VRTX vs. SHEL
VRTX (Vertex Pharmaceuticals Incorporated) and SHEL (Shell plc) are both stocks. VRTX operates in Biotechnology (Healthcare), while SHEL operates in Oil & Gas Integrated (Energy). Over the past 10 years, VRTX returned 16.29%/yr vs 10.58%/yr for SHEL. At a 0.20 correlation, their price movements are largely independent.
Performance
VRTX vs. SHEL - Performance Comparison
Loading charts...
Returns By Period
In the year-to-date period, VRTX achieves a -6.24% return, which is significantly lower than SHEL's 20.34% return. Over the past 10 years, VRTX has outperformed SHEL with an annualized return of 16.29%, while SHEL has yielded a comparatively lower 10.58% annualized return.
VRTX
- 1D
- -3.04%
- 1M
- 0.28%
- YTD
- -6.24%
- 6M
- -1.86%
- 1Y
- -4.57%
- 3Y*
- 8.39%
- 5Y*
- 15.02%
- 10Y*
- 16.29%
SHEL
- 1D
- 1.65%
- 1M
- -1.54%
- YTD
- 20.34%
- 6M
- 19.56%
- 1Y
- 33.66%
- 3Y*
- 18.89%
- 5Y*
- 22.78%
- 10Y*
- 10.58%
VRTX vs. SHEL - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | |
|---|---|---|---|---|---|---|---|---|---|---|
VRTX Vertex Pharmaceuticals Incorporated | -6.24% | 12.58% | -1.03% | 40.90% | 31.50% | -7.08% | 7.94% | 32.13% | 10.58% | 103.42% |
SHEL Shell plc | 20.34% | 22.16% | -0.87% | 20.19% | 36.18% | 34.27% | -41.08% | 6.38% | -7.23% | 21.67% |
Correlation
The correlation between VRTX and SHEL is -0.04, meaning there is essentially no relationship between their price movements. Each responds to its own set of market drivers, making them strong candidates for combining in a diversified portfolio.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | -0.04 |
Correlation (3Y) Calculated over the trailing 3-year period | 0.05 |
Correlation (5Y) Calculated over the trailing 5-year period | 0.09 |
Correlation (10Y) Calculated over the trailing 10-year period | 0.12 |
Correlation (All Time) Calculated using the full available price history since Jul 22, 2005 | 0.20 |
The correlation between VRTX and SHEL shifts across timeframes, from -0.04 (1 year) to 0.20 (all time), reflecting how their relationship changes across market environments.
Fundamentals
VRTX:
$108.95B
SHEL:
$247.60B
VRTX:
$16.87
SHEL:
$6.39
VRTX:
25.20
SHEL:
13.58
VRTX:
2.10
SHEL:
0.68
VRTX:
8.92
SHEL:
0.95
VRTX:
4.11
SHEL:
1.43
VRTX:
$12.26B
SHEL:
$266.82B
VRTX:
$10.57B
SHEL:
$41.65B
VRTX:
$5.19B
SHEL:
$57.44B
Compare stocks, funds, or ETFs
Search for stocks, ETFs, and funds for a quick comparison or use the comparison tool for more options.
Return for Risk
VRTX vs. SHEL — Risk / Return Rank
VRTX
SHEL
VRTX vs. SHEL - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for Vertex Pharmaceuticals Incorporated (VRTX) and Shell plc (SHEL). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
| VRTX | SHEL | Difference | |
|---|---|---|---|
Sharpe ratioReturn per unit of total volatility | -0.14 | 1.61 | -1.74 |
Sortino ratioReturn per unit of downside risk | 0.05 | 2.16 | -2.11 |
Omega ratioGain probability vs. loss probability | 1.01 | 1.27 | -0.27 |
Calmar ratioReturn relative to maximum drawdown | -0.16 | 3.34 | -3.51 |
Martin ratioReturn relative to average drawdown | -0.35 | 9.67 | -10.02 |
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month. | |||
Loading charts...
Sharpe Ratios by Period
| VRTX | SHEL | Difference | |
|---|---|---|---|
Sharpe Ratio (1Y)Calculated over the trailing 1-year period | -0.14 | 1.61 | -1.74 |
Sharpe Ratio (5Y)Calculated over the trailing 5-year period | 0.52 | 0.91 | -0.39 |
Sharpe Ratio (10Y)Calculated over the trailing 10-year period | 0.50 | 0.34 | +0.15 |
Sharpe Ratio (All Time)Calculated using the full available price history | 0.25 | 0.22 | +0.03 |
Drawdowns
VRTX vs. SHEL - Drawdown Comparison
The maximum VRTX drawdown since its inception was -91.77%, which is greater than SHEL's maximum drawdown of -71.57%. Use the drawdown chart below to compare losses from any high point for VRTX and SHEL.
Loading charts...
Drawdown Indicators
| VRTX | SHEL | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -91.77% | -71.57% | -20.20% |
Max Drawdown (1Y)Largest decline over 1 year | -23.56% | -10.81% | -12.75% |
Max Drawdown (3Y)Largest decline over 3 years | -29.07% | -18.47% | -10.60% |
Max Drawdown (5Y)Largest decline over 5 years | -29.07% | -25.04% | -4.03% |
Max Drawdown (10Y)Largest decline over 10 years | -41.60% | -71.57% | +29.97% |
Current DrawdownCurrent decline from peak | -17.74% | -6.95% | -10.79% |
Average DrawdownAverage peak-to-trough decline | -37.70% | -16.75% | -20.95% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 11.11% | 3.74% | +7.37% |
Volatility
VRTX vs. SHEL - Volatility Comparison
Vertex Pharmaceuticals Incorporated (VRTX) and Shell plc (SHEL) have volatilities of 7.13% and 7.28%, respectively, indicating that both stocks experience similar levels of price fluctuations. This suggests that the risk associated with both stocks, as measured by volatility, is nearly the same. The chart below showcases a comparison of their rolling one-month volatility.
Loading charts...
Volatility by Period
| VRTX | SHEL | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 7.13% | 7.28% | -0.15% |
Volatility (6M)Calculated over the trailing 6-month period | 21.76% | 17.47% | +4.29% |
Volatility (1Y)Calculated over the trailing 1-year period | 33.88% | 21.10% | +12.78% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 28.90% | 25.20% | +3.70% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 32.83% | 30.87% | +1.96% |
Dividends
VRTX vs. SHEL - Dividend Comparison
VRTX has not paid dividends to shareholders, while SHEL's dividend yield for the trailing twelve months is around 3.41%.
| Position | TTM | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
SHEL Shell plc | 3.41% | 3.90% | 4.39% | 3.76% | 3.48% | 3.78% | 5.69% | 6.27% | 6.27% | 2.75% | 6.49% | 8.17% |
VRTX Vertex Pharmaceuticals Incorporated | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% |
Financials
VRTX vs. SHEL - Financials Comparison
This section allows you to compare key financial metrics between Vertex Pharmaceuticals Incorporated and Shell plc. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.
Total Revenue: Total amount of money received from sales and other business activities
VRTX vs. SHEL - Profitability Comparison
VRTX - Gross Margin
Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jun 2026, Vertex Pharmaceuticals Incorporated reported a gross profit of 2.59B and revenue of 2.99B. Therefore, the gross margin over that period was 86.9%.
SHEL - Gross Margin
Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jun 2026, Shell plc reported a gross profit of 13.31B and revenue of 69.57B. Therefore, the gross margin over that period was 19.1%.
VRTX - Operating Margin
Operating margin is calculated as operating income divided by revenue. For the three months ending on Jun 2026, Vertex Pharmaceuticals Incorporated reported an operating income of 1.14B and revenue of 2.99B, resulting in an operating margin of 38.1%.
SHEL - Operating Margin
Operating margin is calculated as operating income divided by revenue. For the three months ending on Jun 2026, Shell plc reported an operating income of 10.35B and revenue of 69.57B, resulting in an operating margin of 14.9%.
VRTX - Net Margin
Net margin is calculated as net income divided by revenue. For the three months ending on Jun 2026, Vertex Pharmaceuticals Incorporated reported a net income of 1.03B and revenue of 2.99B, resulting in a net margin of 34.5%.
SHEL - Net Margin
Net margin is calculated as net income divided by revenue. For the three months ending on Jun 2026, Shell plc reported a net income of 5.68B and revenue of 69.57B, resulting in a net margin of 8.2%.
Frequently Asked Questions
VRTX and SHEL have a correlation of -0.04, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
SHEL has higher volatility (7.28%) compared to VRTX (7.13%). In terms of maximum drawdown, VRTX dropped -91.77% vs SHEL's -71.57%.
SHEL currently has the higher Sharpe Ratio (1.61 vs -0.14), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
Find the right allocation for VRTX and SHEL
Add both to a portfolio and optimize allocations for your target — whether that's maximizing returns, minimizing drawdowns, or balancing risk across holdings.
Open Portfolio Optimizer