ALNY vs. ARWR
ALNY (Alnylam Pharmaceuticals, Inc.) and ARWR (Arrowhead Pharmaceuticals, Inc.) are both stocks. Both operate in the Biotechnology industry within the Healthcare sector. Over the past 10 years, ALNY returned 11.28%/yr vs 30.88%/yr for ARWR. Their 0.29 correlation means their historical movements had little consistent relationship.
Performance
ALNY vs. ARWR - Performance Comparison
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Returns By Period
In the year-to-date period, ALNY achieves a -48.32% return, which is significantly lower than ARWR's 27.50% return. Over the past 10 years, ALNY has underperformed ARWR with an annualized return of 11.28%, while ARWR has yielded a comparatively higher 30.88% annualized return.
ALNY
- 1D
- 0.02%
- 1M
- -34.29%
- 6M
- -39.21%
- YTD
- -48.32%
- 1Y
- -48.85%
- 3Y*
- 2.82%
- 5Y*
- 2.81%
- 10Y*
- 11.28%
- ALL TIME*
- 17.20%
ARWR
- 1D
- -3.06%
- 1M
- 0.79%
- 6M
- 22.10%
- YTD
- 27.50%
- 1Y
- 431.39%
- 3Y*
- 35.96%
- 5Y*
- 4.09%
- 10Y*
- 30.88%
- ALL TIME*
- -0.69%
Liquidity Comparison
| Position | Avg. Volume Value (2W) | Avg. Volume Value (1M) | Avg. Volume Value (3M) |
|---|---|---|---|
| $567.18M | $557.43M | $409.61M | |
| $205.45M | $188.79M | $175.31M |
ALNY vs. ARWR - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | |
|---|---|---|---|---|---|---|---|---|---|---|
ALNY Alnylam Pharmaceuticals, Inc. | -48.32% | 68.99% | 22.94% | -19.46% | 40.14% | 30.48% | 12.85% | 57.96% | -42.61% | 239.34% |
ARWR Arrowhead Pharmaceuticals, Inc. | 27.50% | 253.14% | -38.56% | -24.56% | -38.82% | -13.59% | 20.97% | 410.71% | 237.50% | 137.42% |
Correlation
The correlation between ALNY and ARWR is 0.23, which is low. Their historical price movements had little consistent relationship.
| Correlation | |
|---|---|
Correlation (1Y) Focuses on recent behavior, but can change the most. | 0.23 |
Correlation (3Y) Balances recent behavior with more history. | 0.30 |
Correlation (5Y) Shows whether the relationship held over a longer period. | 0.41 |
Correlation (10Y) Provides a long-term view across more market conditions. | 0.39 |
Correlation (All Time) Calculated using the full available price history since Jun 1, 2004 | 0.29 |
The correlation between ALNY and ARWR shifts across timeframes, from 0.23 (1 year) to 0.41 (5 years), reflecting how their relationship changes across market environments.
Fundamentals
ALNY:
$27.44B
ARWR:
$11.92B
ALNY:
$5.88
ARWR:
-$2.16
ALNY:
5.88
ARWR:
19.00
ALNY:
20.98
ARWR:
20.13
ALNY:
$4.80B
ARWR:
$622.01M
ALNY:
$1.88B
ARWR:
$529.27M
ALNY:
$822.65M
ARWR:
-$168.38M
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Return for Risk
ALNY vs. ARWR — Risk / Return Rank
ALNY
ARWR
ALNY vs. ARWR - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for Alnylam Pharmaceuticals, Inc. (ALNY) and Arrowhead Pharmaceuticals, Inc. (ARWR). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| ALNY | ARWR | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | -7.76 | ||
| Sortino ratioReturn per unit of downside risk | -7.12 | ||
| Omega ratioGain probability vs. loss probability | 0.78 | 1.70 | -0.92 |
| Calmar ratioReturn relative to maximum drawdown | -0.82 | 17.83 | -18.65 |
| Martin ratioReturn relative to average drawdown | -1.68 | 51.66 | -53.34 |
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Drawdowns
ALNY vs. ARWR - Drawdown Comparison
The maximum ALNY drawdown since its inception was -83.58%, smaller than the maximum ARWR drawdown of -99.24%. Use the drawdown chart below to compare losses from any high point for ALNY and ARWR.
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Drawdown Indicators
| ALNY | ARWR | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -83.58% | -99.24% | +15.66% |
Max Drawdown (1Y)Largest decline over 1 year | -58.17% | -24.64% | -33.53% |
Max Drawdown (3Y)Largest decline over 3 years | -58.17% | -74.70% | +16.53% |
Max Drawdown (5Y)Largest decline over 5 years | -58.17% | -87.89% | +29.72% |
Max Drawdown (10Y)Largest decline over 10 years | -59.95% | -88.96% | +29.01% |
Current DrawdownCurrent decline from peak | -58.16% | -47.91% | -10.25% |
Average DrawdownAverage peak-to-trough decline | -30.66% | -81.07% | +50.41% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 28.31% | 8.49% | +19.82% |
Volatility
ALNY vs. ARWR - Volatility Comparison
Alnylam Pharmaceuticals, Inc. (ALNY) has a higher volatility of 35.07% compared to Arrowhead Pharmaceuticals, Inc. (ARWR) at 23.10%. This indicates that ALNY's price experiences larger fluctuations and is considered to be riskier than ARWR based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| ALNY | ARWR | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 35.07% | 23.10% | +11.97% |
Volatility (6M)Calculated over the trailing 6-month period | 41.89% | 39.03% | +2.86% |
Volatility (1Y)Calculated over the trailing 1-year period | 47.33% | 65.63% | -18.30% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 50.53% | 64.63% | -14.10% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 54.28% | 74.38% | -20.10% |
Dividends
ALNY vs. ARWR - Dividend Comparison
Neither ALNY nor ARWR has paid dividends to shareholders.
Financials
ALNY vs. ARWR - Financials Comparison
This section allows you to compare key financial metrics between Alnylam Pharmaceuticals, Inc. and Arrowhead Pharmaceuticals, Inc.. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.
Total Revenue: Total amount of money received from sales and other business activities
Frequently Asked Questions
ALNY and ARWR have a correlation of 0.23, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
ALNY has higher volatility (35.07%) compared to ARWR (23.10%). In terms of maximum drawdown, ALNY dropped -83.58% vs ARWR's -99.24%.
ARWR currently has the higher Sharpe Ratio (6.69 vs -1.07), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
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