WEBs Health Care XLV Defined Volatility ETF (DVXV) belongs to the Health & Biotech Equities category. Below you'll find alternative ETFs from the same category, ranked by key criteria, plus funds that investors commonly compare with DVXV. Use the tables to find lower-cost options, better risk-adjusted returns, or a closer substitute for your current allocation.
Cheapest Alternatives to DVXV
DVXV charges 0.89% annually. There are 60 ETFs in the Health & Biotech Equities category with lower expense ratios, going as low as 0.08%.
| Symbol | Name | Expense Ratio | AUM | Inception | |
|---|---|---|---|---|---|
| Fidelity MSCI Health Care Index ETF | 0.08% | 3.22B | Oct 2013 | DVXV vs FHLC | |
| State Street Health Care Select Sector SPDR ETF | 0.08% | 41.65B | Dec 1998 | DVXV vs XLV | |
| Vanguard Health Care ETF | 0.09% | 19.00B | Jan 2004 | DVXV vs VHT | |
| Portfolio Building Block World Pharma and Biotech ... | 0.13% | 951.16M | Nov 2025 | DVXV vs PBPH | |
| GSK plc ADRhedged ETF | 0.19% | 793.18K | Jan 2025 | DVXV vs GSKH |
Best Risk-Adjusted Alternatives to DVXV
Among 56 ETFs in the Health & Biotech Equities category with risk / return rank data, the top risk-adjusted alternatives shown here go as high as 96.
| Symbol | Name | Risk / Return Rank | AUM | Inception | |
|---|---|---|---|---|---|
| Virtus LifeSci Biotech Clinical Trials ETF | 96 | 57.56M | Dec 2014 | DVXV vs BBC | |
| ALPS Medical Breakthroughs ETF | 94 | 213.08M | Dec 2014 | DVXV vs SBIO | |
| First Trust Nasdaq Pharmaceuticals ETF | 94 | 36.36M | Sep 2016 | DVXV vs FTXH | |
| iShares U.S. Pharmaceuticals ETF | 93 | 1.34B | May 2006 | DVXV vs IHE | |
| SPDR S&P Biotech ETF | 93 | 11.10B | Feb 2006 | DVXV vs XBI |
Top Performing DVXV Alternatives (YTD)
DVXV is at 4.43% YTD. There are 46 ETFs in the Health & Biotech Equities category with higher YTD returns, going as high as 41.35%.
| Symbol | Name | YTD Return | AUM | Inception | |
|---|---|---|---|---|---|
| AdvisorShares Psychedelics ETF | 41.35% | 44.37M | Sep 2021 | DVXV vs PSIL | |
| ARK Genomic Revolution Multi-Sector ETF | 38.38% | 1.31B | Oct 2014 | DVXV vs ARKG | |
| Roundhill UNH WeeklyPay ETF | 31.46% | 6.01M | Dec 2025 | DVXV vs UNHW | |
| Virtus LifeSci Biotech Clinical Trials ETF | 29.44% | 57.56M | Dec 2014 | DVXV vs BBC | |
| SPDR S&P Health Care Services ETF | 26.76% | 204.10M | Sep 2011 | DVXV vs XHS |
Lowest Volatility Alternatives to DVXV
DVXV has 21.62% 1-year volatility. There are 41 ETFs in the Health & Biotech Equities category with lower 1-year volatility, going as low as 0.00%.
| Symbol | Name | Volatility 1Y | AUM | Inception | |
|---|---|---|---|---|---|
| Loncar Cancer Immunotherapy ETF | 0.00% | 12.73M | Oct 2015 | DVXV vs CNCR | |
| Amplify Treatments, Testing and Advancements ETF | 0.00% | 9.68M | Jun 2020 | DVXV vs GERM | |
| Horizon Kinetics SPAC Active ETF | 8.62% | 10.11M | Jun 2007 | DVXV vs SPAQ | |
| State Street Health Care Select Sector SPDR Premiu... | 11.06% | 16.78M | Jul 2025 | DVXV vs XLVI | |
| Milliman Healthcare Inflation Plus ETF | 11.54% | 982.35K | Apr 2026 | DVXV vs MHIP |
Lowest Drawdown Alternatives to DVXV
Among 57 ETFs in the Health & Biotech Equities category with 1-year drawdown data, the lowest-drawdown alternatives shown here go as shallow as 0.00%.
| Symbol | Name | Max Drawdown 1Y | AUM | Inception | |
|---|---|---|---|---|---|
| Amplify Treatments, Testing and Advancements ETF | 0.00% | 9.68M | Jun 2020 | DVXV vs GERM | |
| Horizon Kinetics SPAC Active ETF | -4.32% | 10.11M | Jun 2007 | DVXV vs SPAQ | |
| First Trust Nasdaq Pharmaceuticals ETF | -7.47% | 36.36M | Sep 2016 | DVXV vs FTXH | |
| Invesco Nasdaq Biotechnology ETF | -8.34% | 74.65M | Jun 2021 | DVXV vs IBBQ | |
| iShares U.S. Pharmaceuticals ETF | -8.47% | 1.34B | May 2006 | DVXV vs IHE |
Other ETFs from WEBs
The 10 most viewed WEBs ETFs shown here include DVQQ, DVXE, DVUT and span 11 categories. AUM among these funds goes as high as $3M.
Often Compared With DVXV
Investors most often compare DVXV with DVRE, DVXC, BBH. These 14 comparison targets span 3 categories, based on PortfoliosLab usage data.
Compare DVXV with Any Fund or Stock
Compare DVXV with any ETF, mutual fund, or stock using PortfoliosLab's comparison tool.
Pair DVXV with funds that move differently
WEBs Health Care XLV Defined Volatility ETF alternatives help with substitution. Diversifiers are the next step when you want funds with lower historical correlation to DVXV.
Explore DVXV Diversifiers