WEBs Health Care XLV Defined Volatility ETF (DVXV) belongs to the Health & Biotech Equities category. Below you'll find alternative ETFs from the same category, ranked by key criteria, plus funds that investors commonly compare with DVXV. Use the tables to find lower-cost options, better risk-adjusted returns, or a closer substitute for your current allocation.
Cheapest Alternatives to DVXV
DVXV charges 0.89% annually. There are 57 ETFs in the Health & Biotech Equities category with lower expense ratios, going as low as 0.08%.
| Symbol | Name | Expense Ratio | AUM | Inception | |
|---|---|---|---|---|---|
| Fidelity MSCI Health Care Index ETF | 0.08% | 2.85B | Oct 2013 | DVXV vs FHLC | |
| State Street Health Care Select Sector SPDR ETF | 0.08% | 38.66B | Dec 1998 | DVXV vs XLV | |
| Vanguard Health Care ETF | 0.09% | 18.50B | Jan 2004 | DVXV vs VHT | |
| Portfolio Building Block World Pharma and Biotech ... | 0.13% | 9.98M | Nov 2025 | DVXV vs PBPH | |
| Invesco S&P SmallCap Health Care ETF | 0.29% | 131.36M | Apr 2010 | DVXV vs PSCH |
Best Risk-Adjusted Alternatives to DVXV
Among 54 ETFs in the Health & Biotech Equities category with risk / return rank data, the top risk-adjusted alternatives shown here go as high as 89.
| Symbol | Name | Risk / Return Rank | AUM | Inception | |
|---|---|---|---|---|---|
| Virtus LifeSci Biotech Clinical Trials ETF | 89 | 43.63M | Dec 2014 | DVXV vs BBC | |
| SPDR S&P Biotech ETF | 74 | 8.28B | Feb 2006 | DVXV vs XBI | |
| iShares U.S. Pharmaceuticals ETF | 74 | 912.87M | May 2006 | DVXV vs IHE | |
| ALPS Medical Breakthroughs ETF | 72 | 161.79M | Dec 2014 | DVXV vs SBIO | |
| First Trust Nasdaq Pharmaceuticals ETF | 71 | 35.04M | Sep 2016 | DVXV vs FTXH |
Top Performing DVXV Alternatives (YTD)
DVXV is at -6.26% YTD. There are 49 ETFs in the Health & Biotech Equities category with higher YTD returns, going as high as 20.15%.
| Symbol | Name | YTD Return | AUM | Inception | |
|---|---|---|---|---|---|
| AdvisorShares Psychedelics ETF | 20.15% | 35.56M | Sep 2021 | DVXV vs PSIL | |
| ARK Genomic Revolution Multi-Sector ETF | 17.09% | 1.24B | Oct 2014 | DVXV vs ARKG | |
| Roundhill UNH WeeklyPay ETF | 15.08% | 4.48M | Dec 2025 | DVXV vs UNHW | |
| iShares Genomics Immunology and Healthcare ETF Gen... | 10.31% | 163.14M | Jun 2019 | DVXV vs IDNA | |
| Virtus LifeSci Biotech Clinical Trials ETF | 8.64% | 43.63M | Dec 2014 | DVXV vs BBC |
Lowest Volatility Alternatives to DVXV
DVXV has 21.33% 1-year volatility. There are 39 ETFs in the Health & Biotech Equities category with lower 1-year volatility, going as low as 0.00%.
| Symbol | Name | Volatility 1Y | AUM | Inception | |
|---|---|---|---|---|---|
| Principal Healthcare Innovators Index ETF | 0.00% | 16.16M | Aug 2016 | DVXV vs BTEC | |
| Amplify Treatments, Testing and Advancements ETF | 0.00% | 9.68M | Jun 2020 | DVXV vs GERM | |
| Loncar Cancer Immunotherapy ETF | 0.00% | 12.73M | Oct 2015 | DVXV vs CNCR | |
| Horizon Kinetics SPAC Active ETF | 8.80% | 10.01M | Jun 2007 | DVXV vs SPAQ | |
| State Street Health Care Select Sector SPDR Premiu... | 10.94% | 14.25M | Jul 2025 | DVXV vs XLVI |
Lowest Drawdown Alternatives to DVXV
Among 55 ETFs in the Health & Biotech Equities category with 1-year drawdown data, the lowest-drawdown alternatives shown here go as shallow as 0.00%.
| Symbol | Name | Max Drawdown 1Y | AUM | Inception | |
|---|---|---|---|---|---|
| Amplify Treatments, Testing and Advancements ETF | 0.00% | 9.68M | Jun 2020 | DVXV vs GERM | |
| Horizon Kinetics SPAC Active ETF | -5.30% | 10.01M | Jun 2007 | DVXV vs SPAQ | |
| First Trust Nasdaq Pharmaceuticals ETF | -7.47% | 35.04M | Sep 2016 | DVXV vs FTXH | |
| Invesco Nasdaq Biotechnology ETF | -8.34% | 67.37M | Jun 2021 | DVXV vs IBBQ | |
| iShares U.S. Pharmaceuticals ETF | -8.47% | 912.87M | May 2006 | DVXV vs IHE |
Other ETFs from WEBs
The 10 most viewed WEBs ETFs shown here include DVSP, DVXB, DVXF and span 11 categories. AUM among these funds goes as high as $3M.
| Symbol | Name | Category | Risk / Return Rank | YTD Return | AUM | Inception | |
|---|---|---|---|---|---|---|---|
| WEBs SPY Defined Volatility ETF | Large Cap Blend Equities, Volatility Hedged Equity | 50 | 9.88% | 2.11M | Dec 2024 | DVXV vs DVSP | |
| WEBs Materials XLB Defined Volatility ETF | Materials | — | 20.01% | — | Jul 2025 | DVXV vs DVXB | |
| WEBs Financial XLF Defined Volatility ETF | Financials Equities | — | -14.23% | — | Jul 2025 | DVXV vs DVXF | |
| WEBs Energy XLE Defined Volatility ETF | Energy Equities | — | 44.98% | — | Jul 2025 | DVXV vs DVXE | |
| WEBs Consumer Staples XLP Defined Volatility ETF | Consumer Staples Equities | — | 8.96% | — | Jul 2025 | DVXV vs DVXP | |
| WEBs Industrials XLI Defined Volatility ETF | Industrials Equities | — | 15.30% | — | Jul 2025 | DVXV vs DVIN | |
| WEBs QQQ Defined Volatility ETF | Large Cap Growth Equities, Volatility Hedged Equity | 60 | 21.39% | 3.20M | Dec 2024 | DVXV vs DVQQ | |
| WEBs Utilities XLU Defined Volatility ETF | Utilities Equities | — | 2.83% | — | Jul 2025 | DVXV vs DVUT | |
| WEBs Real Estate XLRE Defined Volatility ETF | REIT | — | 6.90% | — | Jul 2025 | DVXV vs DVRE | |
| WEBs Communication Services XLC Defined Volatility... | Communications Equities | — | -13.47% | — | Jul 2025 | DVXV vs DVXC |
Often Compared With DVXV
Investors most often compare DVXV with DVXK, DVXY, BBH. These 11 comparison targets span 3 categories, based on PortfoliosLab usage data.
Compare DVXV with Any Fund or Stock
Compare DVXV with any ETF, mutual fund, or stock using PortfoliosLab's comparison tool.
Pair DVXV with funds that move differently
WEBs Health Care XLV Defined Volatility ETF alternatives help with substitution. Diversifiers are the next step when you want funds with lower historical correlation to DVXV.
Explore DVXV Diversifiers