First Trust NYSE Arca Biotechnology UCITS ETF Class A USD Accumulating (FBTU.L) belongs to the Health & Biotech Equities category. Below you'll find alternative ETFs from the same category, ranked by key criteria, plus funds that investors commonly compare with FBTU.L. Use the tables to find lower-cost options, better risk-adjusted returns, or a closer substitute for your current allocation.
Cheapest Alternatives to FBTU.L
FBTU.L charges 0.60% annually. There are 96 ETFs in the Health & Biotech Equities category with lower expense ratios, going as low as 0.08%.
| Symbol | Name | Expense Ratio | AUM | Inception | |
|---|---|---|---|---|---|
| Fidelity MSCI Health Care Index ETF | 0.08% | 2.85B | Oct 2013 | FBTU.L vs FHLC | |
| State Street Health Care Select Sector SPDR ETF | 0.08% | 38.66B | Dec 1998 | FBTU.L vs XLV | |
| Vanguard Health Care ETF | 0.09% | 18.50B | Jan 2004 | FBTU.L vs VHT | |
| Xtrackers MSCI USA Health Care UCITS ETF 1D | 0.12% | 644.55M | Sep 2017 | FBTU.L vs XSHC.L | |
| Xtrackers MSCI USA Health Care UCITS ETF 1D | 0.12% | — | Sep 2017 | FBTU.L vs XUHC.DE |
Best Risk-Adjusted Alternatives to FBTU.L
FBTU.L has a PortfoliosLab risk / return rank of 52. There are 29 ETFs in the Health & Biotech Equities category with higher risk-adjusted ranks, going as high as 91.
| Symbol | Name | Risk / Return Rank | AUM | Inception | |
|---|---|---|---|---|---|
| Virtus LifeSci Biotech Clinical Trials ETF | 91 | 43.63M | Dec 2014 | FBTU.L vs BBC | |
| iShares U.S. Pharmaceuticals ETF | 81 | 912.87M | May 2006 | FBTU.L vs IHE | |
| SPDR S&P Biotech ETF | 80 | 8.28B | Feb 2006 | FBTU.L vs XBI | |
| First Trust Nasdaq Pharmaceuticals ETF | 77 | 35.04M | Sep 2016 | FBTU.L vs FTXH | |
| ALPS Medical Breakthroughs ETF | 76 | 161.79M | Dec 2014 | FBTU.L vs SBIO |
Top Performing FBTU.L Alternatives (YTD)
FBTU.L is at 8.73% YTD. There are 16 ETFs in the Health & Biotech Equities category with higher YTD returns, going as high as 25.20%.
| Symbol | Name | YTD Return | AUM | Inception | |
|---|---|---|---|---|---|
| ARK Genomic Revolution Multi-Sector ETF | 25.20% | 1.24B | Oct 2014 | FBTU.L vs ARKG | |
| Roundhill UNH WeeklyPay ETF | 22.06% | 4.48M | Dec 2025 | FBTU.L vs UNHW | |
| AdvisorShares Psychedelics ETF | 21.37% | 35.56M | Sep 2021 | FBTU.L vs PSIL | |
| iShares Genomics Immunology and Healthcare Index E... | 14.58% | — | Apr 2022 | FBTU.L vs XDNA.TO | |
| iShares Genomics Immunology and Healthcare ETF Gen... | 14.39% | 163.14M | Jun 2019 | FBTU.L vs IDNA |
Lowest Volatility Alternatives to FBTU.L
FBTU.L has 21.31% 1-year volatility. There are 100 ETFs in the Health & Biotech Equities category with lower 1-year volatility, going as low as 0.00%.
| Symbol | Name | Volatility 1Y | AUM | Inception | |
|---|---|---|---|---|---|
| Principal Healthcare Innovators Index ETF | 0.00% | 16.16M | Aug 2016 | FBTU.L vs BTEC | |
| Amplify Treatments, Testing and Advancements ETF | 0.00% | 9.68M | Jun 2020 | FBTU.L vs GERM | |
| Loncar Cancer Immunotherapy ETF | 0.00% | 12.73M | Oct 2015 | FBTU.L vs CNCR | |
| Horizon Kinetics SPAC Active ETF | 8.80% | 10.01M | Jun 2007 | FBTU.L vs SPAQ | |
| State Street Health Care Select Sector SPDR Premiu... | 11.12% | 14.25M | Jul 2025 | FBTU.L vs XLVI |
Lowest Drawdown Alternatives to FBTU.L
FBTU.L has a 1-year max drawdown of -14.30%. There are 87 ETFs in the Health & Biotech Equities category with shallower 1-year drawdowns, going as shallow as 0.00%.
| Symbol | Name | Max Drawdown 1Y | AUM | Inception | |
|---|---|---|---|---|---|
| Amplify Treatments, Testing and Advancements ETF | 0.00% | 9.68M | Jun 2020 | FBTU.L vs GERM | |
| Horizon Kinetics SPAC Active ETF | -5.30% | 10.01M | Jun 2007 | FBTU.L vs SPAQ | |
| Invesco Nasdaq Biotech UCITS ETF | -6.24% | — | Nov 2014 | FBTU.L vs NBTK.DE | |
| iShares Nasdaq US Biotechnology UCITS ETF | -6.33% | — | Oct 2017 | FBTU.L vs 2B70.DE | |
| iShares Ageing Population UCITS ETF | -6.80% | — | Sep 2016 | FBTU.L vs 2B77.DE |
Other ETFs from First Trust
The 10 most viewed First Trust ETFs shown here include CIBR, GRID, NFTY and span 11 categories. AUM among these funds goes as high as $14B.
Often Compared With FBTU.L
Investors most often compare FBTU.L with IEVL.L, CSKR.L, AINF.L. These 20 comparison targets span 8 categories, based on PortfoliosLab usage data.
Compare FBTU.L with Any Fund or Stock
Compare FBTU.L with any ETF, mutual fund, or stock using PortfoliosLab's comparison tool.
Pair FBTU.L with funds that move differently
First Trust NYSE Arca Biotechnology UCITS ETF Class A USD Accumulating alternatives help with substitution. Diversifiers are the next step when you want funds with lower historical correlation to FBTU.L.
Explore FBTU.L Diversifiers