PortfoliosLab logoPortfoliosLab logo
Alnylam Pharmaceuticals, Inc. (ALNY)
Performance
Return for Risk
Dividends
Drawdowns
Volatility
Financials

Company Info

ISIN
US02043Q1076
CUSIP
02043Q107
IPO Date
May 28, 2004

Highlights

Market Cap
$45.09B
Enterprise Value
$46.62B
EPS (TTM)
$2.33
PE Ratio
141.77
Total Revenue (TTM)
$3.71B
Gross Profit (TTM)
$3.04B
EBITDA (TTM)
$472.68M
Year Range
$205.87 - $495.55
Target Price
$463.06
ROA (TTM)
6.32%
ROE (TTM)
39.76%

Share Price Chart


Loading graphics...

Compare stocks, funds, or ETFs

Search for stocks, ETFs, and funds for a quick comparison or use the comparison tool for more options.


Performance

Performance Chart

The chart shows the growth of an initial investment of $10,000 in Alnylam Pharmaceuticals, Inc., comparing it to the performance of the S&P 500 index or another benchmark. All prices have been adjusted for splits and dividends.


Loading graphics...

S&P 500 Index

Returns By Period

Alnylam Pharmaceuticals, Inc. (ALNY) has returned -16.79% so far this year and 22.54% over the past 12 months. Looking at the last ten years, ALNY has achieved an annualized return of 17.71%, outperforming the S&P 500 Index benchmark, which averaged 12.16% per year.


Alnylam Pharmaceuticals, Inc.

1D
4.68%
1M
-0.62%
YTD
-16.79%
6M
-27.44%
1Y
22.54%
3Y*
18.21%
5Y*
18.47%
10Y*
17.71%

Benchmark (S&P 500 Index)

1D
2.91%
1M
-5.09%
YTD
-4.63%
6M
-2.39%
1Y
16.33%
3Y*
16.69%
5Y*
10.18%
10Y*
12.16%
*Multi-year figures are annualized to reflect compound growth (CAGR)

Monthly Returns

Based on dividend-adjusted daily data since Jun 1, 2004, ALNY's average daily return is +0.13%, while the average monthly return is +2.66%. At this rate, your investment would double in approximately 2.2 years.

Historically, 54% of months were positive and 46% were negative. The best month was Jun 2024 with a return of +63.7%, while the worst month was Oct 2016 at -47.5%. The longest winning streak lasted 8 consecutive months, and the longest losing streak was 5 months.

On a daily basis, ALNY closed higher 51% of trading days. The best single day was Jul 16, 2012 with a return of +53.0%, while the worst single day was Oct 6, 2016 at -48.5%.


JanFebMarAprMayJunJulAugSepOctNovDecTotal
2026-14.99%-1.52%-0.62%-16.79%
202515.30%-9.05%9.43%-2.51%15.70%7.07%20.29%13.84%2.13%0.01%-1.05%-11.87%68.99%
2024-9.67%-12.62%-1.09%-3.68%3.11%63.71%-2.28%10.62%4.70%-3.07%-5.07%-7.02%22.94%
2023-4.73%-15.44%4.63%-0.56%-7.12%2.66%2.87%1.24%-10.47%-14.29%10.84%13.77%-19.46%
2022-18.86%14.72%3.45%-18.29%-5.72%15.94%-2.61%45.50%-3.15%3.55%6.43%7.73%40.14%
202115.78%-1.58%-4.67%-0.39%0.96%19.39%5.56%12.57%-6.27%-15.49%15.19%-7.74%30.48%

Benchmark Metrics

Alnylam Pharmaceuticals, Inc. has an annualized alpha of 25.60%, beta of 1.09, and R² of 0.13 versus S&P 500 Index. Calculated based on daily prices since June 02, 2004.

  • This stock captured 206.02% of S&P 500 Index gains and 138.74% of its losses — amplifying both gains and losses, but participating more in upside than downside.
  • R² of 0.13 means this stock moves largely independently of S&P 500 Index — capture ratios reflect limited market correlation rather than active downside protection. Consider using a more representative benchmark.

Alpha
25.60%
Beta
1.09
0.13
Upside Capture
206.02%
Downside Capture
138.74%

Return for Risk

Risk / Return Rank

ALNY ranks 56 for risk / return — on par with similar stocks. You're getting a typical balance of risk and reward. Not a standout, but not a red flag either — a reasonable choice if other factors align with your goals.


ALNY Risk / Return Rank: 5656
Overall Rank
ALNY Sharpe Ratio Rank: 6060
Sharpe Ratio Rank
ALNY Sortino Ratio Rank: 5656
Sortino Ratio Rank
ALNY Omega Ratio Rank: 5555
Omega Ratio Rank
ALNY Calmar Ratio Rank: 5555
Calmar Ratio Rank
ALNY Martin Ratio Rank: 5555
Martin Ratio Rank
The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

Return / Risk — by metrics

The table below present risk-adjusted performance metrics for Alnylam Pharmaceuticals, Inc. (ALNY) and compare them to a chosen benchmark (S&P 500 Index).


ALNYBenchmarkDifference

Sharpe ratio

Return per unit of total volatility

0.55

0.90

-0.35

Sortino ratio

Return per unit of downside risk

1.05

1.39

-0.33

Omega ratio

Gain probability vs. loss probability

1.14

1.21

-0.07

Calmar ratio

Return relative to maximum drawdown

0.62

1.40

-0.78

Martin ratio

Return relative to average drawdown

1.38

6.61

-5.22

Explore ALNY risk-adjusted metrics in detail

Dive deeper into individual metrics with historical trends, benchmark comparisons, and performance across different time periods.

Dividends

Dividend History


Alnylam Pharmaceuticals, Inc. doesn't pay dividends

Drawdowns

Drawdowns Chart

The Drawdowns chart displays portfolio losses from any high point along the way. Drawdowns are calculated considering price movements and all distributions paid, if any.


Loading graphics...

Worst Drawdowns

The table below displays the maximum drawdowns of the Alnylam Pharmaceuticals, Inc.. A maximum drawdown is a measure of risk, indicating the largest reduction in portfolio value due to a series of losing trades.

The maximum drawdown for the Alnylam Pharmaceuticals, Inc. was 83.58%, occurring on Oct 3, 2011. Recovery took 439 trading sessions.

The current Alnylam Pharmaceuticals, Inc. drawdown is 32.64%.


Depth

Start

To Bottom

Bottom

To Recover

End

Total

-83.58%Oct 10, 20071004Oct 3, 2011439Jul 3, 20131443
-77.36%Jun 23, 2015347Nov 3, 2016257Nov 10, 2017604
-57.81%Mar 21, 2018193Dec 24, 2018374Jun 19, 2020567
-52.18%Jun 10, 200446Aug 16, 2004100Jan 6, 2005146
-47.61%Jan 14, 201472Apr 28, 2014126Oct 24, 2014198

Volatility

Volatility Chart

The chart below shows the rolling one-month volatility.


Loading graphics...

Financials

Financial Performance

The chart below illustrates the trends in the financial health of Alnylam Pharmaceuticals, Inc. over time, highlighting three key metrics: Total Revenue, Earnings Before Interest and Taxes (EBIT), and Net Income.


Annual
Quarterly

0.0

Valuation

The Valuation section provides an overview of how Alnylam Pharmaceuticals, Inc. is priced in the market compared to other companies in the Biotechnology industry. It includes key financial ratios that help investors assess whether the stock is undervalued or overvalued.


PE Ratio

The chart displays the Price-to-Earnings (P/E) ratio for ALNY, comparing it with other companies in the Biotechnology industry. Currently, ALNY has a P/E ratio of 141.8. This P/E ratio is significantly higher than those of industry peers. This could indicate that the stock is overvalued or that investors expect strong future growth.

PS Ratio

This chart shows the Price-to-Sales (P/S) ratio for ALNY relative to other companies in the Biotechnology industry. Currently, ALNY has a P/S ratio of 12.0. This P/S ratio falls within the average range for the industry, suggesting the stock is fairly valued based on its revenue.

PB Ratio

The chart illustrates the Price-to-Book (P/B) ratio for ALNY in comparison with other companies in the Biotechnology industry. Currently, ALNY has a P/B value of 57.1. This P/B ratio is higher than most companies in the industry. It may suggest the stock is overvalued or that investors expect the company to generate high returns on its assets.

Income Statement



TTM
Revenue

Total Revenue

Cost Of Revenue

Gross Profit

Operating Expenses

Selling, General & Admin Expenses

R&D Expenses

Depreciation And Amortization

Total Operating Expenses

Income

Income Before Tax

Operating Income

EBITDA

EBIT

Earnings From Continuing Operations

Net Income

Income Tax Expense

Other Non-Operating Income (Expenses)

Extraordinary Items

Discontinued Operations

Effect Of Accounting Charges

Non Recurring

Minority Interest

Other Items

Interest Income

Interest Expense

Net Interest Income

Values in undefined except per share items