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ISIN
US92532F1003
CUSIP
92532F100
IPO Date
Jul 24, 1991

Highlights

Market Cap
$119.64B
Enterprise Value
$114.38B
EPS (TTM)
$16.87
PE Ratio
27.68
PEG Ratio
2.30
Total Revenue (TTM)
$12.26B
Gross Profit (TTM)
$10.57B
EBITDA (TTM)
$5.19B
Year Range
$362.50 - $507.92
Target Price
$552.27
ROA (TTM)
16.38%
ROE (TTM)
16.38%

Share Price Chart


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Performance

VRTX Performance Chart

Vertex Pharmaceuticals Incorporated (VRTX) is up 3.0% since the beginning of the year. At $467 per share, VRTX is trading 8.1% below its 52-week high of $508. Investors who bought $1,000 worth of VRTX shares 5 years ago would now be looking at an investment worth $2,489.


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S&P 500 Index

Returns By Period

Vertex Pharmaceuticals Incorporated (VRTX) has returned 2.96% so far this year and 5.88% over the past 12 months. Looking at the last ten years, VRTX has achieved an annualized return of 19.01%, outperforming the S&P 500 Index benchmark, which averaged 13.88% per year.


Vertex Pharmaceuticals Incorporated

1D
3.36%
1M
7.43%
YTD
2.96%
6M
1.41%
1Y
5.88%
3Y*
10.39%
5Y*
20.01%
10Y*
19.01%

Benchmark (S&P 500 Index)

1D
-0.37%
1M
-0.01%
YTD
9.16%
6M
8.64%
1Y
25.22%
3Y*
19.78%
5Y*
11.99%
10Y*
13.88%
*Multi-year figures are annualized to reflect compound growth (CAGR)

VRTX Monthly Returns History

Based on dividend-adjusted daily data since Jul 24, 1991, VRTX's average daily return is +0.12%, while the average monthly return is +2.17%. At this rate, an investment would double in approximately 2.7 years.

Historically, 55% of months were positive and 45% were negative. The best month was Feb 2000 with a return of +77.2%, while the worst month was Sep 2001 at -51.1%. The longest winning streak lasted 8 consecutive months, and the longest losing streak was 7 months.

On a daily basis, VRTX closed higher 48% of trading days. The best single day was Apr 19, 2013 with a return of +61.9%, while the worst single day was Nov 11, 2003 at -36.8%.


JanFebMarAprMayJunJulAugSepOctNovDecTotal
20263.65%5.73%-10.12%-4.29%4.72%4.30%2.96%
202514.65%3.92%1.05%5.09%-13.24%0.71%2.62%-14.41%0.16%8.66%1.89%4.55%12.58%
20246.51%-2.92%-0.65%-6.03%15.92%2.94%5.76%0.03%-6.21%2.34%-1.65%-13.98%-1.03%
202311.88%-10.15%8.54%8.14%-5.04%8.76%0.12%-1.14%-0.17%4.13%-2.02%14.68%40.90%
202210.68%-5.36%13.46%4.69%-1.67%4.89%-0.49%0.48%2.76%7.76%1.41%-8.73%31.50%
2021-3.07%-7.22%1.10%1.54%-4.39%-3.36%-0.02%-0.64%-9.44%1.95%1.09%17.47%-7.08%

Benchmark Metrics

Vertex Pharmaceuticals Incorporated has an annualized alpha of 21.35%, beta of 1.08, and R2 of 0.11 versus S&P 500 Index. Calculated based on daily prices since July 24, 1991.

  • This stock captured 128.56% of S&P 500 Index gains and 104.14% of its losses - amplifying both gains and losses, but participating more in upside than downside.
  • R2 of 0.11 means this stock moves largely independently of S&P 500 Index - capture ratios reflect limited market correlation rather than active downside protection. Consider using a more representative benchmark.

Alpha
21.35%
Beta
1.08
0.11
Upside Capture
128.56%
Downside Capture
104.14%

Return for Risk

Risk / Return Rank

VRTX ranks 46 for risk / return — on par with similar stocks. You're getting a typical balance of risk and reward. Not a standout, but not a red flag either — a reasonable choice if other factors align with your goals.


VRTX Risk / Return Rank: 4646
Overall Rank
VRTX Sharpe Ratio Rank: 4848
Sharpe Ratio Rank
VRTX Sortino Ratio Rank: 4242
Sortino Ratio Rank
VRTX Omega Ratio Rank: 4444
Omega Ratio Rank
VRTX Calmar Ratio Rank: 4848
Calmar Ratio Rank
VRTX Martin Ratio Rank: 4848
Martin Ratio Rank
The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

Return / Risk — by metrics

The table below present risk-adjusted performance metrics for Vertex Pharmaceuticals Incorporated (VRTX) and compare them to S&P 500 Index.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.


VRTXBenchmarkDifference
Sharpe ratioReturn per unit of total volatility

-1.86

Sortino ratioReturn per unit of downside risk

-2.30

Omega ratioGain probability vs. loss probability

1.07

1.37

-0.30

Calmar ratioReturn relative to maximum drawdown

0.25

2.78

-2.53

Martin ratioReturn relative to average drawdown

0.52

12.44

-11.92

Dividends

Dividend History


Vertex Pharmaceuticals Incorporated doesn't pay dividends

Drawdowns

Drawdowns Chart

The Drawdowns chart displays portfolio losses from any high point along the way. Drawdowns are calculated considering price movements and all distributions paid, if any.


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Worst Drawdowns

The table below displays the maximum drawdowns of the Vertex Pharmaceuticals Incorporated. A maximum drawdown is a measure of risk, indicating the largest reduction in portfolio value due to a series of losing trades.

The maximum drawdown for the Vertex Pharmaceuticals Incorporated was 91.77%, occurring on Nov 11, 2003. Recovery took 2677 trading sessions.

The current Vertex Pharmaceuticals Incorporated drawdown is 9.67%.


Related event

Drawdown

Fall

Recovery

Underwater

2003 bear market2003
-91.77%Nov 2003
3y 8d10y 7mo
13y 8moNov 2000 - Jul 2014
1998 bear market1998
-70.17%Aug 1998
1y 6mo1y 5mo
2y 11moFeb 1997 - Feb 2000
1993 bear market1993
-60.87%Feb 1993
1y 1mo7mo 21d
1y 9moJan 1992 - Oct 1993
Dot-com crash2000–2002
-55.25%Apr 2000
1mo 8d2mo 3d
3mo 11dMar 2000 - Jun 2000
2016 bear market2016
-49.10%Dec 2016
1y 4mo6mo 29d
1y 11moAug 2015 - Jul 2017

Drawdown Indicators


VRTXBenchmarkDifference

Max Drawdown

Largest peak-to-trough decline

-91.77%

-56.78%

-34.99%

Max Drawdown (1Y)

Largest decline over 1 year

-23.56%

-9.10%

-14.46%

Max Drawdown (3Y)

Largest decline over 3 years

-29.07%

-18.90%

-10.17%

Max Drawdown (5Y)

Largest decline over 5 years

-29.07%

-25.43%

-3.64%

Max Drawdown (10Y)

Largest decline over 10 years

-41.60%

-33.92%

-7.68%

Current Drawdown

Current decline from peak

-9.67%

-1.80%

-7.87%

Average Drawdown

Average peak-to-trough decline

-37.72%

-10.71%

-27.01%

Ulcer Index

Depth and duration of drawdowns from previous peaks

11.35%

2.03%

+9.32%

Volatility

Volatility Chart

The chart below shows the rolling one-month volatility.


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Financials

Financial Performance

The chart below illustrates the trends in the financial health of Vertex Pharmaceuticals Incorporated over time, highlighting three key metrics: Total Revenue, Earnings Before Interest and Taxes (EBIT), and Net Income.


Annual
Quarterly

0.0

Valuation

The Valuation section provides an overview of how Vertex Pharmaceuticals Incorporated is priced in the market compared to other companies in the Biotechnology industry. It includes key financial ratios that help investors assess whether the stock is undervalued or overvalued.


PE Ratio

The chart displays the Price-to-Earnings (P/E) ratio for VRTX, comparing it with other companies in the Biotechnology industry. Currently, VRTX has a P/E ratio of 27.7. This P/E ratio is in line with the industry average, suggesting the stock may be fairly valued relative to its earnings.

PEG Ratio

The chart shows the Price/Earnings to Growth (PEG) ratio for VRTX compared to other companies in the Biotechnology industry. VRTX currently has a PEG ratio of 2.3. This PEG ratio is higher than the industry average, which may suggest the stock is overvalued relative to its expected earnings growth.

PS Ratio

This chart shows the Price-to-Sales (P/S) ratio for VRTX relative to other companies in the Biotechnology industry. Currently, VRTX has a P/S ratio of 9.8. This P/S ratio falls within the average range for the industry, suggesting the stock is fairly valued based on its revenue.

PB Ratio

The chart illustrates the Price-to-Book (P/B) ratio for VRTX in comparison with other companies in the Biotechnology industry. Currently, VRTX has a P/B value of 4.5. This P/B ratio is in line with the industry average, suggesting the stock is valued fairly in relation to its book value.

Income Statement



TTM
Revenue

Total Revenue

Cost Of Revenue

Gross Profit

Operating Expenses

Selling, General & Admin Expenses

R&D Expenses

Depreciation And Amortization

Total Operating Expenses

Income

Income Before Tax

Operating Income

EBITDA

EBIT

Earnings From Continuing Operations

Net Income

Income Tax Expense

Other Non-Operating Income (Expenses)

Extraordinary Items

Discontinued Operations

Effect Of Accounting Charges

Non Recurring

Minority Interest

Other Items

Interest Income

Interest Expense

Net Interest Income

Values in undefined except per share items
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