VanEck Biotech ETF (BBH) belongs to the Health & Biotech Equities category. Below you'll find alternative ETFs from the same category, ranked by key criteria, plus funds that investors commonly compare with BBH. Use the tables to find lower-cost options, better risk-adjusted returns, or a closer substitute for your current allocation.
Cheapest Alternatives to BBH
BBH charges 0.35% annually. There are 8 ETFs in the Health & Biotech Equities category with lower expense ratios, going as low as 0.08%.
| Symbol | Name | Expense Ratio | AUM | Inception | |
|---|---|---|---|---|---|
| Fidelity MSCI Health Care Index ETF | 0.08% | 3.22B | Oct 2013 | BBH vs FHLC | |
| State Street Health Care Select Sector SPDR ETF | 0.08% | 42.10B | Dec 1998 | BBH vs XLV | |
| Vanguard Health Care ETF | 0.09% | 20.40B | Jan 2004 | BBH vs VHT | |
| VanEck Healthcare TruSector ETF | 0.10% | 850.50K | Apr 2026 | BBH vs TRUH | |
| Portfolio Building Block World Pharma and Biotech ... | 0.13% | 933.15M | Nov 2025 | BBH vs PBPH |
Best Risk-Adjusted Alternatives to BBH
BBH has a PortfoliosLab risk / return rank of 56. There are 41 ETFs in the Health & Biotech Equities category with higher risk-adjusted ranks, going as high as 96.
| Symbol | Name | Risk / Return Rank | AUM | Inception | |
|---|---|---|---|---|---|
| Virtus LifeSci Biotech Clinical Trials ETF | 96 | 47.80M | Dec 2014 | BBH vs BBC | |
| iShares U.S. Pharmaceuticals ETF | 95 | 1.65B | May 2006 | BBH vs IHE | |
| First Trust Nasdaq Pharmaceuticals ETF | 95 | 911.09M | Sep 2016 | BBH vs FTXH | |
| ALPS Medical Breakthroughs ETF | 95 | 201.57M | Dec 2014 | BBH vs SBIO | |
| Invesco Dynamic Pharmaceuticals ETF | 94 | 472.10M | Jun 2005 | BBH vs PJP |
Top Performing BBH Alternatives (YTD)
BBH is at 7.93% YTD. There are 30 ETFs in the Health & Biotech Equities category with higher YTD returns, going as high as 36.76%.
| Symbol | Name | YTD Return | AUM | Inception | |
|---|---|---|---|---|---|
| ARK Genomic Revolution Multi-Sector ETF | 36.76% | 1.73B | Oct 2014 | BBH vs ARKG | |
| AdvisorShares Psychedelics ETF | 36.69% | 48.53M | Sep 2021 | BBH vs PSIL | |
| Roundhill UNH WeeklyPay ETF | 28.89% | 7.27M | Dec 2025 | BBH vs UNHW | |
| Virtus LifeSci Biotech Clinical Trials ETF | 27.03% | 47.80M | Dec 2014 | BBH vs BBC | |
| SPDR S&P Health Care Services ETF | 25.67% | 206.72M | Sep 2011 | BBH vs XHS |
Lowest Volatility Alternatives to BBH
BBH has 19.49% 1-year volatility. There are 31 ETFs in the Health & Biotech Equities category with lower 1-year volatility, going as low as 0.00%.
| Symbol | Name | Volatility 1Y | AUM | Inception | |
|---|---|---|---|---|---|
| Loncar Cancer Immunotherapy ETF | 0.00% | 12.73M | Oct 2015 | BBH vs CNCR | |
| Amplify Treatments, Testing and Advancements ETF | 0.00% | 9.68M | Jun 2020 | BBH vs GERM | |
| Horizon Kinetics SPAC Active ETF | 8.66% | 10.09M | Jun 2007 | BBH vs SPAQ | |
| State Street Health Care Select Sector SPDR Premiu... | 10.75% | 21.55M | Jul 2025 | BBH vs XLVI | |
| Milliman Healthcare Inflation Plus ETF | 10.92% | 982.35K | Apr 2026 | BBH vs MHIP |
Lowest Drawdown Alternatives to BBH
BBH has a 1-year max drawdown of -10.55%. There are 17 ETFs in the Health & Biotech Equities category with shallower 1-year drawdowns, going as shallow as 0.00%.
| Symbol | Name | Max Drawdown 1Y | AUM | Inception | |
|---|---|---|---|---|---|
| Amplify Treatments, Testing and Advancements ETF | 0.00% | 9.68M | Jun 2020 | BBH vs GERM | |
| Horizon Kinetics SPAC Active ETF | -4.20% | 10.09M | Jun 2007 | BBH vs SPAQ | |
| First Trust Nasdaq Pharmaceuticals ETF | -7.47% | 911.09M | Sep 2016 | BBH vs FTXH | |
| State Street Health Care Select Sector SPDR Premiu... | -8.14% | 21.55M | Jul 2025 | BBH vs XLVI | |
| Invesco Nasdaq Biotechnology ETF | -8.34% | 75.06M | Jun 2021 | BBH vs IBBQ |
Other ETFs from VanEck
The 10 most viewed VanEck ETFs shown here include SMH, GDX, NLR and span 13 categories. AUM among these funds goes as high as $68B.
| Symbol | Name | Category | Risk / Return Rank | YTD Return | AUM | Inception | |
|---|---|---|---|---|---|---|---|
| VanEck Semiconductor ETF | Semiconductors, Technology Equities | 88 | 51.46% | 68.10B | Dec 2011 | BBH vs SMH | |
| VanEck Gold Miners ETF | Gold, Precious Metals | 36 | -11.33% | 22.65B | May 2006 | BBH vs GDX | |
| VanEck Uranium and Nuclear ETF | Uranium, Alternative Energy Equities, Energy Equities | 13 | -10.20% | 3.81B | Aug 2007 | BBH vs NLR | |
| VanEck Junior Gold Miners ETF | Gold, Precious Metals | 38 | -13.28% | 6.89B | Nov 2009 | BBH vs GDXJ | |
| VanEck Morningstar Wide Moat ETF | Large Cap Blend Equities | 41 | 5.78% | 11.80B | Apr 2012 | BBH vs MOAT | |
| VanEck Fabless Semiconductor ETF | Semiconductors, Technology Equities | 68 | 45.86% | 249.42M | Aug 2024 | BBH vs SMHX | |
| VanEck Rare Earth and Strategic Metals ETF | Rare Earth & Strategic Metals | 33 | -8.51% | 1.90B | Oct 2010 | BBH vs REMX | |
| VanEck BDC Income ETF | Financials Equities | 5 | -4.84% | 1.57B | Feb 2013 | BBH vs BIZD | |
| VanEck Bitcoin Trust | Cryptocurrency | 2 | -27.01% | 1.05B | Jan 2024 | BBH vs HODL | |
| VanEck IG Floating Rate ETF | Corporate Bonds, Ultrashort Bond | 99 | 2.70% | 3.00B | Apr 2011 | BBH vs FLTR |
Often Compared With BBH
Investors most often compare BBH with XBI, IBB, FBT. These 20 comparison targets span 6 categories, based on PortfoliosLab usage data.
Compare BBH with Any Fund or Stock
Compare BBH with any ETF, mutual fund, or stock using PortfoliosLab's comparison tool.
Pair BBH with funds that move differently
VanEck Biotech ETF alternatives help with substitution. Diversifiers are the next step when you want funds with lower historical correlation to BBH.
Explore BBH Diversifiers