ARWR vs. ACLLY

Last updated Aug 1, 2026

ARWR (Arrowhead Pharmaceuticals, Inc.) and ACLLY (Accelleron Industries AG ADR) are both stocks. ARWR operates in Biotechnology (Healthcare), while ACLLY operates in Aerospace & Defense (Industrials). Over the past 3 years, ARWR returned 35.96%/yr vs 55.67%/yr for ACLLY. Their 0.11 correlation means their historical movements had little consistent relationship.

Performance

ARWR vs. ACLLY - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Arrowhead Pharmaceuticals, Inc. (ARWR) and Accelleron Industries AG ADR (ACLLY). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, ARWR achieves a 27.50% return, which is significantly higher than ACLLY's 19.06% return.

ARWR

• 1D: -3.06%
• 1M: 0.79%
• 6M: 22.10%
• YTD: 27.50%
• 1Y: 431.39%
• 3Y*: 35.96%
• 5Y*: 4.09%
• 10Y*: 30.88%
• ALL TIME*: -0.69%

ACLLY

• 1D: -0.60%
• 1M: -9.62%
• 6M: -3.20%
• YTD: 19.06%
• 1Y: 1.27%
• 3Y*: 55.67%
• 5Y*: —
• 10Y*: —
• ALL TIME*: 53.76%

*Multi-year figures are annualized to reflect compound growth (CAGR)

Liquidity Comparison

Position	Avg. Volume Value (2W)	Avg. Volume Value (1M)	Avg. Volume Value (3M)
ACLLY Accelleron Industries AG ADR	$85.27K	$75.65K	$96.85K
ARWR Arrowhead Pharmaceuticals, Inc.	$205.45M	$188.79M	$175.31M

ARWR vs. ACLLY - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022
ARWR Arrowhead Pharmaceuticals, Inc.	27.50%	253.14%	-38.56%	-24.56%	20.21%
ACLLY Accelleron Industries AG ADR	19.06%	56.70%	69.48%	60.55%	2.00%

Correlation

The correlation between ARWR and ACLLY is 0.17, which is low. Their historical price movements had little consistent relationship.

	Correlation
Correlation (1Y) Focuses on recent behavior, but can change the most.	0.17
Correlation (3Y) Balances recent behavior with more history.	0.11
Correlation (All Time) Calculated using the full available price history since Oct 4, 2022	0.11

Fundamentals

Market Cap ARWR : $11.92B ACLLY : $8.55B
EPS ARWR : -$2.16 ACLLY : $4.29
PS Ratio ARWR : 19.00 ACLLY : 3.74
PB Ratio ARWR : 20.13 ACLLY : 17.92
Total Revenue (TTM) ARWR : $622.01M ACLLY : $2.28B
Gross Profit (TTM) ARWR : $529.27M ACLLY : $1.02B
EBITDA (TTM) ARWR : -$168.38M ACLLY : $569.11M

Return for Risk

ARWR vs. ACLLY — Risk / Return Rank

Compare historical risk-adjusted metric ranks over the past 12 months.

ARWR

ARWR Risk / Return Rank: 99
ARWR Sharpe Ratio Rank: 100
ARWR Sortino Ratio Rank: 99
ARWR Omega Ratio Rank: 98
ARWR Calmar Ratio Rank: 100
ARWR Martin Ratio Rank: 100

ACLLY

ACLLY Risk / Return Rank: 44
ACLLY Sharpe Ratio Rank: 46
ACLLY Sortino Ratio Rank: 41
ACLLY Omega Ratio Rank: 40
ACLLY Calmar Ratio Rank: 46
ACLLY Martin Ratio Rank: 46

The rank (0–100) uses a weighted average of the Sharpe, Sortino, Omega, Calmar, and Martin percentile ranks for the trailing 12 months. Higher means stronger historical risk-adjusted performance within the peer group.

ARWR vs. ACLLY - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Arrowhead Pharmaceuticals, Inc. (ARWR) and Accelleron Industries AG ADR (ACLLY). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.

	ARWR	ACLLY	Difference
Sharpe ratio: Return per unit of total volatility	6.69	0.04	+6.66
Sortino ratio: Return per unit of downside risk	5.72	0.31	+5.42
Omega ratio: Gain probability vs. loss probability	1.70	1.04	+0.66
Calmar ratio: Return relative to maximum drawdown	17.83	0.05	+17.78
Martin ratio: Return relative to average drawdown	51.66	0.11	+51.55

ARWR vs. ACLLY - Sharpe Ratio Comparison

The current ARWR Sharpe Ratio is 6.69, which is higher than the ACLLY Sharpe Ratio of 0.04. The chart below compares the historical Sharpe Ratios of ARWR and ACLLY, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Drawdowns

ARWR vs. ACLLY - Drawdown Comparison

The maximum ARWR drawdown since its inception was -99.24%, which is greater than ACLLY's maximum drawdown of -30.00%. Use the drawdown chart below to compare losses from any high point for ARWR and ACLLY.

Drawdown Indicators

	ARWR	ACLLY	Difference
Max Drawdown Largest peak-to-trough decline	-99.24%	-30.00%	-69.24%
Max Drawdown (1Y) Largest decline over 1 year	-24.64%	-24.73%	+0.09%
Max Drawdown (3Y) Largest decline over 3 years	-74.70%	-28.69%	-46.01%
Max Drawdown (5Y) Largest decline over 5 years	-87.89%	—	—
Max Drawdown (10Y) Largest decline over 10 years	-88.96%	—	—
Current Drawdown Current decline from peak	-47.91%	-20.76%	-27.15%
Average Drawdown Average peak-to-trough decline	-81.07%	-6.16%	-74.91%
Ulcer Index Depth and duration of drawdowns from previous peaks	8.49%	11.84%	-3.35%

Volatility

ARWR vs. ACLLY - Volatility Comparison

Arrowhead Pharmaceuticals, Inc. (ARWR) has a higher volatility of 23.10% compared to Accelleron Industries AG ADR (ACLLY) at 11.69%. This indicates that ARWR's price experiences larger fluctuations and is considered to be riskier than ACLLY based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	ARWR	ACLLY	Difference
Volatility (1M) Calculated over the trailing 1-month period	23.10%	11.69%	+11.41%
Volatility (6M) Calculated over the trailing 6-month period	39.03%	28.54%	+10.49%
Volatility (1Y) Calculated over the trailing 1-year period	65.63%	33.72%	+31.91%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	64.63%	41.03%	+23.60%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	74.38%	41.03%	+33.35%

Dividends

ARWR vs. ACLLY - Dividend Comparison

ARWR has not paid dividends to shareholders, while ACLLY's dividend yield for the trailing twelve months is around 2.06%.

Position	TTM	2025	2024	2023
ACLLY Accelleron Industries AG ADR	2.06%	1.94%	2.95%	4.04%
ARWR Arrowhead Pharmaceuticals, Inc.	0.00%	0.00%	0.00%	0.00%

Financials

Frequently Asked Questions

Can I hold both ARWR and ACLLY in my portfolio?

ARWR and ACLLY have a correlation of 0.17, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, ARWR or ACLLY?

ARWR has higher volatility (23.10%) compared to ACLLY (11.69%). In terms of maximum drawdown, ARWR dropped -99.24% vs ACLLY's -30.00%.

Which has better risk-adjusted returns?

ARWR currently has the higher Sharpe Ratio (6.69 vs 0.04), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.