VRTX vs. KAP.IL

Last updated Jun 13, 2026

VRTX (Vertex Pharmaceuticals Incorporated) and KAP.IL (JSC National Atomic Company Kazatomprom) are both stocks. VRTX operates in Biotechnology (Healthcare), while KAP.IL operates in Uranium (Energy). Over the past 5 years, VRTX returned 18.18%/yr vs 24.26%/yr for KAP.IL. At a 0.04 correlation, their price movements are largely independent.

Performance

VRTX vs. KAP.IL - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Vertex Pharmaceuticals Incorporated (VRTX) and JSC National Atomic Company Kazatomprom (KAP.IL). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, VRTX achieves a -1.86% return, which is significantly lower than KAP.IL's 24.37% return.

VRTX

• 1D: -0.03%
• 1M: -1.22%
• YTD: -1.86%
• 6M: -1.57%
• 1Y: -2.31%
• 3Y*: 9.16%
• 5Y*: 18.18%
• 10Y*: 17.15%

KAP.IL

• 1D: -0.14%
• 1M: -0.00%
• YTD: 24.37%
• 6M: 19.24%
• 1Y: 78.29%
• 3Y*: 43.43%
• 5Y*: 24.26%
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

VRTX vs. KAP.IL - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018
VRTX Vertex Pharmaceuticals Incorporated	-1.86%	12.58%	-1.03%	40.90%	31.50%	-7.08%	7.94%	32.13%	-4.13%
KAP.IL JSC National Atomic Company Kazatomprom	24.37%	56.07%	-1.79%	55.12%	-17.26%	115.04%	48.04%	1.25%	13.42%

Correlation

The correlation between VRTX and KAP.IL is 0.02, meaning there is essentially no relationship between their price movements. Each responds to its own set of market drivers, making them strong candidates for combining in a diversified portfolio.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.02
Correlation (3Y) Calculated over the trailing 3-year period	0.03
Correlation (5Y) Calculated over the trailing 5-year period	0.04
Correlation (All Time) Calculated using the full available price history since Nov 13, 2018	0.04

Return for Risk

VRTX vs. KAP.IL — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

VRTX

VRTX Risk / Return Rank: 37
VRTX Sharpe Ratio Rank: 39
VRTX Sortino Ratio Rank: 34
VRTX Omega Ratio Rank: 35
VRTX Calmar Ratio Rank: 38
VRTX Martin Ratio Rank: 37

KAP.IL

KAP.IL Risk / Return Rank: 83
KAP.IL Sharpe Ratio Rank: 85
KAP.IL Sortino Ratio Rank: 81
KAP.IL Omega Ratio Rank: 80
KAP.IL Calmar Ratio Rank: 84
KAP.IL Martin Ratio Rank: 86

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

VRTX vs. KAP.IL - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Vertex Pharmaceuticals Incorporated (VRTX) and JSC National Atomic Company Kazatomprom (KAP.IL). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.

	VRTX	KAP.IL	Difference
Sharpe ratio: Return per unit of total volatility	-0.10	1.61	-1.71
Sortino ratio: Return per unit of downside risk	0.10	2.25	-2.15
Omega ratio: Gain probability vs. loss probability	1.02	1.29	-0.27
Calmar ratio: Return relative to maximum drawdown	-0.14	2.96	-3.10
Martin ratio: Return relative to average drawdown	-0.29	8.64	-8.94

VRTX vs. KAP.IL - Sharpe Ratio Comparison

The current VRTX Sharpe Ratio is -0.10, which is lower than the KAP.IL Sharpe Ratio of 1.61. The chart below compares the historical Sharpe Ratios of VRTX and KAP.IL, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Drawdowns

VRTX vs. KAP.IL - Drawdown Comparison

The maximum VRTX drawdown since its inception was -91.77%, which is greater than KAP.IL's maximum drawdown of -49.67%. Use the drawdown chart below to compare losses from any high point for VRTX and KAP.IL.

Drawdown Indicators

	VRTX	KAP.IL	Difference
Max Drawdown Largest peak-to-trough decline	-91.77%	-49.67%	-42.10%
Max Drawdown (1Y) Largest decline over 1 year	-23.56%	-25.44%	+1.88%
Max Drawdown (3Y) Largest decline over 3 years	-29.07%	-33.25%	+4.18%
Max Drawdown (5Y) Largest decline over 5 years	-29.07%	-49.67%	+20.60%
Max Drawdown (10Y) Largest decline over 10 years	-41.60%	—	—
Current Drawdown Current decline from peak	-13.90%	-23.90%	+10.00%
Average Drawdown Average peak-to-trough decline	-37.73%	-14.97%	-22.76%
Ulcer Index Depth and duration of drawdowns from previous peaks	11.30%	8.73%	+2.57%

Volatility

VRTX vs. KAP.IL - Volatility Comparison

The current volatility for Vertex Pharmaceuticals Incorporated (VRTX) is 7.47%, while JSC National Atomic Company Kazatomprom (KAP.IL) has a volatility of 10.50%. This indicates that VRTX experiences smaller price fluctuations and is considered to be less risky than KAP.IL based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	VRTX	KAP.IL	Difference
Volatility (1M) Calculated over the trailing 1-month period	7.47%	10.50%	-3.03%
Volatility (6M) Calculated over the trailing 6-month period	20.71%	37.79%	-17.08%
Volatility (1Y) Calculated over the trailing 1-year period	34.13%	46.83%	-12.70%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	28.53%	47.34%	-18.81%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	32.82%	42.88%	-10.06%

Dividends

VRTX vs. KAP.IL - Dividend Comparison

VRTX has not paid dividends to shareholders, while KAP.IL's dividend yield for the trailing twelve months is around 3.38%.

Position	TTM	2025	2024	2023	2022	2021	2020	2019
KAP.IL JSC National Atomic Company Kazatomprom	3.38%	4.20%	6.85%	4.26%	6.94%	3.69%	5.15%	6.23%
VRTX Vertex Pharmaceuticals Incorporated	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%

Financials

Frequently Asked Questions

Can I hold both VRTX and KAP.IL in my portfolio?

VRTX and KAP.IL have a correlation of 0.02, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.