OZEM vs. GERM

Last updated Jun 25, 2026

OZEM (Roundhill Glp-1 & Weight Loss ETF) and GERM (Amplify Treatments, Testing and Advancements ETF) are both Health & Biotech Equities funds. OZEM is actively managed, while GERM is passively managed. Over the past year, OZEM returned 23.16% vs 0.00% for GERM. OZEM charges 0.59%/yr vs 0.68%/yr for GERM.

Performance

OZEM vs. GERM - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Roundhill Glp-1 & Weight Loss ETF (OZEM) and Amplify Treatments, Testing and Advancements ETF (GERM). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

OZEM

• 1D: 0.96%
• 1M: 1.18%
• YTD: -7.52%
• 6M: -9.97%
• 1Y: 23.16%
• 3Y*: —
• 5Y*: —
• 10Y*: —

GERM

• 1D: 0.00%
• 1M: 0.00%
• YTD: 0.00%
• 6M: 0.00%
• 1Y: 0.00%
• 3Y*: —
• 5Y*: —
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

OZEM vs. GERM - Yearly Performance Comparison

	2026 (YTD)	2025	2024
OZEM Roundhill Glp-1 & Weight Loss ETF	-7.52%	41.87%	-11.26%
GERM Amplify Treatments, Testing and Advancements ETF	0.00%	0.00%	0.00%

OZEM vs. GERM - Sectors Allocation Comparison

Sectors	OZEM	GERM
Healthcare	100.0%	99.3%
Financial Services	0.1%	0.4%
Basic Materials	-	-
Communication Services	-	-
Consumer Cyclical	-	-
Consumer Defensive	-	-
Energy	-	-
Industrials	-	-
Real Estate	-	-
Technology	-	-
Utilities	-	-

Return for Risk

OZEM vs. GERM — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

OZEM

OZEM Risk / Return Rank: 27
OZEM Sharpe Ratio Rank: 30
OZEM Sortino Ratio Rank: 29
OZEM Omega Ratio Rank: 28
OZEM Calmar Ratio Rank: 27
OZEM Martin Ratio Rank: 22

GERM

Risk / return metrics aren't available yet — we need at least 12 months of trading data to calculate them.

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

OZEM vs. GERM - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Roundhill Glp-1 & Weight Loss ETF (OZEM) and Amplify Treatments, Testing and Advancements ETF (GERM). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.

	OZEM	GERM	Difference
Sharpe ratio: Return per unit of total volatility	0.97	—	—
Sortino ratio: Return per unit of downside risk	1.47	—	—
Omega ratio: Gain probability vs. loss probability	1.18	—	—
Calmar ratio: Return relative to maximum drawdown	1.19	—	—
Martin ratio: Return relative to average drawdown	2.44	—	—

Drawdowns

OZEM vs. GERM - Drawdown Comparison

The maximum OZEM drawdown since its inception was -28.65%, which is greater than GERM's maximum drawdown of 0.00%. Use the drawdown chart below to compare losses from any high point for OZEM and GERM.

Drawdown Indicators

	OZEM	GERM	Difference
Max Drawdown Largest peak-to-trough decline	-28.65%	0.00%	-28.65%
Max Drawdown (1Y) Largest decline over 1 year	-19.50%	0.00%	-19.50%
Current Drawdown Current decline from peak	-14.65%	0.00%	-14.65%
Average Drawdown Average peak-to-trough decline	-9.11%	0.00%	-9.11%
Ulcer Index Depth and duration of drawdowns from previous peaks	9.54%	0.00%	+9.54%

Volatility

OZEM vs. GERM - Volatility Comparison

Roundhill Glp-1 & Weight Loss ETF (OZEM) has a higher volatility of 7.11% compared to Amplify Treatments, Testing and Advancements ETF (GERM) at 0.00%. This indicates that OZEM's price experiences larger fluctuations and is considered to be riskier than GERM based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	OZEM	GERM	Difference
Volatility (1M) Calculated over the trailing 1-month period	7.11%	0.00%	+7.11%
Volatility (6M) Calculated over the trailing 6-month period	16.66%	0.00%	+16.66%
Volatility (1Y) Calculated over the trailing 1-year period	24.03%	0.00%	+24.03%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	25.01%	0.00%	+25.01%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	25.01%	0.00%	+25.01%

OZEM vs. GERM - Expense Ratio Comparison

OZEM has a 0.59% expense ratio, which is lower than GERM's 0.68% expense ratio.

Dividends

OZEM vs. GERM - Dividend Comparison

OZEM's dividend yield for the trailing twelve months is around 1.30%, while GERM has not paid dividends to shareholders.

Position	TTM	2025	2024
GERM Amplify Treatments, Testing and Advancements ETF	0.00%	0.00%	0.00%
OZEM Roundhill Glp-1 & Weight Loss ETF	1.30%	1.20%	0.22%

Frequently Asked Questions

Which is riskier, OZEM or GERM?

OZEM has higher volatility (7.11%) compared to GERM (0.00%). In terms of maximum drawdown, OZEM dropped -28.65% vs GERM's 0.00%.

Which ETF is better, OZEM or GERM?

On 1-year performance, OZEM leads with 23.16% vs 0.00% for GERM. On fees, OZEM is cheaper at 0.59% per year. On volatility, GERM has been the lower-risk option at 0.00%. The better choice depends on whether you care most about return, fees, risk, or income.

Which ETF has performed better, OZEM or GERM?

Over the 1-year period, OZEM has performed better with a 23.16% return vs 0.00%. Past performance does not guarantee future results, so compare this with risk, fees, and fund exposure.

Which ETF is cheaper, OZEM or GERM?

OZEM is cheaper with a 0.59% expense ratio, compared with 0.68% for GERM.

Which ETF pays a higher dividend yield, OZEM or GERM?

OZEM has the higher dividend yield at 1.30%, compared with 0.00% for GERM.

What is the main difference between OZEM and GERM?

They also come from different issuers: Roundhill and Amplify. Their fees differ too: 0.59% for OZEM and 0.68% for GERM.