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VRTX vs. REGN
Performance
Risk-Adjusted Performance
Dividends
Drawdowns
Volatility
Financials

Correlation

The correlation between VRTX and REGN is 0.39, which is considered to be low. This implies their price changes are not closely related. A low correlation is generally favorable for portfolio diversification, as it helps to reduce overall risk by spreading it across multiple assets with different performance patterns.


-0.50.00.51.0
Correlation: 0.4

Performance

VRTX vs. REGN - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Vertex Pharmaceuticals Incorporated (VRTX) and Regeneron Pharmaceuticals, Inc. (REGN). The values are adjusted to include any dividend payments, if applicable.

2,000.00%4,000.00%6,000.00%8,000.00%10,000.00%NovemberDecember2025FebruaryMarchApril
2,635.94%
5,758.86%
VRTX
REGN

Key characteristics

Sharpe Ratio

VRTX:

0.89

REGN:

-1.17

Sortino Ratio

VRTX:

1.24

REGN:

-1.60

Omega Ratio

VRTX:

1.18

REGN:

0.80

Calmar Ratio

VRTX:

1.00

REGN:

-0.61

Martin Ratio

VRTX:

2.70

REGN:

-1.12

Ulcer Index

VRTX:

8.57%

REGN:

29.62%

Daily Std Dev

VRTX:

26.16%

REGN:

28.44%

Max Drawdown

VRTX:

-91.77%

REGN:

-91.81%

Current Drawdown

VRTX:

-4.70%

REGN:

-50.03%

Fundamentals

Market Cap

VRTX:

$126.59B

REGN:

$64.01B

EPS

VRTX:

-$2.07

REGN:

$38.50

PEG Ratio

VRTX:

1.35

REGN:

0.94

PS Ratio

VRTX:

11.49

REGN:

4.51

PB Ratio

VRTX:

7.71

REGN:

2.19

Total Revenue (TTM)

VRTX:

$8.32B

REGN:

$11.06B

Gross Profit (TTM)

VRTX:

$7.13B

REGN:

$9.40B

EBITDA (TTM)

VRTX:

-$856.70M

REGN:

$3.94B

Returns By Period

In the year-to-date period, VRTX achieves a 22.29% return, which is significantly higher than REGN's -15.69% return. Over the past 10 years, VRTX has outperformed REGN with an annualized return of 14.48%, while REGN has yielded a comparatively lower 2.41% annualized return.


VRTX

YTD

22.29%

1M

-3.26%

6M

4.36%

1Y

22.88%

5Y*

12.83%

10Y*

14.48%

REGN

YTD

-15.69%

1M

-5.42%

6M

-35.35%

1Y

-33.76%

5Y*

1.19%

10Y*

2.41%

*Annualized

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Risk-Adjusted Performance

VRTX vs. REGN — Risk-Adjusted Performance Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

VRTX
The Risk-Adjusted Performance Rank of VRTX is 7878
Overall Rank
The Sharpe Ratio Rank of VRTX is 8282
Sharpe Ratio Rank
The Sortino Ratio Rank of VRTX is 7272
Sortino Ratio Rank
The Omega Ratio Rank of VRTX is 7474
Omega Ratio Rank
The Calmar Ratio Rank of VRTX is 8585
Calmar Ratio Rank
The Martin Ratio Rank of VRTX is 7878
Martin Ratio Rank

REGN
The Risk-Adjusted Performance Rank of REGN is 1010
Overall Rank
The Sharpe Ratio Rank of REGN is 22
Sharpe Ratio Rank
The Sortino Ratio Rank of REGN is 55
Sortino Ratio Rank
The Omega Ratio Rank of REGN is 77
Omega Ratio Rank
The Calmar Ratio Rank of REGN is 1414
Calmar Ratio Rank
The Martin Ratio Rank of REGN is 2424
Martin Ratio Rank
The risk-adjusted ranks indicate the investment's position relative to the market. A rank closer to 100 signifies top-performing investments, while a rank closer to 0 might suggest underperformance, based on the selected ratio. The values are calculated based on the past 12 months of returns.

VRTX vs. REGN - Risk-Adjusted Performance Comparison

This table presents a comparison of risk-adjusted performance metrics for Vertex Pharmaceuticals Incorporated (VRTX) and Regeneron Pharmaceuticals, Inc. (REGN). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.


The chart of Sharpe ratio for VRTX, currently valued at 0.89, compared to the broader market-2.00-1.000.001.002.003.00
VRTX: 0.89
REGN: -1.17
The chart of Sortino ratio for VRTX, currently valued at 1.24, compared to the broader market-6.00-4.00-2.000.002.004.00
VRTX: 1.24
REGN: -1.60
The chart of Omega ratio for VRTX, currently valued at 1.18, compared to the broader market0.501.001.502.00
VRTX: 1.18
REGN: 0.80
The chart of Calmar ratio for VRTX, currently valued at 1.00, compared to the broader market0.001.002.003.004.005.00
VRTX: 1.00
REGN: -0.61
The chart of Martin ratio for VRTX, currently valued at 2.70, compared to the broader market-10.00-5.000.005.0010.0015.0020.00
VRTX: 2.70
REGN: -1.12

The current VRTX Sharpe Ratio is 0.89, which is higher than the REGN Sharpe Ratio of -1.17. The chart below compares the historical Sharpe Ratios of VRTX and REGN, offering insights into how both investments have performed under varying market conditions. These values are calculated using daily returns over the previous 12 months.


Rolling 12-month Sharpe Ratio-2.00-1.000.001.002.00NovemberDecember2025FebruaryMarchApril
0.89
-1.17
VRTX
REGN

Dividends

VRTX vs. REGN - Dividend Comparison

VRTX has not paid dividends to shareholders, while REGN's dividend yield for the trailing twelve months is around 0.15%.


Drawdowns

VRTX vs. REGN - Drawdown Comparison

The maximum VRTX drawdown since its inception was -91.77%, roughly equal to the maximum REGN drawdown of -91.81%. Use the drawdown chart below to compare losses from any high point for VRTX and REGN. For additional features, visit the drawdowns tool.


-50.00%-40.00%-30.00%-20.00%-10.00%0.00%NovemberDecember2025FebruaryMarchApril
-4.70%
-50.03%
VRTX
REGN

Volatility

VRTX vs. REGN - Volatility Comparison

The current volatility for Vertex Pharmaceuticals Incorporated (VRTX) is 7.37%, while Regeneron Pharmaceuticals, Inc. (REGN) has a volatility of 12.61%. This indicates that VRTX experiences smaller price fluctuations and is considered to be less risky than REGN based on this measure. The chart below showcases a comparison of their rolling one-month volatility.


4.00%6.00%8.00%10.00%12.00%14.00%NovemberDecember2025FebruaryMarchApril
7.37%
12.61%
VRTX
REGN

Financials

VRTX vs. REGN - Financials Comparison

This section allows you to compare key financial metrics between Vertex Pharmaceuticals Incorporated and Regeneron Pharmaceuticals, Inc.. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.


Quarterly
Annual

Total Revenue: Total amount of money received from sales and other business activities


Values in USD except per share items