FBTU.L vs. XDNA.TO
FBTU.L (First Trust NYSE Arca Biotechnology UCITS ETF Class A USD Accumulating) and XDNA.TO (iShares Genomics Immunology and Healthcare Index ETF) are both Health & Biotech Equities funds. Over the past 3 years, FBTU.L returned 13.28%/yr vs 7.44%/yr for XDNA.TO. At a 0.39 correlation, their price movements are largely independent. FBTU.L charges 0.60%/yr vs 0.44%/yr for XDNA.TO.
Performance
FBTU.L vs. XDNA.TO - Performance Comparison
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Different Trading Currencies
FBTU.L is traded in USD, while XDNA.TO is traded in CAD. To make them comparable, the XDNA.TO values have been converted to USD using the latest available exchange rates.
Returns By Period
In the year-to-date period, FBTU.L achieves a 8.73% return, which is significantly lower than XDNA.TO's 13.12% return.
FBTU.L
- 1D
- 4.34%
- 1M
- 9.71%
- YTD
- 8.73%
- 6M
- 6.95%
- 1Y
- 38.25%
- 3Y*
- 13.28%
- 5Y*
- 6.94%
- 10Y*
- —
XDNA.TO
- 1D
- 3.66%
- 1M
- 0.52%
- YTD
- 13.12%
- 6M
- 10.71%
- 1Y
- 43.96%
- 3Y*
- 7.44%
- 5Y*
- —
- 10Y*
- —
FBTU.L vs. XDNA.TO - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | |
|---|---|---|---|---|---|
FBTU.L First Trust NYSE Arca Biotechnology UCITS ETF Class A USD Accumulating | 8.73% | 25.95% | 4.74% | 3.91% | 9.40% |
XDNA.TO iShares Genomics Immunology and Healthcare Index ETF | 13.12% | 17.48% | -2.80% | -5.75% | -17.94% |
Correlation
The correlation between FBTU.L and XDNA.TO is 0.48, which is low. Their price movements are largely independent, making them effective diversification partners.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.48 |
Correlation (3Y) Calculated over the trailing 3-year period | 0.39 |
Correlation (All Time) Calculated using the full available price history since May 4, 2022 | 0.39 |
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Return for Risk
FBTU.L vs. XDNA.TO — Risk / Return Rank
FBTU.L
XDNA.TO
FBTU.L vs. XDNA.TO - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for First Trust NYSE Arca Biotechnology UCITS ETF Class A USD Accumulating (FBTU.L) and iShares Genomics Immunology and Healthcare Index ETF (XDNA.TO). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
| FBTU.L | XDNA.TO | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | +0.03 | ||
| Sortino ratioReturn per unit of downside risk | +0.04 | ||
| Omega ratioGain probability vs. loss probability | 1.30 | 1.31 | 0.00 |
| Calmar ratioReturn relative to maximum drawdown | 2.66 | 4.33 | -1.66 |
| Martin ratioReturn relative to average drawdown | 7.17 | 12.11 | -4.94 |
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month. | |||
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Sharpe Ratios by Period
| FBTU.L | XDNA.TO | Difference | |
|---|---|---|---|
Sharpe Ratio (1Y)Calculated over the trailing 1-year period | 1.79 | 1.75 | +0.03 |
Sharpe Ratio (5Y)Calculated over the trailing 5-year period | 0.33 | — | — |
Sharpe Ratio (All Time)Calculated using the full available price history | 0.27 | -0.00 | +0.27 |
Drawdowns
FBTU.L vs. XDNA.TO - Drawdown Comparison
The maximum FBTU.L drawdown since its inception was -33.73%, smaller than the maximum XDNA.TO drawdown of -49.73%. Use the drawdown chart below to compare losses from any high point for FBTU.L and XDNA.TO.
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Drawdown Indicators
| FBTU.L | XDNA.TO | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -33.73% | -49.73% | +16.00% |
Max Drawdown (1Y)Largest decline over 1 year | -14.30% | -10.21% | -4.09% |
Max Drawdown (3Y)Largest decline over 3 years | -22.47% | -29.71% | +7.24% |
Max Drawdown (5Y)Largest decline over 5 years | -29.97% | — | — |
Current DrawdownCurrent decline from peak | 0.00% | -12.71% | +12.71% |
Average DrawdownAverage peak-to-trough decline | -13.11% | -27.86% | +14.75% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 5.32% | 3.64% | +1.68% |
Volatility
FBTU.L vs. XDNA.TO - Volatility Comparison
The current volatility for First Trust NYSE Arca Biotechnology UCITS ETF Class A USD Accumulating (FBTU.L) is 7.25%, while iShares Genomics Immunology and Healthcare Index ETF (XDNA.TO) has a volatility of 7.76%. This indicates that FBTU.L experiences smaller price fluctuations and is considered to be less risky than XDNA.TO based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| FBTU.L | XDNA.TO | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 7.25% | 7.76% | -0.51% |
Volatility (6M)Calculated over the trailing 6-month period | 16.34% | 18.53% | -2.19% |
Volatility (1Y)Calculated over the trailing 1-year period | 21.31% | 25.18% | -3.87% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 20.91% | 26.48% | -5.57% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 21.38% | 26.48% | -5.10% |
FBTU.L vs. XDNA.TO - Expense Ratio Comparison
FBTU.L has a 0.60% expense ratio, which is higher than XDNA.TO's 0.44% expense ratio.
Dividends
FBTU.L vs. XDNA.TO - Dividend Comparison
FBTU.L has not paid dividends to shareholders, while XDNA.TO's dividend yield for the trailing twelve months is around 0.38%.
| Position | TTM | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
FBTU.L First Trust NYSE Arca Biotechnology UCITS ETF Class A USD Accumulating | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% |
XDNA.TO iShares Genomics Immunology and Healthcare Index ETF | 0.38% | 0.43% | 0.32% | 0.25% | 0.32% |
Frequently Asked Questions
FBTU.L and XDNA.TO have a correlation of 0.48, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
On fees, XDNA.TO is cheaper at 0.44% per year. The better choice depends on whether you care most about return, fees, risk, or income.
XDNA.TO is cheaper with a 0.44% expense ratio, compared with 0.60% for FBTU.L.
They also come from different issuers: First Trust and iShares. Their fees differ too: 0.60% for FBTU.L and 0.44% for XDNA.TO.
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