted Performance Rank of SPY is 6363
Overall Rank
The Sharpe Ratio Rank of SPY is 5959
Sharpe Ratio Rank
The Sortino Ratio Rank of SPY is 6161
Sortino Ratio Rank
The Omega Ratio Rank of SPY is 6464
Omega Ratio Rank
The Calmar Ratio Rank of SPY is 6767
Calmar Ratio Rank
The Martin Ratio Rank of SPY is 6464
Martin Ratio Rank
The risk-adjusted ranks indicate the investment's position relative to the market. A rank closer to 100 signifies top-performing investments, while a rank closer to 0 might suggest underperformance, based on the selected ratio. The values are calculated based on the past 12 months of returns.

ALNY vs. SPY - Risk-Adjusted Performance Comparison

This table presents a comparison of risk-adjusted performance metrics for Alnylam Pharmaceuticals, Inc. (ALNY) and SPDR S&P 500 ETF (SPY). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.


The current ALNY Sharpe Ratio is 1.27, which is higher than the SPY Sharpe Ratio of 0.54. The chart below compares the historical Sharpe Ratios of ALNY and SPY, offering insights into how both investments have performed under varying market conditions. These values are calculated using daily returns over the previous 12 months.


Rolling 12-month Sharpe Ratio0.001.002.003.00December2025FebruaryMarchAprilMay
1.27
0.54
ALNY
SPY

Dividends

ALNY vs. SPY - Dividend Comparison

ALNY has not paid dividends to shareholders, while SPY's dividend yield for the trailing twelve months is around 1.27%.


TTM20242023202220212020201920182017201620152014
ALNY
Alnylam Pharmaceuticals, Inc.
0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%
SPY
SPDR S&P 500 ETF
1.27%1.21%1.40%1.65%1.20%1.52%1.75%2.04%1.80%2.03%2.06%1.87%

Drawdowns

ALNY vs. SPY - Drawdown Comparison

The maximum ALNY drawdown since its inception was -83.58%, which is greater than SPY's maximum drawdown of -55.19%. Use the drawdown chart below to compare losses from any high point for ALNY and SPY. For additional features, visit the drawdowns tool.


-25.00%-20.00%-15.00%-10.00%-5.00%0.00%December2025FebruaryMarchAprilMay
-14.04%
-7.53%
ALNY
SPY

Volatility

ALNY vs. SPY - Volatility Comparison

Alnylam Pharmaceuticals, Inc. (ALNY) has a higher volatility of 17.04% compared to SPDR S&P 500 ETF (SPY) at 12.36%. This indicates that ALNY's price experiences larger fluctuations and is considered to be riskier than SPY based on this measure. The chart below showcases a comparison of their rolling one-month volatility.


0.00%5.00%10.00%15.00%20.00%December2025FebruaryMarchAprilMay
17.04%
12.36%
ALNY
SPY