- ISIN
- US92532F1003
- CUSIP
- 92532F100
- Sector
- Healthcare
- Industry
- Biotechnology
- IPO Date
- Jul 24, 1991
Highlights
- Market Cap
- $119.64B
- Enterprise Value
- $114.38B
- EPS (TTM)
- $16.87
- PE Ratio
- 27.68
- PEG Ratio
- 2.30
- Total Revenue (TTM)
- $12.26B
- Gross Profit (TTM)
- $10.57B
- EBITDA (TTM)
- $5.19B
- Year Range
- $362.50 - $507.92
- Target Price
- $552.27
- ROA (TTM)
- 16.38%
- ROE (TTM)
- 16.38%
Share Price Chart
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Performance
VRTX Performance Chart
Vertex Pharmaceuticals Incorporated (VRTX) is up 3.0% since the beginning of the year. At $467 per share, VRTX is trading 8.1% below its 52-week high of $508. Investors who bought $1,000 worth of VRTX shares 5 years ago would now be looking at an investment worth $2,489.
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Returns By Period
Vertex Pharmaceuticals Incorporated (VRTX) has returned 2.96% so far this year and 5.88% over the past 12 months. Looking at the last ten years, VRTX has achieved an annualized return of 19.01%, outperforming the S&P 500 Index benchmark, which averaged 13.88% per year.
Vertex Pharmaceuticals Incorporated
- 1D
- 3.36%
- 1M
- 7.43%
- YTD
- 2.96%
- 6M
- 1.41%
- 1Y
- 5.88%
- 3Y*
- 10.39%
- 5Y*
- 20.01%
- 10Y*
- 19.01%
Benchmark (S&P 500 Index)
- 1D
- -0.37%
- 1M
- -0.01%
- YTD
- 9.16%
- 6M
- 8.64%
- 1Y
- 25.22%
- 3Y*
- 19.78%
- 5Y*
- 11.99%
- 10Y*
- 13.88%
VRTX Monthly Returns History
Based on dividend-adjusted daily data since Jul 24, 1991, VRTX's average daily return is +0.12%, while the average monthly return is +2.17%. At this rate, an investment would double in approximately 2.7 years.
Historically, 55% of months were positive and 45% were negative. The best month was Feb 2000 with a return of +77.2%, while the worst month was Sep 2001 at -51.1%. The longest winning streak lasted 8 consecutive months, and the longest losing streak was 7 months.
On a daily basis, VRTX closed higher 48% of trading days. The best single day was Apr 19, 2013 with a return of +61.9%, while the worst single day was Nov 11, 2003 at -36.8%.
| Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec | Total | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2026 | 3.65% | 5.73% | -10.12% | -4.29% | 4.72% | 4.30% | 2.96% | ||||||
| 2025 | 14.65% | 3.92% | 1.05% | 5.09% | -13.24% | 0.71% | 2.62% | -14.41% | 0.16% | 8.66% | 1.89% | 4.55% | 12.58% |
| 2024 | 6.51% | -2.92% | -0.65% | -6.03% | 15.92% | 2.94% | 5.76% | 0.03% | -6.21% | 2.34% | -1.65% | -13.98% | -1.03% |
| 2023 | 11.88% | -10.15% | 8.54% | 8.14% | -5.04% | 8.76% | 0.12% | -1.14% | -0.17% | 4.13% | -2.02% | 14.68% | 40.90% |
| 2022 | 10.68% | -5.36% | 13.46% | 4.69% | -1.67% | 4.89% | -0.49% | 0.48% | 2.76% | 7.76% | 1.41% | -8.73% | 31.50% |
| 2021 | -3.07% | -7.22% | 1.10% | 1.54% | -4.39% | -3.36% | -0.02% | -0.64% | -9.44% | 1.95% | 1.09% | 17.47% | -7.08% |
Benchmark Metrics
Vertex Pharmaceuticals Incorporated has an annualized alpha of 21.35%, beta of 1.08, and R2 of 0.11 versus S&P 500 Index. Calculated based on daily prices since July 24, 1991.
- This stock captured 128.56% of S&P 500 Index gains and 104.14% of its losses - amplifying both gains and losses, but participating more in upside than downside.
- R2 of 0.11 means this stock moves largely independently of S&P 500 Index - capture ratios reflect limited market correlation rather than active downside protection. Consider using a more representative benchmark.
- Alpha
- 21.35%
- Beta
- 1.08
- R²
- 0.11
- Upside Capture
- 128.56%
- Downside Capture
- 104.14%
Return for Risk
Risk / Return Rank
VRTX ranks 46 for risk / return — on par with similar stocks. You're getting a typical balance of risk and reward. Not a standout, but not a red flag either — a reasonable choice if other factors align with your goals.
Return / Risk — by metrics
The table below present risk-adjusted performance metrics for Vertex Pharmaceuticals Incorporated (VRTX) and compare them to S&P 500 Index.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| VRTX | Benchmark | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | -1.86 | ||
| Sortino ratioReturn per unit of downside risk | -2.30 | ||
| Omega ratioGain probability vs. loss probability | 1.07 | 1.37 | -0.30 |
| Calmar ratioReturn relative to maximum drawdown | 0.25 | 2.78 | -2.53 |
| Martin ratioReturn relative to average drawdown | 0.52 | 12.44 | -11.92 |
Dividends
Dividend History
Drawdowns
Drawdowns Chart
The Drawdowns chart displays portfolio losses from any high point along the way. Drawdowns are calculated considering price movements and all distributions paid, if any.
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Worst Drawdowns
The table below displays the maximum drawdowns of the Vertex Pharmaceuticals Incorporated. A maximum drawdown is a measure of risk, indicating the largest reduction in portfolio value due to a series of losing trades.
The maximum drawdown for the Vertex Pharmaceuticals Incorporated was 91.77%, occurring on Nov 11, 2003. Recovery took 2677 trading sessions.
The current Vertex Pharmaceuticals Incorporated drawdown is 9.67%.
Related event | Drawdown | Fall | Recovery | Underwater |
|---|---|---|---|---|
2003 bear market2003 | -91.77%Nov 2003 | 3y 8d | 10y 7mo | 13y 8moNov 2000 - Jul 2014 |
1998 bear market1998 | -70.17%Aug 1998 | 1y 6mo | 1y 5mo | 2y 11moFeb 1997 - Feb 2000 |
1993 bear market1993 | -60.87%Feb 1993 | 1y 1mo | 7mo 21d | 1y 9moJan 1992 - Oct 1993 |
Dot-com crash2000–2002 | -55.25%Apr 2000 | 1mo 8d | 2mo 3d | 3mo 11dMar 2000 - Jun 2000 |
2016 bear market2016 | -49.10%Dec 2016 | 1y 4mo | 6mo 29d | 1y 11moAug 2015 - Jul 2017 |
Drawdown Indicators
| VRTX | Benchmark | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -91.77% | -56.78% | -34.99% |
Max Drawdown (1Y)Largest decline over 1 year | -23.56% | -9.10% | -14.46% |
Max Drawdown (3Y)Largest decline over 3 years | -29.07% | -18.90% | -10.17% |
Max Drawdown (5Y)Largest decline over 5 years | -29.07% | -25.43% | -3.64% |
Max Drawdown (10Y)Largest decline over 10 years | -41.60% | -33.92% | -7.68% |
Current DrawdownCurrent decline from peak | -9.67% | -1.80% | -7.87% |
Average DrawdownAverage peak-to-trough decline | -37.72% | -10.71% | -27.01% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 11.35% | 2.03% | +9.32% |
Volatility
Volatility Chart
The chart below shows the rolling one-month volatility.
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Financials
Financial Performance
The chart below illustrates the trends in the financial health of Vertex Pharmaceuticals Incorporated over time, highlighting three key metrics: Total Revenue, Earnings Before Interest and Taxes (EBIT), and Net Income.
Valuation
The Valuation section provides an overview of how Vertex Pharmaceuticals Incorporated is priced in the market compared to other companies in the Biotechnology industry. It includes key financial ratios that help investors assess whether the stock is undervalued or overvalued.
PE Ratio
The chart displays the Price-to-Earnings (P/E) ratio for VRTX, comparing it with other companies in the Biotechnology industry. Currently, VRTX has a P/E ratio of 27.7. This P/E ratio is in line with the industry average, suggesting the stock may be fairly valued relative to its earnings.
PEG Ratio
The chart shows the Price/Earnings to Growth (PEG) ratio for VRTX compared to other companies in the Biotechnology industry. VRTX currently has a PEG ratio of 2.3. This PEG ratio is higher than the industry average, which may suggest the stock is overvalued relative to its expected earnings growth.
PS Ratio
This chart shows the Price-to-Sales (P/S) ratio for VRTX relative to other companies in the Biotechnology industry. Currently, VRTX has a P/S ratio of 9.8. This P/S ratio falls within the average range for the industry, suggesting the stock is fairly valued based on its revenue.
PB Ratio
The chart illustrates the Price-to-Book (P/B) ratio for VRTX in comparison with other companies in the Biotechnology industry. Currently, VRTX has a P/B value of 4.5. This P/B ratio is in line with the industry average, suggesting the stock is valued fairly in relation to its book value.
Income Statement
| TTM | |
|---|---|
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Total Revenue | — |
Cost Of Revenue | — |
Gross Profit | — |
Operating Expenses | — |
Selling, General & Admin Expenses | — |
R&D Expenses | — |
Depreciation And Amortization | — |
Total Operating Expenses | — |
Income | — |
Income Before Tax | — |
Operating Income | — |
EBITDA | — |
EBIT | — |
Earnings From Continuing Operations | — |
Net Income | — |
Income Tax Expense | — |
Other Non-Operating Income (Expenses) | — |
Extraordinary Items | — |
Discontinued Operations | — |
Effect Of Accounting Charges | — |
Non Recurring | — |
Minority Interest | — |
Other Items | — |
Interest Income | — |
Interest Expense | — |
Net Interest Income | — |
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