OZEM vs. GERM

Last updated Jun 4, 2026

OZEM (Roundhill Glp-1 & Weight Loss ETF) and GERM (Amplify Treatments, Testing and Advancements ETF) are both Health & Biotech Equities funds. OZEM is actively managed, while GERM is passively managed. Over the past year, OZEM returned 21.16% vs 0.00% for GERM. OZEM charges 0.59%/yr vs 0.68%/yr for GERM.

Performance

OZEM vs. GERM - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Roundhill Glp-1 & Weight Loss ETF (OZEM) and Amplify Treatments, Testing and Advancements ETF (GERM). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

OZEM

• 1D: -0.73%
• 1M: -4.02%
• YTD: -11.95%
• 6M: -5.58%
• 1Y: 21.16%
• 3Y*: —
• 5Y*: —
• 10Y*: —

GERM

• 1D: 0.00%
• 1M: 0.00%
• YTD: 0.00%
• 6M: 0.00%
• 1Y: 0.00%
• 3Y*: —
• 5Y*: —
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

OZEM vs. GERM - Yearly Performance Comparison

	2026 (YTD)	2025	2024
OZEM Roundhill Glp-1 & Weight Loss ETF	-11.95%	41.87%	-11.03%
GERM Amplify Treatments, Testing and Advancements ETF	0.00%	0.00%	0.00%

OZEM vs. GERM - Sectors Allocation Comparison

Sectors	OZEM	GERM
Healthcare	100.0%	99.3%
Financial Services	0.1%	0.4%
Basic Materials	-	-
Communication Services	-	-
Consumer Cyclical	-	-
Consumer Defensive	-	-
Energy	-	-
Industrials	-	-
Real Estate	-	-
Technology	-	-
Utilities	-	-

Return for Risk

OZEM vs. GERM — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

OZEM

OZEM Risk / Return Rank: 23
OZEM Sharpe Ratio Rank: 24
OZEM Sortino Ratio Rank: 25
OZEM Omega Ratio Rank: 24
OZEM Calmar Ratio Rank: 24
OZEM Martin Ratio Rank: 20

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

OZEM vs. GERM - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Roundhill Glp-1 & Weight Loss ETF (OZEM) and Amplify Treatments, Testing and Advancements ETF (GERM). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	OZEM	GERM	Difference
Sharpe ratio: Return per unit of total volatility	0.87	—	—
Sortino ratio: Return per unit of downside risk	1.34	—	—
Omega ratio: Gain probability vs. loss probability	1.16	—	—
Calmar ratio: Return relative to maximum drawdown	1.11	—	—
Martin ratio: Return relative to average drawdown	2.30	—	—
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

Sharpe Ratios by Period

	OZEM	GERM	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	0.87	—	—
Sharpe Ratio (All Time) Calculated using the full available price history	0.38	—	—

Drawdowns

OZEM vs. GERM - Drawdown Comparison

The maximum OZEM drawdown since its inception was -28.65%, which is greater than GERM's maximum drawdown of 0.00%. Use the drawdown chart below to compare losses from any high point for OZEM and GERM.

Drawdown Indicators

	OZEM	GERM	Difference
Max Drawdown Largest peak-to-trough decline	-28.65%	0.00%	-28.65%
Max Drawdown (1Y) Largest decline over 1 year	-19.16%	0.00%	-19.16%
Current Drawdown Current decline from peak	-18.74%	0.00%	-18.74%
Average Drawdown Average peak-to-trough decline	-8.90%	0.00%	-8.90%
Ulcer Index Depth and duration of drawdowns from previous peaks	9.22%	0.00%	+9.22%

Volatility

OZEM vs. GERM - Volatility Comparison

Roundhill Glp-1 & Weight Loss ETF (OZEM) has a higher volatility of 5.67% compared to Amplify Treatments, Testing and Advancements ETF (GERM) at 0.00%. This indicates that OZEM's price experiences larger fluctuations and is considered to be riskier than GERM based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	OZEM	GERM	Difference
Volatility (1M) Calculated over the trailing 1-month period	5.67%	0.00%	+5.67%
Volatility (6M) Calculated over the trailing 6-month period	17.15%	0.00%	+17.15%
Volatility (1Y) Calculated over the trailing 1-year period	24.46%	0.00%	+24.46%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	25.04%	0.00%	+25.04%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	25.04%	0.00%	+25.04%

OZEM vs. GERM - Expense Ratio Comparison

OZEM has a 0.59% expense ratio, which is lower than GERM's 0.68% expense ratio.

Dividends

OZEM vs. GERM - Dividend Comparison

OZEM's dividend yield for the trailing twelve months is around 1.36%, while GERM has not paid dividends to shareholders.

Position	TTM	2025	2024
GERM Amplify Treatments, Testing and Advancements ETF	0.00%	0.00%	0.00%
OZEM Roundhill Glp-1 & Weight Loss ETF	1.36%	1.20%	0.22%

Frequently Asked Questions

Which is riskier, OZEM or GERM?

OZEM has higher volatility (5.67%) compared to GERM (0.00%). In terms of maximum drawdown, OZEM dropped -28.65% vs GERM's 0.00%.

Which ETF is better, OZEM or GERM?

On 1-year performance, OZEM leads with 21.16% vs 0.00% for GERM. On fees, OZEM is cheaper at 0.59% per year. On volatility, GERM has been the lower-risk option at 0.00%. The better choice depends on whether you care most about return, fees, risk, or income.

Which ETF has performed better, OZEM or GERM?

Over the 1-year period, OZEM has performed better with a 21.16% return vs 0.00%. Past performance does not guarantee future results, so compare this with risk, fees, and fund exposure.

Which ETF is cheaper, OZEM or GERM?

OZEM is cheaper with a 0.59% expense ratio, compared with 0.68% for GERM.

Which ETF pays a higher dividend yield, OZEM or GERM?

OZEM has the higher dividend yield at 1.36%, compared with 0.00% for GERM.

What is the main difference between OZEM and GERM?

They also come from different issuers: Roundhill and Amplify. Their fees differ too: 0.59% for OZEM and 0.68% for GERM.