ALNY vs. CDTX

Last updated Apr 1, 2026

Compare and contrast key facts about Alnylam Pharmaceuticals, Inc. (ALNY) and Cidara Therapeutics, Inc. (CDTX).

Performance

ALNY vs. CDTX - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Alnylam Pharmaceuticals, Inc. (ALNY) and Cidara Therapeutics, Inc. (CDTX). The values are adjusted to include any dividend payments, if applicable.

ALNY vs. CDTX - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018	2017
ALNY Alnylam Pharmaceuticals, Inc.	-16.79%	68.99%	22.94%	-19.46%	40.14%	30.48%	12.85%	57.96%	-42.61%	239.34%
CDTX Cidara Therapeutics, Inc.	0.22%	721.76%	69.27%	4.98%	-40.45%	-36.50%	-47.92%	63.40%	-65.44%	-34.62%

Fundamentals

Market Cap ALNY : $45.09B CDTX : $3.44B
EPS ALNY : $2.33 CDTX : -$11.88
PB Ratio ALNY : 57.14 CDTX : 8.15
Total Revenue (TTM) ALNY : $3.71B CDTX : $0.00
Gross Profit (TTM) ALNY : $3.04B CDTX : -$45.00M
EBITDA (TTM) ALNY : $472.68M CDTX : -$189.91M

Returns By Period

ALNY

• 1D: 4.68%
• 1M: -0.62%
• YTD: -16.79%
• 6M: -27.44%
• 1Y: 22.54%
• 3Y*: 18.21%
• 5Y*: 18.47%
• 10Y*: 17.71%

CDTX

• 1D: —
• 1M: —
• YTD: —
• 6M: —
• 1Y: —
• 3Y*: —
• 5Y*: —
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

Return for Risk

ALNY vs. CDTX — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

ALNY

ALNY Risk / Return Rank: 58
ALNY Sharpe Ratio Rank: 62
ALNY Sortino Ratio Rank: 58
ALNY Omega Ratio Rank: 57
ALNY Calmar Ratio Rank: 57
ALNY Martin Ratio Rank: 57

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

ALNY vs. CDTX - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Alnylam Pharmaceuticals, Inc. (ALNY) and Cidara Therapeutics, Inc. (CDTX). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	ALNY	CDTX	Difference
Sharpe ratio Return per unit of total volatility	0.55	—	—
Sortino ratio Return per unit of downside risk	1.05	—	—
Omega ratio Gain probability vs. loss probability	1.14	—	—
Calmar ratio Return relative to maximum drawdown	0.62	—	—
Martin ratio Return relative to average drawdown	1.38	—	—
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

Sharpe Ratios by Period

	ALNY	CDTX	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	0.55	—	—
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	0.38	—	—
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	0.33	—	—
Sharpe Ratio (All Time) Calculated using the full available price history	0.34	—	—

Correlation

The correlation between ALNY and CDTX is 0.20, which is considered to be low. This implies their price changes are not closely related. A low correlation is generally favorable for portfolio diversification, as it helps to reduce overall risk by spreading it across multiple assets with different performance patterns.

Dividends

ALNY vs. CDTX - Dividend Comparison

Neither ALNY nor CDTX has paid dividends to shareholders.

Tickers have no history of dividend payments

Drawdowns

Drawdown Indicators

	ALNY	CDTX	Difference
Max Drawdown Largest peak-to-trough decline	-83.58%	—	—
Max Drawdown (1Y) Largest decline over 1 year	-37.57%	—	—
Max Drawdown (5Y) Largest decline over 5 years	-42.46%	—	—
Max Drawdown (10Y) Largest decline over 10 years	-59.95%	—	—
Current Drawdown Current decline from peak	-32.64%	—	—
Average Drawdown Average peak-to-trough decline	-30.53%	—	—
Ulcer Index Depth and duration of drawdowns from previous peaks	16.81%	—	—

Volatility

Volatility by Period

	ALNY	CDTX	Difference
Volatility (1M) Calculated over the trailing 1-month period	10.49%	—	—
Volatility (6M) Calculated over the trailing 6-month period	25.91%	—	—
Volatility (1Y) Calculated over the trailing 1-year period	41.46%	—	—
Volatility (5Y) Calculated over the trailing 5-year period, annualized	48.70%	—	—
Volatility (10Y) Calculated over the trailing 10-year period, annualized	54.25%	—	—

Financials