ALNY vs. SNY
ALNY (Alnylam Pharmaceuticals, Inc.) and SNY (Sanofi) are both stocks. Both are in the Healthcare sector — ALNY in Biotechnology, SNY in Drug Manufacturers - General. Over the past 10 years, ALNY returned 15.09%/yr vs 4.63%/yr for SNY. At a 0.26 correlation, their price movements are largely independent.
Performance
ALNY vs. SNY - Performance Comparison
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Returns By Period
In the year-to-date period, ALNY achieves a -28.05% return, which is significantly lower than SNY's -6.78% return. Over the past 10 years, ALNY has outperformed SNY with an annualized return of 15.09%, while SNY has yielded a comparatively lower 4.63% annualized return.
ALNY
- 1D
- -3.22%
- 1M
- -3.37%
- YTD
- -28.05%
- 6M
- -38.46%
- 1Y
- -6.52%
- 3Y*
- 13.89%
- 5Y*
- 14.20%
- 10Y*
- 15.09%
SNY
- 1D
- -0.37%
- 1M
- -1.96%
- YTD
- -6.78%
- 6M
- -9.38%
- 1Y
- -8.16%
- 3Y*
- -1.21%
- 5Y*
- 0.44%
- 10Y*
- 4.63%
ALNY vs. SNY - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | |
|---|---|---|---|---|---|---|---|---|---|---|
ALNY Alnylam Pharmaceuticals, Inc. | -28.05% | 68.99% | 22.94% | -19.46% | 40.14% | 30.48% | 12.85% | 57.96% | -42.61% | 239.34% |
SNY Sanofi | -6.78% | 4.93% | 1.09% | 6.55% | 0.57% | 7.00% | 0.39% | 20.47% | 6.06% | 9.96% |
Correlation
The correlation between ALNY and SNY is 0.26, which is low. Their price movements are largely independent, making them effective diversification partners.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.26 |
Correlation (3Y) Calculated over the trailing 3-year period | 0.19 |
Correlation (5Y) Calculated over the trailing 5-year period | 0.18 |
Correlation (10Y) Calculated over the trailing 10-year period | 0.23 |
Correlation (All Time) Calculated using the full available price history since Jun 2, 2004 | 0.26 |
Fundamentals
ALNY:
$39.55B
SNY:
$103.08B
ALNY:
$4.26
SNY:
$3.09
ALNY:
67.11
SNY:
13.86
ALNY:
9.04
SNY:
2.21
ALNY:
36.78
SNY:
1.42
ALNY:
$4.29B
SNY:
$47.35B
ALNY:
$2.51B
SNY:
$34.18B
ALNY:
$729.86M
SNY:
$12.63B
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Return for Risk
ALNY vs. SNY — Risk / Return Rank
ALNY
SNY
ALNY vs. SNY - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for Alnylam Pharmaceuticals, Inc. (ALNY) and Sanofi (SNY). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
| ALNY | SNY | Difference | |
|---|---|---|---|
Sharpe ratioReturn per unit of total volatility | -0.18 | -0.33 | +0.15 |
Sortino ratioReturn per unit of downside risk | -0.01 | -0.28 | +0.28 |
Omega ratioGain probability vs. loss probability | 1.00 | 0.96 | +0.04 |
Calmar ratioReturn relative to maximum drawdown | -0.14 | -0.51 | +0.36 |
Martin ratioReturn relative to average drawdown | -0.27 | -1.01 | +0.75 |
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month. | |||
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Sharpe Ratios by Period
| ALNY | SNY | Difference | |
|---|---|---|---|
Sharpe Ratio (1Y)Calculated over the trailing 1-year period | -0.18 | -0.33 | +0.15 |
Sharpe Ratio (5Y)Calculated over the trailing 5-year period | 0.29 | 0.02 | +0.27 |
Sharpe Ratio (10Y)Calculated over the trailing 10-year period | 0.28 | 0.20 | +0.08 |
Sharpe Ratio (All Time)Calculated using the full available price history | 0.32 | 0.20 | +0.12 |
Drawdowns
ALNY vs. SNY - Drawdown Comparison
The maximum ALNY drawdown since its inception was -83.58%, which is greater than SNY's maximum drawdown of -46.46%. Use the drawdown chart below to compare losses from any high point for ALNY and SNY.
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Drawdown Indicators
| ALNY | SNY | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -83.58% | -46.46% | -37.12% |
Max Drawdown (1Y)Largest decline over 1 year | -42.01% | -16.70% | -25.31% |
Max Drawdown (3Y)Largest decline over 3 years | -42.01% | -23.37% | -18.64% |
Max Drawdown (5Y)Largest decline over 5 years | -42.46% | -33.52% | -8.94% |
Max Drawdown (10Y)Largest decline over 10 years | -59.95% | -33.52% | -26.43% |
Current DrawdownCurrent decline from peak | -41.75% | -20.60% | -21.15% |
Average DrawdownAverage peak-to-trough decline | -30.59% | -12.19% | -18.40% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 22.69% | 8.39% | +14.30% |
Volatility
ALNY vs. SNY - Volatility Comparison
Alnylam Pharmaceuticals, Inc. (ALNY) has a higher volatility of 8.50% compared to Sanofi (SNY) at 5.39%. This indicates that ALNY's price experiences larger fluctuations and is considered to be riskier than SNY based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| ALNY | SNY | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 8.50% | 5.39% | +3.11% |
Volatility (6M)Calculated over the trailing 6-month period | 25.96% | 14.94% | +11.02% |
Volatility (1Y)Calculated over the trailing 1-year period | 36.45% | 24.93% | +11.52% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 48.86% | 24.68% | +24.18% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 53.69% | 23.42% | +30.27% |
Dividends
ALNY vs. SNY - Dividend Comparison
ALNY has not paid dividends to shareholders, while SNY's dividend yield for the trailing twelve months is around 5.66%.
| Position | TTM | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
ALNY Alnylam Pharmaceuticals, Inc. | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% |
SNY Sanofi | 5.66% | 4.56% | 4.22% | 3.83% | 4.32% | 3.80% | 3.61% | 3.47% | 4.29% | 3.82% | 4.11% | 3.77% |
Financials
ALNY vs. SNY - Financials Comparison
This section allows you to compare key financial metrics between Alnylam Pharmaceuticals, Inc. and Sanofi. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.
Total Revenue: Total amount of money received from sales and other business activities
ALNY vs. SNY - Profitability Comparison
ALNY - Gross Margin
Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jun 2026, Alnylam Pharmaceuticals, Inc. reported a gross profit of 0.00 and revenue of 1.17B. Therefore, the gross margin over that period was 0.0%.
SNY - Gross Margin
Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jun 2026, Sanofi reported a gross profit of 8.11B and revenue of 11.24B. Therefore, the gross margin over that period was 72.1%.
ALNY - Operating Margin
Operating margin is calculated as operating income divided by revenue. For the three months ending on Jun 2026, Alnylam Pharmaceuticals, Inc. reported an operating income of 268.64M and revenue of 1.17B, resulting in an operating margin of 23.0%.
SNY - Operating Margin
Operating margin is calculated as operating income divided by revenue. For the three months ending on Jun 2026, Sanofi reported an operating income of 2.27B and revenue of 11.24B, resulting in an operating margin of 20.2%.
ALNY - Net Margin
Net margin is calculated as net income divided by revenue. For the three months ending on Jun 2026, Alnylam Pharmaceuticals, Inc. reported a net income of 205.99M and revenue of 1.17B, resulting in a net margin of 17.7%.
SNY - Net Margin
Net margin is calculated as net income divided by revenue. For the three months ending on Jun 2026, Sanofi reported a net income of 1.61B and revenue of 11.24B, resulting in a net margin of 14.4%.
Frequently Asked Questions
ALNY and SNY have a correlation of 0.26, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
ALNY has higher volatility (8.50%) compared to SNY (5.39%). In terms of maximum drawdown, ALNY dropped -83.58% vs SNY's -46.46%.
ALNY currently has the higher Sharpe Ratio (-0.18 vs -0.33), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
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