Roundhill Glp-1 & Weight Loss ETF (OZEM) Alternatives
Roundhill Glp-1 & Weight Loss ETF (OZEM) belongs to the Health & Biotech Equities category. Below you'll find alternative ETFs from the same category, ranked by key criteria, plus funds that investors commonly compare with OZEM. Use the tables to find lower-cost options, better risk-adjusted returns, or funds that fit a different role in your portfolio.
Cheapest Alternatives to OZEM
OZEM charges 0.59% annually. Among ETFs in the Health & Biotech Equities category, these options have the lowest expense ratios among OZEM alternatives.
| Symbol | Name | Expense Ratio | Inception | |
|---|---|---|---|---|
| Fidelity MSCI Health Care Index ETF | 0.08% | Oct 21, 2013 | OZEM vs FHLC | |
| State Street Health Care Select Sector SPDR ETF | 0.08% | Dec 16, 1998 | OZEM vs XLV | |
| Vanguard Health Care ETF | 0.10% | Jan 26, 2004 | OZEM vs VHT | |
| Invesco S&P SmallCap Health Care ETF | 0.29% | Apr 7, 2010 | OZEM vs PSCH | |
| SPDR S&P Pharmaceuticals ETF | 0.35% | Jun 19, 2006 | OZEM vs XPH |
Best Risk-Adjusted Alternatives to OZEM
Among ETFs in the Health & Biotech Equities category, these options rank highest on PortfoliosLab's risk-adjusted score, which accounts for volatility, drawdown, and return consistency over a 1-year period.
| Symbol | Name | Risk / Return Rank | Inception | |
|---|---|---|---|---|
| Virtus LifeSci Biotech Clinical Trials ETF | 97 | Dec 16, 2014 | OZEM vs BBC | |
| ALPS Medical Breakthroughs ETF | 95 | Dec 31, 2014 | OZEM vs SBIO | |
| SPDR S&P Biotech ETF | 92 | Feb 6, 2006 | OZEM vs XBI | |
| Tema Oncology ETF | 90 | Aug 14, 2023 | OZEM vs CANC | |
| F/m Emerald Life Sciences Innovation ETF | 86 | Oct 30, 2024 | OZEM vs LFSC |
Top Performing OZEM Alternatives (YTD)
OZEM alternatives from the Health & Biotech Equities category, sorted by year-to-date return.
| Symbol | Name | YTD Return | Inception | |
|---|---|---|---|---|
| iShares Genomics Immunology and Healthcare ETF Gen... | 10.92% | Jun 11, 2019 | OZEM vs IDNA | |
| Virtus LifeSci Biotech Clinical Trials ETF | 7.95% | Dec 16, 2014 | OZEM vs BBC | |
| Tema Oncology ETF | 5.69% | Aug 14, 2023 | OZEM vs CANC | |
| SPDR S&P Biotech ETF | 4.76% | Feb 6, 2006 | OZEM vs XBI | |
| First Trust Nasdaq Pharmaceuticals ETF | 4.48% | Sep 20, 2016 | OZEM vs FTXH |
Lowest Volatility Alternatives to OZEM
OZEM alternatives from the Health & Biotech Equities category, sorted by annualized volatility over the past year.
| Symbol | Name | Volatility 1Y | Inception | |
|---|---|---|---|---|
| Principal Healthcare Innovators Index ETF | 0.00% | Aug 19, 2016 | OZEM vs BTEC | |
| Loncar Cancer Immunotherapy ETF | 0.00% | Oct 13, 2015 | OZEM vs CNCR | |
| Amplify Treatments, Testing and Advancements ETF | 0.00% | Jun 17, 2020 | OZEM vs GERM | |
| Horizon Kinetics SPAC Active ETF | 8.60% | Jun 29, 2007 | OZEM vs SPAQ | |
| Global X Aging Population ETF | 15.94% | May 9, 2016 | OZEM vs AGNG |
Lowest Drawdown Alternatives to OZEM
OZEM alternatives from the Health & Biotech Equities category, sorted by maximum drawdown over the past year.
| Symbol | Name | Max Drawdown 1Y | Inception | |
|---|---|---|---|---|
| Amplify Treatments, Testing and Advancements ETF | 0.00% | Jun 17, 2020 | OZEM vs GERM | |
| Horizon Kinetics SPAC Active ETF | -5.30% | Jun 29, 2007 | OZEM vs SPAQ | |
| Jpmorgan Healthcare Leaders ETF | -9.68% | Nov 1, 2023 | OZEM vs JDOC | |
| VanEck Vectors Pharmaceutical ETF | -10.02% | Dec 20, 2011 | OZEM vs PPH | |
| Global X Aging Population ETF | -10.16% | May 9, 2016 | OZEM vs AGNG |
Other ETFs from Roundhill
Most popular Roundhill ETFs on PortfoliosLab, across asset classes.
| Symbol | Name | Category | Risk / Return Rank | YTD Return | Inception | |
|---|---|---|---|---|---|---|
| Roundhill Magnificent Seven ETF | Technology Equities | 62 | -12.16% | Apr 10, 2023 | OZEM vs MAGS | |
| Roundhill ETF Trust - Roundhill N-100 0DTE Covered... | Large Cap Blend Equities | 60 | -5.34% | Mar 6, 2024 | OZEM vs QDTE | |
| Roundhill S&P 500 0DTE Covered Call Strategy ETF | Derivative Income, S&P 500 | 48 | -3.43% | Mar 7, 2024 | OZEM vs XDTE | |
| Roundhill Bitcoin Covered Call Strategy ETF | Cryptocurrency | 7 | -18.34% | Jan 17, 2024 | OZEM vs YBTC | |
| Roundhill Generative AI & Technology ETF | Technology Equities | 95 | 4.90% | May 17, 2023 | OZEM vs CHAT | |
| Roundhill Daily 2X Long Magnificent Seven ETF | Leveraged Equities, Leveraged | 45 | -25.26% | Feb 28, 2024 | OZEM vs MAGX | |
| Roundhill WeeklyPay™ Universe ETF | Derivative Income | — | -10.65% | Sep 3, 2025 | OZEM vs WPAY | |
| PLTR WeeklyPay™ ETF | Derivative Income | 61 | -22.36% | Feb 18, 2025 | OZEM vs PLTW | |
| Roundhill Magnificent Seven Covered Call ETF | Derivative Income | — | -9.64% | Apr 23, 2025 | OZEM vs MAGY | |
| Roundhill Small Cap 0DTE Covered Call Strategy ETF | Derivative Income | 50 | 0.31% | Sep 9, 2024 | OZEM vs RDTE |
Often Compared With OZEM
What investors most often compare with OZEM, based on PortfoliosLab usage data.
Compare OZEM with Any Fund or Stock
Compare OZEM with any ETF, mutual fund, or stock using PortfoliosLab's comparison tool.