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VRTX vs. REGN
Performance
Risk-Adjusted Performance
Dividends
Drawdowns
Volatility
Financials

Correlation

The correlation between VRTX and REGN is 0.39, which is considered to be low. This implies their price changes are not closely related. A low correlation is generally favorable for portfolio diversification, as it helps to reduce overall risk by spreading it across multiple assets with different performance patterns.


Performance

VRTX vs. REGN - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Vertex Pharmaceuticals Incorporated (VRTX) and Regeneron Pharmaceuticals, Inc. (REGN). The values are adjusted to include any dividend payments, if applicable.

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Key characteristics

Sharpe Ratio

VRTX:

-0.03

REGN:

-1.26

Sortino Ratio

VRTX:

0.23

REGN:

-1.83

Omega Ratio

VRTX:

1.03

REGN:

0.77

Calmar Ratio

VRTX:

0.04

REGN:

-0.71

Martin Ratio

VRTX:

0.11

REGN:

-1.24

Ulcer Index

VRTX:

9.06%

REGN:

32.21%

Daily Std Dev

VRTX:

28.64%

REGN:

32.01%

Max Drawdown

VRTX:

-91.77%

REGN:

-91.81%

Current Drawdown

VRTX:

-15.94%

REGN:

-51.26%

Fundamentals

Market Cap

VRTX:

$108.15B

REGN:

$61.69B

EPS

VRTX:

-$3.80

REGN:

$39.33

PEG Ratio

VRTX:

2.57

REGN:

1.24

PS Ratio

VRTX:

9.74

REGN:

4.38

PB Ratio

VRTX:

6.72

REGN:

2.11

Total Revenue (TTM)

VRTX:

$11.09B

REGN:

$14.09B

Gross Profit (TTM)

VRTX:

$9.54B

REGN:

$11.96B

EBITDA (TTM)

VRTX:

-$228.00M

REGN:

$4.98B

Returns By Period

In the year-to-date period, VRTX achieves a 7.87% return, which is significantly higher than REGN's -17.77% return. Over the past 10 years, VRTX has outperformed REGN with an annualized return of 13.09%, while REGN has yielded a comparatively lower 1.67% annualized return.


VRTX

YTD

7.87%

1M

-13.21%

6M

-10.24%

1Y

-0.71%

5Y*

8.54%

10Y*

13.09%

REGN

YTD

-17.77%

1M

4.85%

6M

-25.15%

1Y

-40.12%

5Y*

0.31%

10Y*

1.67%

*Annualized

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Risk-Adjusted Performance

VRTX vs. REGN — Risk-Adjusted Performance Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

VRTX
The Risk-Adjusted Performance Rank of VRTX is 4848
Overall Rank
The Sharpe Ratio Rank of VRTX is 5050
Sharpe Ratio Rank
The Sortino Ratio Rank of VRTX is 4242
Sortino Ratio Rank
The Omega Ratio Rank of VRTX is 4343
Omega Ratio Rank
The Calmar Ratio Rank of VRTX is 5353
Calmar Ratio Rank
The Martin Ratio Rank of VRTX is 5252
Martin Ratio Rank

REGN
The Risk-Adjusted Performance Rank of REGN is 66
Overall Rank
The Sharpe Ratio Rank of REGN is 11
Sharpe Ratio Rank
The Sortino Ratio Rank of REGN is 33
Sortino Ratio Rank
The Omega Ratio Rank of REGN is 44
Omega Ratio Rank
The Calmar Ratio Rank of REGN is 88
Calmar Ratio Rank
The Martin Ratio Rank of REGN is 1515
Martin Ratio Rank
The risk-adjusted ranks indicate the investment's position relative to the market. A rank closer to 100 signifies top-performing investments, while a rank closer to 0 might suggest underperformance, based on the selected ratio. The values are calculated based on the past 12 months of returns.

VRTX vs. REGN - Risk-Adjusted Performance Comparison

This table presents a comparison of risk-adjusted performance metrics for Vertex Pharmaceuticals Incorporated (VRTX) and Regeneron Pharmaceuticals, Inc. (REGN). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.


The current VRTX Sharpe Ratio is -0.03, which is higher than the REGN Sharpe Ratio of -1.26. The chart below compares the historical Sharpe Ratios of VRTX and REGN, offering insights into how both investments have performed under varying market conditions. These values are calculated using daily returns over the previous 12 months.


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Dividends

VRTX vs. REGN - Dividend Comparison

VRTX has not paid dividends to shareholders, while REGN's dividend yield for the trailing twelve months is around 0.15%.


Drawdowns

VRTX vs. REGN - Drawdown Comparison

The maximum VRTX drawdown since its inception was -91.77%, roughly equal to the maximum REGN drawdown of -91.81%. Use the drawdown chart below to compare losses from any high point for VRTX and REGN. For additional features, visit the drawdowns tool.


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Volatility

VRTX vs. REGN - Volatility Comparison

The current volatility for Vertex Pharmaceuticals Incorporated (VRTX) is 13.64%, while Regeneron Pharmaceuticals, Inc. (REGN) has a volatility of 17.09%. This indicates that VRTX experiences smaller price fluctuations and is considered to be less risky than REGN based on this measure. The chart below showcases a comparison of their rolling one-month volatility.


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Financials

VRTX vs. REGN - Financials Comparison

This section allows you to compare key financial metrics between Vertex Pharmaceuticals Incorporated and Regeneron Pharmaceuticals, Inc.. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.


Quarterly
Annual

Total Revenue: Total amount of money received from sales and other business activities


2.00B3.00B4.00B5.00B20212022202320242025
2.77B
3.03B
(VRTX) Total Revenue
(REGN) Total Revenue
Values in USD except per share items

VRTX vs. REGN - Profitability Comparison

The chart below illustrates the profitability comparison between Vertex Pharmaceuticals Incorporated and Regeneron Pharmaceuticals, Inc. over time, highlighting three key metrics: Gross Profit Margin, Operating Margin, and Net Profit Margin.

Gross Margin
Operating Margin
Net Margin
Quarterly
Annual

80.0%82.0%84.0%86.0%88.0%90.0%92.0%94.0%20212022202320242025
86.9%
84.7%
(VRTX) Gross Margin
(REGN) Gross Margin
VRTX - Gross Margin

Gross margin is calculated as gross profit divided by revenue. For the three months ending on May 2025, Vertex Pharmaceuticals Incorporated reported a gross profit of 2.41B and revenue of 2.77B. Therefore, the gross margin over that period was 86.9%.

REGN - Gross Margin

Gross margin is calculated as gross profit divided by revenue. For the three months ending on May 2025, Regeneron Pharmaceuticals, Inc. reported a gross profit of 2.56B and revenue of 3.03B. Therefore, the gross margin over that period was 84.7%.

VRTX - Operating Margin

Operating margin is calculated as operating income divided by revenue. For the three months ending on May 2025, Vertex Pharmaceuticals Incorporated reported an operating income of 630.10M and revenue of 2.77B, resulting in an operating margin of 22.8%.

REGN - Operating Margin

Operating margin is calculated as operating income divided by revenue. For the three months ending on May 2025, Regeneron Pharmaceuticals, Inc. reported an operating income of 591.70M and revenue of 3.03B, resulting in an operating margin of 19.5%.

VRTX - Net Margin

Net margin is calculated as net income divided by revenue. For the three months ending on May 2025, Vertex Pharmaceuticals Incorporated reported a net income of 646.30M and revenue of 2.77B, resulting in a net margin of 23.3%.

REGN - Net Margin

Net margin is calculated as net income divided by revenue. For the three months ending on May 2025, Regeneron Pharmaceuticals, Inc. reported a net income of 808.70M and revenue of 3.03B, resulting in a net margin of 26.7%.